Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Magdalena, Sternak"'
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100355- (2023)
Biogenesis of lipid droplets (LDs) in various cells plays an important role in various physiological and pathological processes. However, the function of LDs in endothelial physiology and pathology is not well understood. In the present work, we inve
Externí odkaz:
https://doaj.org/article/b4af39a67ab14397b5cc88df68e71423
Autor:
Marta Smeda, Agnieszka Jasztal, Ebrahim H Maleki, Anna Bar, Magdalena Sternak, Grzegorz Kwiatkowski, Joanna Suraj-Prażmowska, Bartosz Proniewski, Anna Kieronska-Rudek, Kamila Wojnar-Lason, Klaudia Skrzypek, Marcin Majka, Karolina Chrabaszcz, Kamilla Malek, Stefan Chlopicki
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Ageing is a major risk factor for cancer metastasis but the underlying mechanisms remain unclear. Here, we characterised ageing effects on cancer-induced endothelial-mesenchymal transition (EndMT) in the pulmonary circulation of female BALB/c mice in
Externí odkaz:
https://doaj.org/article/1315e1516b4f4e04b3a57d66dec1f459
Autor:
Marta Smeda, Marta Stojak, Kamil Przyborowski, Magdalena Sternak, Joanna Suraj-Prazmowska, Kamil Kus, Katarzyna Derszniak, Agnieszka Jasztal, Agnieszka Kij, Anna Kurpinska, Anna Kieronska-Rudek, Kamila Wojnar-Lason, Elzbieta Buczek, Tasnim Mohaissen, Stefan Chlopicki
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Activation of the coagulation cascade favours metastatic spread, but antithrombotic therapy might also have detrimental effects on cancer progression. In this study, we characterized the effects of dabigatran, a direct reversible thrombin inhibitor,
Externí odkaz:
https://doaj.org/article/ed5f7afb64734566845378aec5aeab9d
Autor:
Marta Smeda, Agnieszka Kij, Bartosz Proniewski, Karolina Matyjaszczyk-Gwarda, Kamil Przyborowski, Agnieszka Jasztal, Katarzyna Derszniak, Piotr Berkowicz, Anna Kieronska-Rudek, Marta Stojak, Magdalena Sternak, Stefan Chlopicki
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230520 (2020)
Long-term administration of acetylsalicylic acid (ASA) was effective in prevention of colorectal cancer, whereas the efficacy of this compound in other cancer types, including breast cancer, has been less convincingly documented. Indeed, the antimeta
Externí odkaz:
https://doaj.org/article/55ce6137b7104fe780b7a46b7081604a
Autor:
Marta Smeda, Anna Kieronska, Mateusz G. Adamski, Bartosz Proniewski, Magdalena Sternak, Tasnim Mohaissen, Kamil Przyborowski, Katarzyna Derszniak, Dawid Kaczor, Marta Stojak, Elzbieta Buczek, Agnieszka Jasztal, Joanna Wietrzyk, Stefan Chlopicki
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background Mesenchymal transformation of pulmonary endothelial cells contributes to the formation of a metastatic microenvironment, but it is not known whether this precedes or follows early metastasis formation. In the present work, we char
Externí odkaz:
https://doaj.org/article/daf84c367bab4c1382cbd0e05023bc42
Autor:
Joanna Suraj, Anna Kurpińska, Agnieszka Zakrzewska, Magdalena Sternak, Marta Stojak, Agnieszka Jasztal, Maria Walczak, Stefan Chlopicki
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 3 (2019)
The endothelium plays an important role in cancer metastasis, but the mechanisms involved are still not clear. In the present work, we characterised the changes in endothelial function at early and late stages of breast cancer progression in an ortho
Externí odkaz:
https://doaj.org/article/609653769f904f199347a40bba32573b
Autor:
Anna Bar, Marta Targosz‐Korecka, Joanna Suraj, Bartosz Proniewski, Agnieszka Jasztal, Brygida Marczyk, Magdalena Sternak, Magdalena Przybyło, Anna Kurpińska, Maria Walczak, Renata B. Kostogrys, Marek Szymonski, Stefan Chlopicki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 6 (2019)
Background The impairment of endothelium‐dependent vasodilation, increased endothelial permeability, and glycocalyx degradation are all important pathophysiological components of endothelial dysfunction. However, it is still not clear whether in at
Externí odkaz:
https://doaj.org/article/7cac866c1c344b28b6e1e5be01a993c2
Autor:
Krzysztof Czamara, Zuzanna Majka, Magdalena Sternak, Mateusz Koziol, Renata B. Kostogrys, Stefan Chlopicki, Agnieszka Kaczor
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4838 (2020)
Fiber optic Raman spectroscopy and Raman microscopy were used to investigate alterations in the aorta wall and the surrounding perivascular adipose tissue (PVAT) in the murine model of atherosclerosis (Apoe-/-/Ldlr-/- mice). Both abdominal and thorac
Externí odkaz:
https://doaj.org/article/df85e68c69e2492ab3061dba294257ef
Autor:
Magdalena Sternak, Anna Bar, Mateusz G. Adamski, Tasnim Mohaissen, Brygida Marczyk, Anna Kieronska, Marta Stojak, Kamil Kus, Antoine Tarjus, Frederic Jaisser, Stefan Chlopicki
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The role of epithelial sodium channel (ENaC) activity in the regulation of endothelial function is not clear. Here, we analyze the role of ENaC in the regulation of endothelium-dependent vasodilation and endothelial permeability in vivo in mice with
Externí odkaz:
https://doaj.org/article/843045c853f344af8c38010131a56f08
Autor:
Mateusz G. Adamski, Magdalena Sternak, Tasnim Mohaissen, Dawid Kaczor, Joanna M. Wierońska, Monika Malinowska, Iwona Czaban, Katarzyna Byk, Kristina S. Lyngsø, Kamil Przyborowski, Pernille B.L. Hansen, Grzegorz Wilczyński, Stefan Chlopicki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 7 (2018)
BackgroundAlthough advanced heart failure (HF) is a clinically documented risk factor for vascular cognitive impairment, the occurrence and pathomechanisms of vascular cognitive impairment in early stages of HF are equivocal. Here, we characterize va
Externí odkaz:
https://doaj.org/article/b7c4a58aea5d4c42b9545c59acc5bee1