Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Magdalena Blaszkiewicz"'
Autor:
Jake W. Willows, Gilian Gunsch, Emma Paradie, Magdalena Blaszkiewicz, Jeffrey R. Tonniges, Maria F. Pino, Steven R. Smith, Lauren M. Sparks, Kristy L. Townsend
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106189- (2023)
Summary: Peripheral neuropathy, which can include axonal degeneration and/or demyelination, impacts adipose tissues with obesity, diabetes, and aging. However, the presence of demyelinating neuropathy had not yet been explored in adipose. Both demyel
Externí odkaz:
https://doaj.org/article/0a17f561f6304c6aa76f43e79b802080
Autor:
Magdalena Blaszkiewicz, Gilian Gunsch, Jake W. Willows, Miranda L. Gardner, Jesse A. Sepeda, Andrew R. Sas, Kristy L. Townsend
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Peripheral nerves allow a bidirectional communication between brain and adipose tissues, and many studies have clearly demonstrated that a loss of the adipose nerve supply results in tissue dysfunction and metabolic dysregulation. Neuroimmune cells c
Externí odkaz:
https://doaj.org/article/f8242b9540784c96b5f5a7ab201e3f4f
Autor:
Magdalena Blaszkiewicz, Elizabeth Wood, Sigi Koizar, Jake Willows, Ryan Anderson, Yu-Hua Tseng, James Godwin, Kristy L. Townsend
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-19 (2020)
Abstract Background Innervation of adipose tissue is essential for the proper function of this critical metabolic organ. Numerous surgical and chemical denervation studies have demonstrated how maintenance of brain-adipose communication through both
Externí odkaz:
https://doaj.org/article/05a03f18f6e14436bfa8dd5b280af5f2
Autor:
Kristy L. Townsend, Eleanor Pritchard, Jeannine M. Coburn, Young Mi Kwon, Magdalena Blaszkiewicz, Matthew D. Lynes, David L. Kaplan, Yu-Hua Tseng
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Objective: Increasing the mass and/or activity of brown adipose tissue (BAT) is one promising avenue for treating obesity and related metabolic conditions, given that BAT has a high potential for energy expenditure and is capable of improving glucose
Externí odkaz:
https://doaj.org/article/53b270743bda4d0b91f143c84a529e10
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101109- (2022)
Summary: Here we provide a clearing-free protocol for processing intact, whole mount subcutaneous white adipose tissue (scWAT) for immunofluorescence as an alternative to current clearing-based approaches. We use a combination of Z-depth reduction an
Externí odkaz:
https://doaj.org/article/a5a0fe9c6a484fdaa90b7e5bc4fd5413
Autor:
Jake W. Willows, Magdalena Blaszkiewicz, Amy Lamore, Samuel Borer, Amanda L. Dubois, Emma Garner, William P. Breeding, Karissa B. Tilbury, Andre Khalil, Kristy L. Townsend
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103127- (2021)
Summary: Little is known about the diversity and function of adipose tissue nerves, due in part to the inability to effectively visualize the tissue’s diverse nerve subtypes and the patterns of innervation across an intact depot. The tools to image
Externí odkaz:
https://doaj.org/article/6fe736739327491aae06088e39728da0
Autor:
Magdalena Blaszkiewicz, Jake W Willows, Amanda L Dubois, Stephen Waible, Kristen DiBello, Lila L Lyons, Cory P Johnson, Emma Paradie, Nicholas Banks, Katherine Motyl, Merilla Michael, Benjamin Harrison, Kristy L Townsend
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221766 (2019)
The difficulty in obtaining as well as maintaining weight loss, together with the impairment of metabolic control in conditions like diabetes and cardiovascular disease, may represent pathological situations of inadequate neural communication between
Externí odkaz:
https://doaj.org/article/01ddd7bee3d946ed8cd8819db7a718d5
Publikováno v:
Biology, Vol 8, Iss 1, p 10 (2019)
Brown and white adipose tissues are essential for maintenance of proper energy balance and metabolic health. In order to function efficiently, these tissues require both endocrine and neural communication with the brain. Brown adipose tissue (BAT), a
Externí odkaz:
https://doaj.org/article/6aeeec75b62d488983d99536e359d34e
Autor:
Jake W. Willows, Morganne Robinson, Zahra Alshahal, Samantha K. Morrison, Gargi Mishra, Harrison Cyr, Magdalena Blaszkiewicz, Gilian Gunsch, Sabrina DiPietro, Emma Paradie, Benjamin Tero, Anne Harrington, Larisa Ryzhova, Lucy Liaw, Peter C. Reifsnyder, David E. Harrison, Kristy L. Townsend
Publikováno v:
Aging Cell
Cover legend: The cover image is based on the Research Article Age‐related changes to adipose tissue and peripheral neuropathy in genetically diverse HET3 mice differ by sex and are not mitigated by rapamycin longevity treatment by Jake W. Willows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85aa5dafb8023f319c0d3e98c135ca3
https://europepmc.org/articles/PMC10086519/
https://europepmc.org/articles/PMC10086519/
Autor:
Magdalena Blaszkiewicz, Lydia Caron, Brooke Villinski, Joshua Passarelli, Jonathan Donnelly, Julia M. Towne, Naeemah M. Story, Erin Merchant, Furrukh S. Khan, Nuri Emanetoglu, Leonard Kass, Rosemary L. Smith, Kristy L. Townsend
Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes. Proactive treatment options remain limited, largely due to a lack of sensitive and convenient diagnostics, especially early in disease progression or specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6fdca2d634b2521527af5d3aba2147
https://doi.org/10.1101/2023.03.03.530993
https://doi.org/10.1101/2023.03.03.530993