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pro vyhledávání: '"Magdalena Bojko"'
Autor:
Magdalena Bojko, Katarzyna Węgrzyn, Emilia Sikorska, Piotr Ciura, Claire Battin, Peter Steinberger, Katarzyna Magiera-Mularz, Grzegorz Dubin, Adam Kulesza, Adam K. Sieradzan, Marta Spodzieja, Sylwia Rodziewicz-Motowidło
Publikováno v:
Translational Oncology, Vol 42, Iss , Pp 101892- (2024)
The PD-1/PD-L1 complex belongs to the group of inhibitory immune checkpoints and plays a critical role in immune regulation. The PD-1/PD-L1 axis is also responsible for immune evasion of cancer cells, and this complex is one of the main targets of im
Externí odkaz:
https://doaj.org/article/f56500fd70e44f229e66c4fb54d021eb
Autor:
Magdalena Bojko, Katarzyna Węgrzyn, Emilia Sikorska, Mikołaj Kocikowski, Maciej Parys, Claire Battin, Peter Steinberger, Małgorzata M. Kogut, Michał Winnicki, Adam K. Sieradzan, Marta Spodzieja, Sylwia Rodziewicz-Motowidło
Publikováno v:
Bojko, M, Węgrzyn, K, Sikorska, E, Kocikowski, M, Parys, M, Battin, C, Steinberger, P, Kogut, M M, Winnicki, M, Sieradzan, A K, Spodzieja, M & Rodziewicz-Motowidło, S 2022, ' Design, synthesis and biological evaluation of PD-1 derived peptides as inhibitors of PD-1/PD-L1 complex formation for cancer therapy ', Bioorganic Chemistry, vol. 128, 106047, pp. 1-15 . https://doi.org/10.1016/j.bioorg.2022.106047
Over the past few years, many molecules such as monoclonal antibodies, affibodies, nanobodies, and small compounds have been designed and tested as inhibitors of PD-1/PD-L1 complex formation. Some of them have been successfully implemented into clini
Autor:
Magdalena Bojko, Sylwia Rodziewicz-Motowidło, Katarzyna Guzik, Jacek Ryl, Tadeusz Ossowski, Tad A. Holak, Katarzyna Magiera-Mularz, Paweł Niedziałkowski, Marta Spodzieja, Anna Wcisło, Grzegorz Dubin
Publikováno v:
Bioelectrochemistry. 139:107742
This work describes the modification of a gold electrode with the BMS-8 compound that interacts with the Programmed Death-Ligand 1 (PD-L1), an immune checkpoint protein. The results show that we can confirm the presence of the sPD-L1 in the concentra