Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Magdalena Blazejczyk"'
Autor:
Franz Huschner, Jagoda Głowacka-Walas, James D. Mills, Katarzyna Klonowska, Kathryn Lasseter, John M. Asara, Romina Moavero, Christoph Hertzberg, Bernhard Weschke, Kate Riney, Martha Feucht, Theresa Scholl, Pavel Krsek, Rima Nabbout, Anna C. Jansen, Bořivoj Petrák, Jackelien van Scheppingen, Josef Zamecnik, Anand Iyer, Jasper J. Anink, Angelika Mühlebner, Caroline Mijnsbergen, Lieven Lagae, Paolo Curatolo, Julita Borkowska, Krzysztof Sadowski, Dorota Domańska-Pakieła, Magdalena Blazejczyk, Floor E. Jansen, Stef Janson, Malgorzata Urbanska, Aleksandra Tempes, Bart Janssen, Kamil Sijko, Konrad Wojdan, Sergiusz Jozwiak, Katarzyna Kotulska, Karola Lehmann, Eleonora Aronica, Jacek Jaworski, David J. Kwiatkowski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We present a comprehensive multi-omic analysis of the EPISTOP prospective clinical trial of early intervention with vigabatrin for pre-symptomatic epilepsy treatment in Tuberous Sclerosis Complex (TSC), in which 93 infants with TSC were foll
Externí odkaz:
https://doaj.org/article/4ebd3a42e79a421f9ec149801b6df580
Autor:
Mirte Scheper, Alessia Romagnolo, Zein Mersini Besharat, Anand M. Iyer, Romina Moavero, Christoph Hertzberg, Bernhard Weschke, Kate Riney, Martha Feucht, Theresa Scholl, Borivoj Petrak, Alice Maulisova, Rima Nabbout, Anna C. Jansen, Floor E. Jansen, Lieven Lagae, Malgorzata Urbanska, Elisabetta Ferretti, Aleksandra Tempes, Magdalena Blazejczyk, Jacek Jaworski, David J. Kwiatkowski, Sergiusz Jozwiak, Katarzyna Kotulska, Krzysztof Sadowski, Julita Borkowska, Paolo Curatolo, James D. Mills, Eleonora Aronica, EPISTOP Consortium Members
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1838 (2022)
Tuberous sclerosis complex (TSC) is a rare multi-system genetic disorder characterized by a high incidence of epilepsy and neuropsychiatric manifestations known as tuberous-sclerosis-associated neuropsychiatric disorders (TANDs), including autism spe
Externí odkaz:
https://doaj.org/article/f771935c50eb4ff39dc3c5c38aa4acd0
Autor:
Agata Gozdz, Oleksii Nikolaienko, Malgorzata Urbanska, Iwona A. Cymerman, Ewa Sitkiewicz, Magdalena Blazejczyk, Michal Dadlez, Clive R. Bramham, Jacek Jaworski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which regulates the synaptic content
Externí odkaz:
https://doaj.org/article/32506f9bfb8441bba8f6fb0530058634
Publikováno v:
Molecules, Vol 7, Iss 12, Pp 896-901 (2002)
A fluorimetric assay of aldehyde dehydrogenase isozymes, based on naphthaldehyde oxidation, is compared with Western Blotting analysis on several clinical samples obtained from surgery. The comparison reveals qualitatively good correlation of ALDH1A1
Externí odkaz:
https://doaj.org/article/2474e4d901a248a6b0f35dae9e476d31
Autor:
Matylda Macias, Magdalena Blazejczyk, Paulina Kazmierska, Bartosz Caban, Agnieszka Skalecka, Bartosz Tarkowski, Anna Rodo, Jan Konopacki, Jacek Jaworski
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64455 (2013)
Mammalian target of rapamycin (mTOR) is a protein kinase that senses nutrient availability, trophic factors support, cellular energy level, cellular stress, and neurotransmitters and adjusts cellular metabolism accordingly. Adequate mTOR activity is
Externí odkaz:
https://doaj.org/article/f4082017b5e4443fb539dfecdb2c6876
Autor:
Aleksandra Janusz-Kamińska, Agnieszka Brzozowska, Aleksandra Tempes, Malgorzata Urbanska, Magdalena Blazejczyk, Jacek Miłek, Juan Zeng, Katarzyna Kisielewska, Jacek Jaworski
Synaptic plasticity is a process that shapes neuronal connections during neurodevelopment, learning, and memory. Autophagy is a mechanism that allows cells to degrade their unnecessary or dysfunctional components. Autophagosomes appear at dendritic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b7f6b2c5ec3dcc4bcda3e122423d94
https://doi.org/10.1101/2022.05.20.492668
https://doi.org/10.1101/2022.05.20.492668
Publikováno v:
Human Molecular Genetics. 28:2107-2119
Several mosaic mutations of the mammalian/mechanistic target of rapamycin (mTOR) have recently been found in patients with cortical malformations, such as hemimegalencephaly (HME) and focal cortical dysplasia (FCD). Although all of them should activa
Autor:
Alicja Koscielny, Matylda Macias, Ryszard Przewlocki, Jacek Jaworski, Marcin Piechota, Magdalena Blazejczyk, Michal Korostynski, Aleksandra Tempes, Malgorzata Urbanska, Agnieszka Skalecka, Marcelina Firkowska
Publikováno v:
Molecular Neurobiology
Epileptogenesis is a process triggered by initial environmental or genetic factors that result in epilepsy and may continue during disease progression. Important parts of this process include changes in transcriptome and the pathological rewiring of
Autor:
Andrzej Nagalski, Malgorzata Perycz, Magdalena Blazejczyk, Lukasz Swiech, Jacek Jaworski, Anna R. Malik, Agata Gozdz, Malgorzata Urbanska
Publikováno v:
Journal of Biological Chemistry. 288:8544-8559
The shape of the dendritic arbor is one of the criteria of neuron classification and reflects functional specialization of particular classes of neurons. The development of a proper dendritic branching pattern strongly relies on interactions between
Autor:
Michael R. Kreutz, Magdalena Blazejczyk, Urszula Wojda, Christina Spilker, Adam Sobczak, Eckart D. Gundelfinger, Jacek Kuznicki, Hans-Gert Bernstein
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1762:66-72
The interaction between the EF-hand Ca(2+)-binding protein calmyrin and presenilin 2 (PS2) has been suggested to play a role in Alzheimer's disease (AD). We now report that calmyrin binds specifically endogenous PS2 and not PS1. However, binding appe