Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Magdalena C. Zlatescu"'
Publikováno v:
Cancer Research. 67:580-584
Methylation of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter (i.e., gene silencing) occurs in 40% to 50% of patients with glioblastoma and predicts benefit from temozolomide chemotherapy; when unmethylated, MGMT repairs DNA damage i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a2f1aa6105757abca1123dd13e756d
https://doi.org/10.1158/0008-5472.can-06-2782
https://doi.org/10.1158/0008-5472.can-06-2782
Autor:
Masahiro Mizoguchi, Rebecca A. Betensky, J. Gregory Cairncross, Magdalena C. Zlatescu, Joseph F. Megyesi, Yoshifumi Okada, David N. Louis, Peter A. Forsyth, Hikaru Sasaki, Edward Kachur, Donald H. Lee
Publikováno v:
Clinical Cancer Research. 10:4303-4306
Molecular subsets of oligodendroglioma behave in biologically distinct ways. Their locations in the brain, rates of growth, and responses to therapy differ with their genotypes. Retrospectively, we inquired whether allelic loss of chromosomal arms 1p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ca54941c440dbaa02840e46624fedf
https://doi.org/10.1158/1078-0432.ccr-04-0209
https://doi.org/10.1158/1078-0432.ccr-04-0209
Autor:
Andrea N. Cutone, J. Gregory Cairncross, David N. Louis, Loki Johnk, Magdalena C. Zlatescu, Rebecca A. Betensky, Hikaru Sasaki
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 61:58-63
Allelic loss of chromosome 1p predicts increased chemosensitivity and better survival in oligodendroglial tumors. Clinical testing for 1p loss in oligodendroglial tumors at our hospital has allowed us to postulate that certain histological appearance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e886b5806ce4061b5e0d44de716784d
https://doi.org/10.1093/jnen/61.1.58
https://doi.org/10.1093/jnen/61.1.58
Autor:
Cairncross Jg, Taylor, Magdalena C. Zlatescu, Yasushi Ino, David N. Louis, Schwartz M, Ang Lc, Janet Perry, Becker Le, Anat Stemmer-Rachamimov
Publikováno v:
Journal of Neurosurgery. 90:946-950
✓ Patients with Turcot syndrome (TS) are predisposed to colon tumors and primary brain tumors, typically glioblastomas or medulloblastomas. The authors describe a patient with TS featuring a known germline mutation of exon 5 of the hPMS2 mismatch r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d35445c3527215f266c02399a11312
https://doi.org/10.3171/jns.1999.90.5.0946
https://doi.org/10.3171/jns.1999.90.5.0946
Autor:
Gloria Roldán, David Schiff, Douglas J. Demetrick, Gregory Cairncross, Peter A. Forsyth, Robert J. Sevick, Magdalena C. Zlatescu, J. Ross Mitchell, Elizabeth Yan, Jay Easaw, Angelique E. Sijben, Robert A. Brown, Ian F. Parney
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(8)
Background: Some patients with low-grade glioma have extraordinarily long survival times; current, early treatment does not prolong their lives. For this reason, therapies that sometimes have neurologic side effects are often deferred intentionally.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec77f70ab16fab3f4c2144c3298fe14
https://pubmed.ncbi.nlm.nih.gov/18413825
https://pubmed.ncbi.nlm.nih.gov/18413825
Autor:
Rebecca A. Betensky, David N. Louis, Magdalena C. Zlatescu, Yasushi Ino, Hikaru Sasaki, J. Gregory Cairncross
Allelic loss of 10q is a common genetic event in malignant gliomas, with three 10q tumor suppressor genes, ERCC6, PTEN, and DMBT1, putatively implicated in the most common type of malignant glioma, glioblastoma. Anaplastic oligodendroglioma, another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c96a078741087e436863ba472b089e
https://europepmc.org/articles/PMC1850425/
https://europepmc.org/articles/PMC1850425/
Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas
Autor:
Y Ino, Keisuke Ueki, J. G. Cairncross, Barbara Fisher, Glenn Bauman, Larry Stitt, David N. Louis, David R. Macdonald, Magdalena C. Zlatescu
Publikováno v:
International journal of radiation oncology, biology, physics. 48(3)
Allelic loss of the short arm of chromosome 1 predicts radiographic response to chemotherapy and long overall survival times in patients with anaplastic oligodendrogliomas. Using a database of patients with oligodendrogliomas in whom chromosome 1p st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00353871807cd6ebe57a29b8323cfc5
https://pubmed.ncbi.nlm.nih.gov/11020580
https://pubmed.ncbi.nlm.nih.gov/11020580
Autor:
J. Gregory Cairncross, David A. Ramsay, Hikaru Sasaki, Yasushi Ino, Anat Stemmer-Rachamimov, Sarah Jhung, David R. Macdonald, Magdalena C. Zlatescu, Andreas von Deimling, David N. Louis
Publikováno v:
Journal of neurosurgery. 92(6)
Object. Allelic loss of chromosome 1p is a powerful predictor of tumor chemosensitivity and prolonged survival in patients with anaplastic oligodendrogliomas. Chromosome 1p loss also occurs in astrocytic and oligoastrocytic gliomas, although less com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0dbb84c799af32ccf90eed3707fd26
https://pubmed.ncbi.nlm.nih.gov/10839286
https://pubmed.ncbi.nlm.nih.gov/10839286
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 58:512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1b5e69c7c0446a6046db4699180545d
https://doi.org/10.1097/00005072-199905000-00025
https://doi.org/10.1097/00005072-199905000-00025
Autor:
SASAKI, HIKARU, ZLATESCU, MAGDALENA C., BETENSKY, REBECCA A., JOHNK, LOKI B., CUTONE, ANDREA N., CAIRNCROSS, J. GREGORY, LOUIS, DAVID N.
Publikováno v:
Journal of Neuropathology & Experimental Neurology; Jan2002, Vol. 61 Issue 1, p58-63, 6p