Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Magdalena Grandin"'
Autor:
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 598-610 (2016)
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA. We show th
Externí odkaz:
https://doaj.org/article/e0445cac1cc6472395667e9686543812
Autor:
Kristie Gehlhaus, Natasha J. Caplen, Jason J. Pitt, Jennifer L Dine, Magdalena Grandin, Sirisha Chakka, Stanley Lipkowitz, Sireesha V. Garimella, Marion M. Nau
Publikováno v:
Breast Cancer Research : BCR
Introduction Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to its receptors, TRAIL-receptor 1 (TRAIL-R1) and TRAIL-receptor 2 (TRAIL-R2), leading to apoptosis by activation of caspase-8 and the downstream executioner caspases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c85854459a48eefb0a5f879f1a7e9e8
https://doi.org/10.1186/bcr3645
https://doi.org/10.1186/bcr3645
Autor:
Natasha J. Caplen, Sara Haddock, Patrick J. Grohar, Kristen Gehlhaus, Carleen Klumpp-Thomas, Eugen Buehler, Matt Harlow, Guillermo O. Rangel Rivera, Lee J. Helman, Magdalena Grandin, Scott E. Martin, Konrad Huppi, Nichole Maloney, Suntae Kim
Publikováno v:
Cancer Research. 75:479-479
Ewing sarcoma (ES) is a highly aggressive cancer of the bone and soft tissue. In ∼85% of ES tumors the primary oncogenic event is a t(11:22)(q24:q12) translocation that generates a fusion of the 5′ end of EWSR1 and the 3′ end of FLI1 referred t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e06d1d734918b66ab9bb616d8bc62b8
https://doi.org/10.1158/1538-7445.am2015-479
https://doi.org/10.1158/1538-7445.am2015-479
Autor:
Eugen Buehler, Carleen Klumpp-Thomas, Sara Haddock, Konrad Huppi, Patrick J. Grohar, Nichole Maloney, Suntae Kim, Scott E. Martin, Natasha J. Caplen, Nirmalya Sen, Jack Zhu, Magdalena Grandin, Matt Harlow, Maura O'Neill, Guillermo O. Rangel Rivera, Kristen Gehlhaus, Lee J. Helman, Tamara L. Jones
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 598-610 (2016)
SummaryEwing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f770df3f83b05806c869ee2f11c8fb6e