Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Magdalena, Orzechowska"'
Autor:
Mateusz Bilski, Marzanna Ciesielka, Magdalena Orzechowska, Bożena Jarosz, Paulina Całka, Sylwia Bilska, Agata Banach, Gabriela Czaja, Jacek Fijuth, Łukasz Kuncman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Gliomas are the predominant cause of cancer-related deaths among the young population. Even after incorporation of IDH1/2 mutations and 1p19q codeletion there are doubts regarding adjuvant treatment in WHO G2/G3 gliomas. miRNA molecules cont
Externí odkaz:
https://doaj.org/article/b7f3a899db824a89aa852940bab59e8d
Publikováno v:
Molecular Oncology, Vol 18, Iss 5, Pp 1316-1326 (2024)
Most of the currently used cancer immunotherapies inhibit the programmed cell death protein 1 (PD1)–programmed cell death 1 ligand 1 (PDL1) axis of T‐cells. However, dendritic cells (DCs) controlled by natural killer (NK) cells via the FMS‐rela
Externí odkaz:
https://doaj.org/article/c5d4c890e20041f9acaca89bcc4b2de8
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 1395-1415 (2023)
Background: Cellular metabolism is a tightly controlled process during which cell growth and survival are maintained. Lung cancer is a disease with clear sex differences, where female patients have better survival rates than males. Evidence of sex di
Externí odkaz:
https://doaj.org/article/2e94ad0a62094ac589842c7b1444eea6
Autor:
Damian Kołat, Żaneta Kałuzińska-Kołat, Katarzyna Kośla, Magdalena Orzechowska, Elżbieta Płuciennik, Andrzej K. Bednarek
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: The discovery of non-coding RNA (ncRNA) dates back to the pre-genomics era, but the progress in this field is still dynamic and leverages current post-genomics solutions. WWOX is a global gene expression modulator that is scarcely inves
Externí odkaz:
https://doaj.org/article/d63a6de530c54cc5a805463a8d62a78c
Autor:
Jakub Kopeć, Elżbieta Sałacińska-Łoś, Magdalena Orzechowska, Monika Sokolnicka, Aleksandra Gawłowska-Marciniak, Przewratil Przemysław
Publikováno v:
Diagnostics, Vol 14, Iss 1, p 38 (2023)
Background: Vascular anomalies often result in aesthetic flaws, pain, and impair the quality of life. They require challenging treatments that frequently do not provide the desired results. The mammalian target of rapamycin (mTOR) is directly involve
Externí odkaz:
https://doaj.org/article/ef67318ec9e4466786c49ef9469211ae
Autor:
Żaneta Kałuzińska, Damian Kołat, Katarzyna Kośla, Magdalena Orzechowska, Andrzej K. Bednarek, Elżbieta Płuciennik
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background WW Domain Containing Oxidoreductase (WWOX) belongs to the unusual tumor suppressors, whose molecular function is not fully understood in bladder cancer, especially regarding interaction with Activator Protein 2 (AP-2) α/γ transc
Externí odkaz:
https://doaj.org/article/bc7a5d82aa04400dac127af68b626f54
Autor:
Dominika Oziębło, Marcin L. Leja, Aldona Jeznach, Magdalena Orzechowska, Tomasz Skirecki, Ewa Więsik-Szewczyk, Mariusz Furmanek, Natalia Bałdyga, Henryk Skarżyński, Monika Ołdak
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The NLRP3 gene mutations are the cause of autosomal dominant autoinflammatory disorders (NLRP3-AID). Recently, hearing loss (HL) has been found to be the sole or major manifestation of NLRP3-AID. Here, we tested 110 autosomal dominant HL families wit
Externí odkaz:
https://doaj.org/article/060c1f0a74764af0865408e9be4f4718
Autor:
Damian Kołat, Żaneta Kałuzińska, Magdalena Orzechowska, Andrzej K. Bednarek, Elżbieta Płuciennik
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Among all causes of death, cancer is the most prevalent and is only outpaced by cardiovascular diseases. Molecular theory of carcinogenesis states that apoptosis and proliferation are regulated by groups of tumor suppressors or on
Externí odkaz:
https://doaj.org/article/214a6f0cd848484d954623c2216f4470
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Breast cancer (BC) remains a significant healthcare challenge. Routinely, the treatment strategy is determined by immunohistochemistry (IHC)-based assessment of the key proteins such as estrogen receptor (ER), progesterone receptor (PR), human epider
Externí odkaz:
https://doaj.org/article/da0953049714428ab10fe2f92b5fe89a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The Notch pathway involves evolutionarily conserved signaling regulating the development of the female tract organs such as breast, ovary, cervix, and uterine endometrium. A great number of studies revealed Notch aberrancies in association with their
Externí odkaz:
https://doaj.org/article/4498789d35b8496bbbb740b6943cedfb