Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Magdalena Łasoń-Tyburkiewicz"'
Autor:
Joanna M. Wierońska, Natalia Kłeczek, Piotr Gruca, Karolina Noworyta-Sokołowska, Mariusz Papp, Magdalena Łasoń-Tyburkiewicz, Anna Sławińska, Andrzej Pilc, Krystyna Gołembiowska, Dario Doller, Stevin H. Zorn
Publikováno v:
Psychopharmacology
Rationale Diverse preclinical studies suggest the potential therapeutic utility of the modulation of the glutamatergic system in brain via metabotropic glutamate (mGlu) receptors. Lu AF21934, a positive allosteric modulator of the mGlu4 receptor, was
Autor:
Katarzyna Stachowicz, Joanna M. Wierońska, Magdalena Łasoń-Tyburkiewicz, Mariusz Papp, Piotr Gruca, Andrzej Pilc, Anna Sławińska
Publikováno v:
Behavioural Brain Research. 256:298-304
mGlu(2/3) receptor agonists were shown to possess an antipsychotic-like potential in animal studies. Recent clinical investigations revealed that their antipsychotic potential might also manifest in humans. LY379268, the group II mGlu receptor orthos
Autor:
Piotr Gruca, Magdalena Łasoń-Tyburkiewicz, Joanna M. Wierońska, Dario Doller, Krzysztof Tokarski, Marcin Marciniak, Mariusz Papp, Magdalena Kusek, Katarzyna Stachowicz, Andrzej Pilc, Anna Sławińska
Publikováno v:
British Journal of Pharmacology. 169:1824-1839
Background and Purpose Because agonists at metabotropic glutamate receptors exert beneficial effects in schizophrenia, we have assessed the actions of Lu AF21934 and Lu AF32615, two chemically distinct, selective and brain-penetrant positive alloster
Autor:
Grazyna Ossowska, Gabriel Nowak, Małgorzata Wolak, Monika Zadrożna, Magdalena Łasoń-Tyburkiewicz, Mariusz Papp, Barbara Nowak, Magdalena Sowa-Kućma, Andrzej Pilc
Publikováno v:
Pharmacological Reports. 63:1539-1546
Reductions in the number and size of neurons in the medial prefrontal cortex (mPFC) have been documented in many post-mortem studies of depressed patients and animals exposed to stress. Here, we examined the effect of chronic unpredictable stress (CU
mGlu5-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia
Autor:
Mariusz Papp, Joanna M. Wierońska, Piotr Brański, Natalia Kłeczek, Monika Woźniak, Andrzej Pilc, Piotr Gruca, Magdalena Łasoń-Tyburkiewicz, Grzegorz Burnat
Diverse preclinical studies exploiting the modulation of the GABAergic and/or glutamatergic system in brain via metabotropic receptors suggest their potential therapeutic utility. GS39783 and CDPPB, positive allosteric modulators of GABAB and mGlu5 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5580348956754371bdf641682ca7f345
https://ruj.uj.edu.pl/xmlui/handle/item/106673
https://ruj.uj.edu.pl/xmlui/handle/item/106673
mGlu₅-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia
Autor:
Joanna M, Wierońska, Natalia, Kłeczek, Monika, Woźniak, Piotr, Gruca, Magdalena, Łasoń-Tyburkiewicz, Mariusz, Papp, Piotr, Brański, Grzegorz, Burnat, Andrzej, Pilc
Publikováno v:
Neurochemistry international. 88
Diverse preclinical studies exploiting the modulation of the GABAergic and/or glutamatergic system in brain via metabotropic receptors suggest their potential therapeutic utility. GS39783 and CDPPB, positive allosteric modulators of GABAB and mGlu5 r
Autor:
Joanna M. Wierońska, Andrzej Pilc, Anna Sławińska, Piotr Gruca, Mariusz Papp, Francine Acher, Magdalena Łasoń-Tyburkiewicz
Rationale Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new way to achieve antipsychotic-like activity. LSP1-2111, the group III mGlu receptor orthosteric agonist, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f665419d068949b501a119b5e95d79
https://ruj.uj.edu.pl/xmlui/handle/item/106082
https://ruj.uj.edu.pl/xmlui/handle/item/106082
Publikováno v:
Pharmacological reports : PR. 62(6)
A conditioned place preference paradigm was used to assess potential rewarding properties of melatonin. The conditioning with melatonin was carried out at two periods of the 12-h light/dark cycle: in the morning (08.30-10.00) and in the evening (18.3
Autor:
Magdalena Łasoń-Tyburkiewicz, Dario Doller, Andrzej Pilc, Joanna M. Wierońska, Piotr Gruca, Mariusz Papp
Publikováno v:
Pharmacological Reports. 64:486