Specific Features of RNA Polymerases I and III: Structure and Assembly

Autor: Tomasz W. Turowski, Magdalena Boguta

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

RNA polymerase I (RNAPI) and RNAPIII are multi-heterogenic protein complexes that specialize in the transcription of highly abundant non-coding RNAs, such as ribosomal RNA (rRNA) and transfer RNA (tRNA). In terms of subunit number and structure, RNAP

Externí odkaz: https://doaj.org/article/794f28dba7074310800b7c0ee6de2455

Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes

Autor: Ewa Leśniewska, Magdalena Boguta

Publikováno v: Open Biology, Vol 7, Iss 2 (2017)

RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA. The originally defined yeast Pol III transcriptome appears to be expanding owing to the application of new methods. Also,

Externí odkaz: https://doaj.org/article/7b49f518638a4f1194ce5bc056e3956b

Reprogramming mRNA Expression in Response to Defect in RNA Polymerase III Assembly in the Yeast Saccharomyces cerevisiae

Autor: Małgorzata Cieśla, Alicja Armatowska, Izabela Rudzińska, Tomasz W. Turowski, Magdalena Boguta, Ewa Leśniewska

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 7298, p 7298 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 14
Rudzińska, I, Cieśla, M, Turowski, T W, Armatowska, A, Leśniewska, E & Boguta, M 2021, ' Reprogramming mRNA expression in response to defect in RNA polymerase III assembly in the yeast saccharomyces cerevisiae ', International Journal of Molecular Sciences, vol. 22, no. 14, 7298 . https://doi.org/10.3390/ijms22147298

The coordinated transcription of the genome is the fundamental mechanism in molecular biology. Transcription in eukaryotes is carried out by three main RNA polymerases: Pol I, II, and III. One basic problem is how a decrease in tRNA levels, by downre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88993804c98f32144de244e8c02440fb
https://www.mdpi.com/1422-0067/22/14/7298

Rbs1 protein, involved in RNA polymerase III complex assembly in the yeast Saccharomyces cerevisiae, induces a Gcn4 response and forms aggregates when overproduced

Autor: Izabela Rudzińska, Magdalena Boguta, Alicja Armatowska, Tomasz W. Turowski, Marta Płonka

Publikováno v: Gene. 809:146034

We previously reported the function of Rbs1 protein in RNA polymerase III complex assembly via interactions with both, proteins and mRNAs. Rbs1 is a poly(A)-binding protein. The R3H domain in Rbs1 is required for mRNA interactions. The present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942646a7bfe6877e8bf5e1388310263a
https://doi.org/10.1016/j.gene.2021.146034

Function of TFIIIC, RNA polymerase III initiation factor, in activation and repression of tRNA gene transcription

Autor: Malgorzata Ciesla, Magdalena Boguta, Ewa Skowronek

Publikováno v: Nucleic Acids Research

Transcription of transfer RNA genes by RNA polymerase III (Pol III) is controlled by general factors, TFIIIB and TFIIIC, and a negative regulator, Maf1. Here we report the interplay between TFIIIC and Maf1 in controlling Pol III activity upon the phy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4167a74b7e45fb9f4d2a9a5a8efd1147
http://europepmc.org/articles/PMC6182151