Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Magdalena Gebala"'
Publikováno v:
eLife, Vol 8 (2019)
In eukaryotes, a first step towards the nuclear DNA compaction process is the formation of a nucleosome, which is comprised of negatively charged DNA wrapped around a positively charged histone protein octamer. Often, it is assumed that the complexat
Externí odkaz:
https://doaj.org/article/086ab7e1068d4d36b8d2f53165901bf5
Publikováno v:
Journal of the American Chemical Society
To better understand the forces that mediate nucleic acid compaction in biology, we developed the disulfide cross-linking approach xHEED (X-linking of Helices to measure Electrostatic Effects at Distance) to measure the distance-dependent encounter f
Autor:
Simone Pezzotti, Magdalena Gebala, Daniel Herschlag, Gerhard Schwaab, Martina Havenith, Chun Yu Ma
Publikováno v:
Phys Chem Chem Phys
Physical Chemistry Chemical Physics
Physical Chemistry Chemical Physics
Electrostatic interactions are central to the structure and function of nucleic acids, including their folding, condensation, and interaction with proteins and other charged molecules. These interactions are profoundly affected by ions surrounding nu
Autor:
Daliborka Jambrec, Magdalena Gebala
Publikováno v:
ChemElectroChem. 9
Autor:
Karolin Luger, Keda Zhou, Magdalena Gebala, Dustin Woods, Kousik Sundararajan, Garrett Edwards, Daniel Krzizike, Jeff Wereszczynski, Aaron Straight
Publikováno v:
Nature structuralmolecular biology. 29(4)
The histone variant CENP-A is the epigenetic determinant for the centromere, where it is interspersed with canonical H3 to form a specialized chromatin structure that nucleates the kinetochore. How nucleosomes at the centromere arrange into higher or
Autor:
Kousik Sundararajan, Karolin Luger, Aaron F. Straight, Garrett B. Edwards, Magdalena Gebala, Keda Zhou, Krzizike D, Jeffery M. Wereszczynski, Dustin C. Woods
The histone variant CENP-A is the epigenetic determinant for the centromere, where it is interspersed with canonical H3 to form a specialized chromatin structure that nucleates the kinetochore. The arrangement of nucleosomes at the centromere into hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad607cf2e286c230efe390d1af53eb08
https://doi.org/10.1101/2021.06.14.448351
https://doi.org/10.1101/2021.06.14.448351
Autor:
Magdalena Gebala, Daniel Herschlag
Publikováno v:
Biophys J
Ribonucleic acids are one of the most charged polyelectrolytes in nature, and understanding of their electrostatics is fundamental to their structure and biological functions. An effective way to characterize the electrostatic field generated by nucl
Autor:
Namita Bisaria, Magdalena Gebala, Charles Limouse, Daniel Herschlag, Steve Bonilla, Hideo Mabuchi
Publikováno v:
Journal of the American Chemical Society
Decades of study of the RNA folding problem have revealed that diverse and complex structured RNAs are built from a common set of recurring structural motifs, leading to the perspective that a generalizable model of RNA folding may be developed from
Publikováno v:
Journal of the American Chemical Society. 139:7540-7548
The high charge density of nucleic acids and resulting ion atmosphere profoundly influence the conformational landscape of RNA and DNA and their association with small molecules and proteins. Electrostatic theories have been applied to quantitatively
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
In eukaryotes, a first step towards the nuclear DNA compaction process is the formation of a nucleosome, which is comprised of negatively charged DNA wrapped around a positively charged histone protein octamer. Often, it is assumed that the complexat