Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Magdalena, Uhart"'
Autor:
Mary Elliott, Dirk J. Blom, Ransi Somaratne, Handrean Soran, Magdalena Uhart, David Preiss, Peter P. Toth, Michael J. Koren, Marcoli Cyrille, Naveed Sattar
Statin therapy modestly increases new-onset diabetes risk. The effect of proprotein convertase subtilisin/kexin type 9 inhibition on new-onset diabetes, glycemia, and weight remains unclear. We studied the effects of the proprotein convertase subtili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f6c6afd2536a69d5983d6ab42cf9a7
https://eprints.gla.ac.uk/147567/7/147567.pdf
https://eprints.gla.ac.uk/147567/7/147567.pdf
Autor:
Takako Araki, Svetlana Zonis, Cuiqi Zhou, Michael J. Workman, Shlomo Melmed, Vladimir A. Ljubimov, Robert Barrett, Vera Chesnokova, Maria Victoria Recouvreux, Kolja Wawrowsky, Anat Ben-Shlomo, Magdalena Uhart
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 23
Growth hormone (GH) excess in acromegaly is associated with increased precancerous colon polyps and soft tissue adenomas, whereas short-stature humans harboring an inactivating GH receptor mutation do not develop cancer. We show that locally expresse
Autor:
Xiuqing Guo, Henry R. Kranzler, Ning Li, Xiaofei Yan, Gary S. Wand, Mary E. McCaul, Magdalena Uhart, Elise M. Weerts
Publikováno v:
Addiction Biology. 18:357-369
Background Individual differences in subjective responses to alcohol (SR) are moderated by genetic variants and may be risk factors for the development of alcohol use disorders. Variation in the GABAA α2 receptor subunit gene (GABRA2) has been assoc
Autor:
Jack Samuels, Virginia L. Willour, Paul T. Costa, Magdalena Uhart, Irving M. Reti, Gerald Nestadt, Jerry Z. Xu, Oscar J. Bienvenu, Yu Jen Cheng, Laura Kasch-Semenza, Jason Yanofski, Karen Bandeen-Roche, Jodi B. A. McKibben, William W. Eaton, Peter P. Zandi
Publikováno v:
Comprehensive Psychiatry, Vol 52, Iss 2, Pp 188-194 (2011)
Objective Preclinical and human family studies clearly link monoamine oxidase A (MAOA) to aggression and antisocial personality (ASP). The 30–base pair variable number tandem repeat in the MAOA promoter regulates MAOA levels, but its effects on ASP
Autor:
Alene F. Carteret, Cheryl Carmona, James N. Campbell, Magdalena Uhart, Robert R. Edwards, Gary S. Wand, J. James Frost, Yu Kyeong Kim, Claudia M. Campbell
Publikováno v:
Pain. 141:114-118
Though it is clear that genomic variability plays an integral role in accounting for pain sensitivity, controversy exists over which genes are involved. While recent data suggest a "protective" (i.e., less pain) haplotype in the GTP cyclohydrolase (G
Autor:
Gary S. Wand, Magdalena Uhart
Publikováno v:
Addiction Biology. 14:43-64
A challenging question that continues unanswered in the field of addiction is why some individuals are more vulnerable to substance use disorders than others. Numerous risk factors for alcohol and other drugs of abuse, including exposure to various f
Publikováno v:
Psychoneuroendocrinology. 31:642-652
The present study was designed to determine whether there are gender differences in hormonal response patterns to HPA axis activation. To this end, two methods of activating the HPA axis were employed: a standardized psychological stress test and a p
Publikováno v:
Alcohol Research : Current Reviews
Understanding the biologic systems that underlie the relationship between stress and alcohol consumption may lead to better prevention efforts and more effective treatments for alcoholism. Clinical laboratory studies offer a unique opportunity to exa
Autor:
Yuna Wu, Peter P. Toth, Constantine Djedjos, Erik Stroes, Scott M. Wasserman, Magdalena Uhart, Michelle Geller, Robert Giugliano, Ransi Somaratne, Dirk Blom, Ricardo Dent, Marc Sabatine
Publikováno v:
Journal of the American College of Cardiology. 67:1868
Evolocumab, a fully human monoclonal antibody to PCSK9, can reduce LDL-C to very low (VL) levels. We assessed the safety of VL LDL-C by analyzing data from a pooled analysis of patients in evolocumab phase 2 or 3 randomized and placebo/comparator-con