Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Magdalena J Slusarz"'
Autor:
Bogdan A Danalache, Jolanta Gutkowska, Magdalena J Slusarz, Irena Berezowska, Marek Jankowski
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13643 (2010)
Oxytocin (OT), synthesized in the heart, has the ability to heal injured hearts and to promote cardiomyogenesis from stem cells. Recently, we reported that the OT-GKR molecule, a processing intermediate of OT, potently increased the spontaneous forma
Externí odkaz:
https://doaj.org/article/22975b2f8b2640d9904d1bd1ea57ed63
Publikováno v:
Journal of Peptide Science. 19:118-126
Vasopressin and oxytocin receptors belong to the superfamily of G protein-coupled receptors and play an important role in many physiological functions. They are also involved in a number of pathological conditions being important drug targets. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e729a25de21d2eab2501a8b941aca35f
https://doi.org/10.1002/psc.2485
https://doi.org/10.1002/psc.2485
Publikováno v:
Journal of Medicinal Chemistry. 49:2463-2469
In this study, four cyclic vasopressin (CYFQNCPRG-NH(2), AVP) analogues substituted at positions 2 and 3 with four combinations of enantiomers of N-methylphenylalanine have been investigated. Three-dimensional structures of analogues have been former
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa048b41aeaf9fd3c89f49d646285a2
https://doi.org/10.1021/jm051075m
https://doi.org/10.1021/jm051075m
Autor:
Magdalena J, Slusarz, Rafał, Slusarz, Rajmund, Kaźmierkiewicz, Jerzy, Trojnar, Kazimierz, Wisniewski, Jerzy, Ciarkowski
Publikováno v:
Protein & Peptide Letters. 10:295-302
The neurohypophyseal nonapeptide hormone oxytocin (OT) is the strongest uterotonic substance known and is responsible for the initiation of labor. Conversely, oxytocin antagonists blocking uterine OT receptor can suppress uterus contraction. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7f628139ceb2864a357f54f24a9bef
https://doi.org/10.2174/0929866033478898
https://doi.org/10.2174/0929866033478898
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 19(2)
Vasopressin and oxytocin receptors belong to the superfamily of G protein-coupled receptors and play an important role in many physiological functions. They are also involved in a number of pathological conditions being important drug targets. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe652455b750ec20cfd020c77b873cf3
https://pubmed.ncbi.nlm.nih.gov/23303737
https://pubmed.ncbi.nlm.nih.gov/23303737
Publikováno v:
Protein and peptide letters. 16(4)
The role of the internal water molecules in vasopressin and oxytocin receptors has been investigated via molecular dynamics simulations in hydrated membrane model. Several water molecules have been identified within the binding pockets of receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103ef1f2cfacce1673c3e75e8b6a65a3
https://pubmed.ncbi.nlm.nih.gov/19356129
https://pubmed.ncbi.nlm.nih.gov/19356129
Publikováno v:
Biopolymers. 82(6)
The conformations of [Arg8]vasopressin (AVP) analogues substituted at positions 2 and 3 with N-methylphenylalanine (MePhe) enantiomers were earlier investigated by using nuclear magnetic resonance (NMR) spectroscopy in aqueous solution. A comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd5b105737f675ada8b1b8ada43a0ae
https://pubmed.ncbi.nlm.nih.gov/16557499
https://pubmed.ncbi.nlm.nih.gov/16557499
Publikováno v:
Biopolymers. 81(5)
The vasopressin V2 receptor (V2R) belongs to the Class A G protein-coupled receptors (GPCRs). V2R is expressed in the renal collecting duct (CD), where it mediates the antidiuretic action of the neurohypophyseal hormone arginine vasopressin (CYFQNCPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f588985a9404671efbc485ff184cf1
https://pubmed.ncbi.nlm.nih.gov/16333859
https://pubmed.ncbi.nlm.nih.gov/16333859