Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Magdalena Gebert"'
Autor:
Magdalena Gebert, Sylwia Bartoszewska, Lukasz Opalinski, James F. Collawn, Rafał Bartoszewski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract The unfolded protein response is a survival signaling pathway that is induced during various types of ER stress. Here, we determine IRE1’s role in miRNA regulation during ER stress. During induction of ER stress in human bronchial epitheli
Externí odkaz:
https://doaj.org/article/61931b810a8b4da1bd32d89864aa77c0
Autor:
Joanna I. Nowak, Anna M. Olszewska, Justyna M. Wierzbicka, Magdalena Gebert, Rafał Bartoszewski, Michał A. Żmijewski
Publikováno v:
Cells, Vol 13, Iss 1, p 11 (2023)
The genomic activity of 1,25(OH)2D3 is mediated by vitamin D receptor (VDR), whilst non-genomic is associated with protein disulfide isomerase family A member 3 (PDIA3). Interestingly, our recent studies documented that PDIA3 is also involved, direct
Externí odkaz:
https://doaj.org/article/3bdcd93edca143edb2937dba09976696
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1648 (2023)
Efficient brain function requires as much as 20% of the total oxygen intake to support normal neuronal cell function. This level of oxygen usage, however, leads to the generation of free radicals, and thus can lead to oxidative stress and potentially
Externí odkaz:
https://doaj.org/article/e548d12c86a5479aa65b905d39550336
Autor:
Magdalena Gebert, Maciej Jaśkiewicz, Adrianna Moszyńska, James F. Collawn, Rafał Bartoszewski
Publikováno v:
Cancers, Vol 12, Iss 11, p 3119 (2020)
Tremendous progress in RNAi delivery methods and design has allowed for the effective development of siRNA-based therapeutics that are currently under clinical investigation for various cancer treatments. This approach has the potential to revolution
Externí odkaz:
https://doaj.org/article/8bd7c6565d594a9782b28123fa70a16b
Publikováno v:
Open Biology, Vol 7, Iss 4 (2017)
In the post-genomic era, the goal of personalized medicine is to determine the correlation between genotype and phenotype. Developing high-throughput genotyping technologies such as genome-wide association studies (GWAS) and the 1000 Genomes Project
Externí odkaz:
https://doaj.org/article/f718158e2a71469eb42069e293e6181a
Autor:
Magdalena Gebert, Michał Dąbrowski, Rafal Bartoszewski, David K. Crossman, Piotr Madanecki, Sylwia Bartoszewska, Aleksandra Sobolewska, Aleksandra Cabaj, Jarosław Króliczewski, James F. Collawn
Publikováno v:
Cellular and Molecular Life Sciences
Accumulation of misfolded proteins in ER activates the unfolded protein response (UPR), a multifunctional signaling pathway that is important for cell survival. The UPR is regulated by three ER transmembrane sensors, one of which is inositol-requirin
Autor:
Maciej Jaśkiewicz, Adrianna Moszyńska, Magdalena Gebert, James F. Collawn, Rafał Bartoszewski
Publikováno v:
Gene. 868:147376
Autor:
Adrianna Moszyńska, Maciej Jaśkiewicz, Marcin Serocki, Aleksandra Cabaj, David K. Crossman, Sylwia Bartoszewska, Magdalena Gebert, Michał Dąbrowski, James F. Collawn, Rafal Bartoszewski
Publikováno v:
The FASEB Journal. 36
Autor:
Leszek Kalinowski, Magdalena Gebert, Anna Janaszak-Jasiecka, Rafal Bartoszewski, Aleksandra Sobolewska, Jarosław Króliczewski, Wojciech Kamysz, Renata Ochocka, James F. Collawn, Michał Dąbrowski, Aleksandra Cabaj, David K. Crossman, Sylwia Bartoszewska
Publikováno v:
The FEBS Journal. 287:2923-2947
Endoplasmic reticulum (ER) stress conditions promote a cellular adaptive mechanism called the unfolded protein response (UPR) that utilizes three stress sensors, inositol-requiring protein 1, protein kinase RNA-like ER kinase, and activating transcri
Autor:
David K. Crossman, Piotr Madanecki, Adrianna Moszyńska, Magdalena Gebert, Rafal Bartoszewski, Renata Ochocka, Aleksandra Cabaj, Anna Janaszak-Jasiecka, James F. Collawn, Sylwia Bartoszewska, Jarosław Króliczewski
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Small noncoding microRNAs (miRNAs) post-transcriptionally regulate a large portion of the human transcriptome. miRNAs have been shown to play an important role in the unfolded protein response (UPR), a cellular adaptive mechanism that is important in