Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Magdalena Gassowska-Dobrowolska"'
Autor:
Anna Wilkaniec, Magdalena Gąssowska-Dobrowolska, Marcin Strawski, Agata Adamczyk, Grzegorz A. Czapski
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background Cyclin-dependent kinase 5 (Cdk5) belongs to the family of proline-directed serine/threonine kinases and plays a critical role in neuronal differentiation, migration, synaptogenesis, plasticity, neurotransmission and apoptosis. The
Externí odkaz:
https://doaj.org/article/ceab238d0c8240d09f3c8fd9287ca4d3
Autor:
Magdalena Cieślik, Magdalena Gąssowska-Dobrowolska, Henryk Jęśko, Grzegorz A. Czapski, Anna Wilkaniec, Aleksandra Zawadzka, Agnieszka Dominiak, Rafał Polowy, Robert K. Filipkowski, Paweł M. Boguszewski, Magdalena Gewartowska, Małgorzata Frontczak-Baniewicz, Grace Y. Sun, David Q. Beversdorf, Agata Adamczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4097 (2020)
Maternal immune activation (MIA), induced by infection during pregnancy, is an important risk factor for neuro-developmental disorders, such as autism. Abnormal maternal cytokine signaling may affect fetal brain development and contribute to neurobio
Externí odkaz:
https://doaj.org/article/d28eb6b7fa984da58d828160b28b1fc2
Autor:
Anna Wilkaniec, Magdalena Cieślik, Emilia Murawska, Lidia Babiec, Magdalena Gąssowska-Dobrowolska, Ewelina Pałasz, Henryk Jęśko, Agata Adamczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3959 (2020)
The purinergic P2X7 receptor (P2X7R) belongs to a family of trimeric ion channels that are gated by extracellular adenosine 5′-triphosphate (ATP). Several studies have pointed to a role of P2X7R-dependent signalling in Parkinson's disease (PD)-rela
Externí odkaz:
https://doaj.org/article/9d054eb2acdf481b9da62d624bfcc47a
Autor:
Magdalena Gąssowska-Dobrowolska, Magdalena Cieślik, Grzegorz Arkadiusz Czapski, Henryk Jęśko, Małgorzata Frontczak-Baniewicz, Magdalena Gewartowska, Agnieszka Dominiak, Rafał Polowy, Robert Kuba Filipkowski, Lidia Babiec, Agata Adamczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3576 (2020)
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental conditions categorized as synaptopathies. Environmental risk factors contribute to ASD aetiology. In particular, prenatal exposure to the anti-epileptic drug valproic aci
Externí odkaz:
https://doaj.org/article/92af6eafdf5a48d09e238d284507ee24
Autor:
Mateusz Bosiacki, Magdalena Gąssowska-Dobrowolska, Klaudyna Kojder, Marta Fabiańska, Dariusz Jeżewski, Izabela Gutowska, Anna Lubkowska
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4108 (2019)
Extracellular matrix (ECM) molecules that are released by neurons and glial cells form perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose structure is still not known in detail, surround cell bodies and dendrites, wh
Externí odkaz:
https://doaj.org/article/e3f0d94e8a0d4330a3cb6bc508419491
Autor:
Magdalena Cieślik, Magdalena Gassowska-Dobrowolska, Aleksandra Zawadzka, Małgorzata Frontczak-Baniewicz, Magdalena Gewartowska, Agnieszka Dominiak, Grzegorz A. Czapski, Agata Adamczyk
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders in offspring, but the pathomechanism is largely unknown. The aim of our study was to analyse the molecular mechanisms contributing to synaptic alterations in hippocamp
Externí odkaz:
https://doaj.org/article/0a515474976d413fa18d9a8f497e03f5
Autor:
Agnieszka Dominiak, Agata Adamczyk, Grzegorz A. Czapski, Małgorzata Frontczak-Baniewicz, Magdalena Cieślik, Magdalena Gassowska-Dobrowolska, Aleksandra Zawadzka, Magdalena Gewartowska
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders in offspring, but the pathomechanism is largely unknown. The aim of our study was to analyse the molecular mechanisms contributing to synaptic alterations in hippocamp
Autor:
Magdalena Gąssowska-Dobrowolska, Mikołaj Chlubek, Agnieszka Kolasa, Patrycja Tomasiak, Jan Korbecki, Katarzyna Skowrońska, Maciej Tarnowski, Marta Masztalewicz, Irena Baranowska-Bosiacka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9903 (2023)
Neuroinflammation is one of the postulated mechanisms for Pb neurotoxicity. However, the exact molecular mechanisms responsible for its pro-inflammatory effect are not fully elucidated. In this study, we examined the role of glial cells in neuroinfla
Externí odkaz:
https://doaj.org/article/194f24284597488bb12344114900b204
Autor:
Magdalena Gąssowska-Dobrowolska, Grzegorz A. Czapski, Magdalena Cieślik, Karolina Zajdel, Małgorzata Frontczak-Baniewicz, Lidia Babiec, Agata Adamczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7303 (2023)
Tuberous sclerosis complex (TSC) is a rare genetic multisystem disorder caused by loss-of-function mutations in the tumour suppressors TSC1/TSC2, both of which are negative regulators of the mammalian target of rapamycin (mTOR) kinase. Importantly, m
Externí odkaz:
https://doaj.org/article/94f6fe6186f24fa9a7100d975d473e93
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3031 (2022)
Autism spectrum disorders (ASD) are neurodevelopmental diseases characterised by deficits in social communication, restricted interests, and repetitive behaviours. The growing body of evidence points to a role for cerebellar changes in ASD pathology.
Externí odkaz:
https://doaj.org/article/215155481d24443f8a044f2a70feed02