Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Magdalena A, Budzinska"'
Autor:
Magda Markowska, Magdalena A. Budzinska, Anna Coenen-Stass, Senbai Kang, Ewa Kizling, Krzysztof Kolmus, Krzysztof Koras, Eike Staub, Ewa Szczurek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Discovering synthetic lethal (SL) gene partners of cancer genes is an important step in developing cancer therapies. However, identification of SL interactions is challenging, due to a large number of possible gene pairs, inherent noise and
Externí odkaz:
https://doaj.org/article/ca1dad2c26964888ab597e9bf0ca4423
Autor:
Alicja Rączkowska, Iwona Paśnik, Michał Kukiełka, Marcin Nicoś, Magdalena A. Budzinska, Tomasz Kucharczyk, Justyna Szumiło, Paweł Krawczyk, Nicola Crosetto, Ewa Szczurek
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background Despite the fact that tumor microenvironment (TME) and gene mutations are the main determinants of progression of the deadliest cancer in the world – lung cancer, their interrelations are not well understood. Digital pathology d
Externí odkaz:
https://doaj.org/article/b9d927256bad4ba687e5a6bb6f27c878
Autor:
Magda Markowska, Magdalena A Budzinska, Anna Coenen-Stass, Senbai Kang, Ewa Kizling, Krzysztof Kolmus, Krzysztof Koras, Eike Staub, Ewa Szczurek
Discovering synthetic lethal (SL) gene partners of cancer genes is an important step in developing cancer therapies. However, identification of SL interactions is challenging, due to a large number of possible gene pairs, inherent noise and confoundi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e346bbd106d705d346f8105bf446944
https://doi.org/10.1101/2022.07.07.499118
https://doi.org/10.1101/2022.07.07.499118
Novel Aspects of the Liver Microenvironment in Hepatocellular Carcinoma Pathogenesis and Development
Autor:
Thomas Tu, Magdalena A. Budzinska, Annette E. Maczurek, Robert Cheng, Anna Di Bartolomeo, Fiona J. Warner, Geoffrey W. McCaughan, Susan V. McLennan, Nicholas A. Shackel
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 6, Pp 9422-9458 (2014)
Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer that is derived from hepatocytes and is characterised by high mortality rate and poor prognosis. While HCC is driven by cumulative changes in the hepatocyte genome, it is increasingly
Externí odkaz:
https://doaj.org/article/98be9c65a75a43f2a0ac1ae7a2e2fde8
Autor:
Magdalena A Budzinska, Thomas Tu, William M H d'Avigdor, Geoffrey W McCaughan, Fabio Luciani, Nicholas A Shackel
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162586 (2016)
In hepatocellular carcinoma (HCC), somatic genome-wide DNA mutations are numerous, universal and heterogeneous. Some of these somatic mutations are drivers of the malignant process but the vast majority are passenger mutations. These passenger mutati
Externí odkaz:
https://doaj.org/article/40cffdb6863b47efb94ccf60efa57b74
Autor:
Łukasz Rączkowski, Iwona Paśnik, Michał Kukiełka, Marcin Nicoś, Magdalena A. Budzinska, Tomasz Kucharczyk, Justyna Szumiło, Paweł Krawczyk, Nicola Crosetto, Ewa Szczurek
Publikováno v:
BMC cancer. 22(1)
Background Despite the fact that tumor microenvironment (TME) and gene mutations are the main determinants of progression of the deadliest cancer in the world – lung cancer, their interrelations are not well understood. Digital pathology data provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b70aeca2659e16121a491db54b4a69
https://pubmed.ncbi.nlm.nih.gov/36131239
https://pubmed.ncbi.nlm.nih.gov/36131239
Autor:
Michał Kukiełka, Paweł Krawczyk, Tomasz Kucharczyk, Łukasz Rączkowski, Iwona Paśnik, Ewa Szczurek, Justyna Szumiło, Marcin Nicoś, Nicola Crosetto, Magdalena A. Budzinska
Despite the fact that tumor microenvironment (TME) and gene mutations are the main determinants of progression of the deadliest cancer in the world – lung cancer – their interrelations are not well understood. Digital pathology data provide a uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702da1df6aba4d068c89f640fce7a7d8
https://doi.org/10.1101/2021.10.09.462574
https://doi.org/10.1101/2021.10.09.462574
Autor:
Geoffrey C. Farrell, W. d’Avigdor, Susan V. McLennan, M Stapelberg, M. Lee, Geoffrey W. McCaughan, Thomas Tu, Magdalena A. Budzinska, James G. Kench, Nicholas A. Shackel, R Lam, Jacob George
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Despite advances in antiviral therapy, molecular drivers of Hepatitis C Virus (HCV)-related liver disease remain poorly characterised. Chronic infection with HCV genotypes (1 and 3) differ in presentation of liver steatosis and virological response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5141aa3e4088ee8f7c2e63c1830ec9d8
http://link.springer.com/article/10.1038/s41598-019-46664-0
http://link.springer.com/article/10.1038/s41598-019-46664-0
Publikováno v:
Viruses, Vol 9, Iss 4, p 75 (2017)
Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality. One peculiar observation in cells infected with HBV (or with closely‑related animal hepadnaviruses) is the presence of viral DNA integrati
Externí odkaz:
https://doaj.org/article/4df049de39124574adb305a8d984d34c
Publikováno v:
Emerging Microbes & Infections
Hepatitis B virus (HBV) integration into the host cell genome occurs early on in infection and reportedly induces pro-oncogenic changes in hepatocytes that drive HCC initiation. However, it remains unclear when these changes occur during hepatocarcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4314d923618ef10313a76bc766a5ee1a
https://doi.org/10.1038/s41426-018-0145-7
https://doi.org/10.1038/s41426-018-0145-7