Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Magdalena Jura"'
Autor:
Karolina Wołodko, Tjaša Šentjurc, Edyta Walewska, Elżbieta Laniecka, Magdalena Jura, António Galvão
Publikováno v:
Molecular Metabolism, Vol 91, Iss , Pp 102062- (2025)
Objectives: Susceptibility to obesity in humans is driven by the intricate interplay of genetic, environmental and behavioural factors. Moreover, the mechanisms linking maternal obesity to infertility remain largely understudied. In this study, we in
Externí odkaz:
https://doaj.org/article/77fc225ea4c34561889fc9680511ab8d
Autor:
Peter Kirwan, Richard G. Kay, Bas Brouwers, Vicente Herranz-Pérez, Magdalena Jura, Pierre Larraufie, Julie Jerber, Jason Pembroke, Theresa Bartels, Anne White, Fiona M. Gribble, Frank Reimann, I. Sadaf Farooqi, Stephen O'Rahilly, Florian T. Merkle
Publikováno v:
Molecular Metabolism, Vol 17, Iss , Pp 82-97 (2018)
Objective: The lack of pro-opiomelanocortin (POMC)-derived melanocortin peptides results in hypoadrenalism and severe obesity in both humans and rodents that is treatable with synthetic melanocortins. However, there are significant differences in POM
Externí odkaz:
https://doaj.org/article/a61f42e653954d9a945781cd864e4404
Autor:
Mingyan Zhu, Elana Henning, Beata K. Blaszczyk, Julia M. Keogh, Gary A. Wayman, Takuhiro Sonoyama, Peter Kirwan, Suzanne M. Appleyard, Magdalena Jura, Inês Barroso, I. Sadaf Farooqi, Bas Brouwers, Florian T. Merkle, Marko Hyvönen, David C. DeWitt, Lukas K. J. Stadler, Fuki M. Hisama
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation and plasticity. In rodents, genetic disruption of Bdnf and TrkB leads to weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddd268bbaac5938f458eea7a20b0c87
https://www.repository.cam.ac.uk/handle/1810/323400
https://www.repository.cam.ac.uk/handle/1810/323400
Publikováno v:
Biochimie. 124:124-133
Obesity depends on a close interplay between genetic and environmental factors. However, it is unknown how these factors interact to cause changes in the obese condition during the progression of obesity from the neonatal to the aged individual. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875d3689853f6a15c7400c6e7395eec6
https://doi.org/10.1016/j.biochi.2015.05.006
https://doi.org/10.1016/j.biochi.2015.05.006
Publikováno v:
Current Protocols in Neuroscience
Neurons in the hypothalamus orchestrate homeostatic physiological processes and behaviors essential for life. Defects in the function of hypothalamic neurons cause a spectrum of human diseases, including obesity, infertility, growth defects, sleep di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230264382f3f642fd9052025d0dddb72
https://www.repository.cam.ac.uk/handle/1810/267390
https://www.repository.cam.ac.uk/handle/1810/267390
Publikováno v:
Physiological Reports
Susceptibility to obesity changes during the course of life. We utilized the C57BL/6J (B6) and 129S mouse as a genetic model for variation in diet‐induced obesity to define the adiposity phenotypes from birth to maturity at 8 weeks‐of‐age. From
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce662dc690f98f9ae44163edfd4bca3
http://hdl.handle.net/10852/65213
http://hdl.handle.net/10852/65213
Autor:
Magdalena Jura, Leslie P. Kozak
Publikováno v:
AGE. 38
Obesity has become a major public health problem. Given the current increase in life expectancy, the prevalence of obesity also raises steadily among older age groups. The increase in life expectancy is often accompanied with additional years of susc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04dffc915859a04dfc2c8c70bbe046ab
https://doi.org/10.1007/s11357-016-9884-3
https://doi.org/10.1007/s11357-016-9884-3
Publikováno v:
Reproduction Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4283aa78d4ff040a6c8e0cb675652bed
https://doi.org/10.1530/repabs.1.p164
https://doi.org/10.1530/repabs.1.p164