Výsledky vyhledávání - "Magdalena Boncler"

Akademický článek

Efficacy of a Combined Antiplatelet Therapy Is Not Affected by a Simultaneous Binding of Cangrelor and PSB 0777 to Albumin

Autor: Joanna Wzorek, Radosław Bednarek, Cezary Watala, Magdalena Boncler

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Concurrent administration of two drugs may complicate the management of acute coronary syndromes: competitive drug displacement diminishes drug binding and alters drug pharmacodynamics. We investigated the interaction of two antiplatelet compounds (P

Externí odkaz: https://doaj.org/article/3e02acd6733d49729565cae791374c34

Zobrazit plný text záznamu

Akademický článek

Extract from spent hop (Humulus lupulus L.) reduces blood platelet aggregation and improves anticoagulant activity of human endothelial cells in vitro

Autor: Boguslawa Luzak, Jacek Golanski, Tomasz Przygodzki, Magdalena Boncler, Dorota Sosnowska, Jan Oszmianski, Cezary Watala, Marcin Rozalski

Publikováno v: Journal of Functional Foods, Vol 22, Iss , Pp 257-269 (2016)

Spent hop extract (SHE) is hypothesized to possess multifaceted anticoagulant effect and to reduce platelet reactivity in a direct manner and to improve the antiplatelet action of endothelium. The results demonstrated that SHE, rich in flavanols (50%

Externí odkaz: https://doaj.org/article/1f7714ec4d5548f88192a0c86a948485

Zobrazit plný text záznamu

Akademický článek

Fibrinogen Glycation and Presence of Glucose Impair Fibrin Polymerization—An In Vitro Study of Isolated Fibrinogen and Plasma from Patients with Diabetes Mellitus

Autor: Boguslawa Luzak, Magdalena Boncler, Marcin Kosmalski, Ewelina Mnich, Lidia Stanczyk, Tomasz Przygodzki, Cezary Watala

Publikováno v: Biomolecules, Vol 10, Iss 6, p 877 (2020)

Background: Fibrin formation and structure may be affected by a plethora of factors, including both genetic and posttranslational modifications, such as glycation, nitration or acetylation. Methods: The present study examines the effect of fibrinogen

Externí odkaz: https://doaj.org/article/a2c0838d256b46469f121aae22d456d9

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Adenosine Receptor Agonists Exhibit Anti-Platelet Effects and the Potential to Overcome Resistance to P2Y12 Receptor Antagonists

Autor: Nina Wolska, Magdalena Boncler, Dawid Polak, Joanna Wzorek, Tomasz Przygodzki, Magdalena Gapinska, Cezary Watala, Marcin Rozalski

Publikováno v: Molecules, Vol 25, Iss 1, p 130 (2019)

Large inter-individual variation in platelet response to endogenous agonists and pharmacological agents, including resistance to antiplatelet therapy, prompts a search for novel platelet inhibitors and development new antithrombotic strategies. The p

Externí odkaz: https://doaj.org/article/63924ca330fe4bfd90e4fbe2bcfd582c

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

A new approach for the assessment of the toxicity of polyphenol-rich compounds with the use of high content screening analysis.

Autor: Magdalena Boncler, Jacek Golanski, Magdalena Lukasiak, Malgorzata Redzynia, Jaroslaw Dastych, Cezary Watala

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0180022 (2017)

The toxicity of in vitro tested compounds is usually evaluated based on AC50 values calculated from dose-response curves. However, there is a large group of compounds for which a standard four-parametric sigmoid curve fitting may be inappropriate for

Externí odkaz: https://doaj.org/article/b509b1af9fe74aee8a99973ba2a4d8cd

Zobrazit plný text záznamu

Akademický článek

The Multiple Faces of C-Reactive Protein—Physiological and Pathophysiological Implications in Cardiovascular Disease

Autor: Magdalena Boncler, Yi Wu, Cezary Watala

Publikováno v: Molecules, Vol 24, Iss 11, p 2062 (2019)

C-reactive protein (CRP) is an intriguing protein which plays a variety of roles in either physiological or pathophysiological states. For years it has been regarded merely as a useful biomarker of infection, tissue injury and inflammation, and it wa

Externí odkaz: https://doaj.org/article/e1880e77b9cf44a8b66c79a652baffa1

Zobrazit plný text záznamu

Plný text ve formátu HTML

Interactions of fentanyl with blood platelets and plasma proteins: platelet sensitivity to prasugrel metabolite is not affected by fentanyl under in vitro conditions

Autor: Radosław Bednarek, Boguslawa Luzak, Jacek Golański, Magdalena Boncler

Publikováno v: Pharmacological Reports. 75:423-441

Background Clinical trials indicate that fentanyl, like morphine, may impair intestinal absorption and thus decrease the efficacy of oral P2Y12 inhibitors, such as clopidogrel, ticagrelor, and prasugrel. However, the ability of fentanyl to directly n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c75481337c2d106089b5c9cbb1935d63
https://doi.org/10.1007/s43440-023-00447-7

Zobrazit plný text záznamu

Collagen-induced platelet reactivity assessed by multiple electrode aggregometry in patients on dual antiplatelet therapy or aspirin monotherapy

Autor: Patrycja Szymańska, Magdalena Boncler, Anna Marcinkiewicz, Mirosław Wilczyński, Jacek Golański

Publikováno v: Diagnostyka Laboratoryjna. 57:131-136

Introduction: Multiple electrode aggregometry (MEA) is used to assess platelet function and reactivity. This method allows for monitoring of antiplatelet therapy in patients and is important in the preoperative and perioperative periods, especially i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05a538d236453128aca786cf51c03dc4
https://doi.org/10.5604/01.3001.0015.8841

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání