New Steroidal Selenides as Proapoptotic Factors

Autor: Izabella Jastrzebska, Natalia Wawrusiewicz-Kurylonek, Paweł A. Grześ, Artur Ratkiewicz, Ewa Grabowska, Magdalena Czerniecka, Urszula Czyżewska, Adam Tylicki

Publikováno v: Molecules, Vol 28, Iss 22, p 7528 (2023)

Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI50 25.0 µM, almost complete growth inhibition after three days of culture, and over

Externí odkaz: https://doaj.org/article/369cfa1756a740dea54c096842445051

Differences in the efficiency of 3-deazathiamine and oxythiamine pyrophosphates as inhibitors of pyruvate dehydrogenase complex and growth of HeLa cells

Autor: Magdalena Czerniecka, Zenon Łotowski, Urszula Czyzewska, Adam Tylicki, Aneta Zambrzycka, Ewa Grabowska

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 122-129 (2021)

Oxythiamine (OT) and 3-deazathiamine (DAT) are the antimetabolites of thiamine. The aim of study was to compare the effects of OT and DAT pyrophosphates (-PP) on the kinetics of mammalian pyruvate dehydrogenase complex (PDHC) and the in vitro culture

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e169e83d1e8792de41d347ecb7b99b3e
https://pubmed.ncbi.nlm.nih.gov/33187452

Polyenes in therapy of mycosis - characteristics and mechanisms of resistance

Autor: Magdalena Czerniecka, Urszula Czyżewska, Marek Bartoszewicz, Adam Tylicki, Ewa Grabowska

Publikováno v: National Information Processing Institute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a9011ee39a67a45a76a769c1d11f45ee
https://katalogi.uwb.edu.pl/F?func=full-set-set&set_number=002368&set_entry=000006&format=999