Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Magdalena, Minnion"'
Autor:
Ahilanandan Dushianthan, Paul Mouncey, Daniel Martin, Lamprini Lampro, Tasnin Shahid, Victoria Goss, Amelia Francis Johnson, William Herbert, Angelica Cazley, Mark Lamond, William Jones, Karen Salmon, Florence Neyroud, Magdalena Minnion, Julian Lentaigne, Grielof Koster, Madhuri Panchal, Anthony D Postle, Helen Moyses, Michael P W Grocott, Martin Feelisch
Publikováno v:
NIHR Open Research, Vol 4 (2024)
Background MecROX is a mechanistic sub-study of the UK-ROX trial which was designed to evaluate the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care. This is based on the
Externí odkaz:
https://doaj.org/article/2d78ef0bea914040a6d45e0af39db2f2
Autor:
Tim J. M. Wallis, Magdalena Minnion, Anna Freeman, Andrew Bates, James M. Otto, Stephen A. Wootton, Sophie V. Fletcher, Michael P. W. Grocott, Martin Feelisch, Mark G. Jones, Sandy Jack
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1645 (2023)
Exercise training is recommended for patients with idiopathic pulmonary fibrosis (IPF); however, the mechanism(s) underlying its physiological benefits remain unclear. We investigated the effects of an individualised aerobic interval training program
Externí odkaz:
https://doaj.org/article/6b618fa1066149759942b5ce2127fa80
Autor:
Renato C. Nogueira, Magdalena Minnion, Anna D. Clark, Alex Dyson, José E. Tanus-Santos, Martin Feelisch
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102362- (2022)
In blood, the majority of endothelial nitric oxide (NO) is scavenged by oxyhemoglobin, forming nitrate while a small part reacts with dissolved oxygen to nitrite; another fraction may bind to deoxyhemoglobin to generate nitrosylhemoglobin (HbNO) and/
Externí odkaz:
https://doaj.org/article/f4505a5ce6cf4b2eaadf587083c5642e
Autor:
Amanda M. L. Rhodes, Sehrish Ali, Magdalena Minnion, Ling H. Lee, Brijil M. Joseph, Judwin Ndzo, Nicholas M. P. Clarke, Martin Feelisch, Alexander Aarvold
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 538 (2023)
Developmental dysplasia of the hip (DDH) is the most prevalent congenital musculoskeletal disorder, yet its cause remains unknown. Adequate nutrient provision and coordinated electron exchange (redox) processes are critical for foetal growth and tiss
Externí odkaz:
https://doaj.org/article/eca669d6097f4119bbdc4cc261a0317d
Autor:
Helen T. McKenna, Katie A. O'Brien, Bernadette O. Fernandez, Magdalena Minnion, Adam Tod, Ben D. McNally, James A. West, Julian L. Griffin, Michael P. Grocott, Michael G. Mythen, Martin Feelisch, Andrew J. Murray, Daniel S. Martin
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101907- (2021)
Background: Numerous pathologies result in multiple-organ failure, which is thought to be a direct consequence of compromised cellular bioenergetic status. Neither the nature of this phenotype nor its relevance to survival are well understood, limiti
Externí odkaz:
https://doaj.org/article/9c66267adf404de2a8e691584df51551
Autor:
Kenneth R. Olson, Austin Briggs, Monesh Devireddy, Nicholas A. Iovino, Nicole C. Skora, Jenna Whelan, Brian P. Villa, Xiaotong Yuan, Varun Mannam, Scott Howard, Yan Gao, Magdalena Minnion, Martin Feelisch
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101731- (2020)
Matcha and green tea catechins such as (−)-epicatechin (EC), (−)-epigallocatechin (EGC) and (−)-epigallocatechin gallate (EGCG) have long been studied for their antioxidant and health-promoting effects. Using specific fluorophores for H2S (AzMC
Externí odkaz:
https://doaj.org/article/fef26bf76cf14328b53c8e8215713d9b
Autor:
Anna Freeman, Doriana Cellura, Magdalena Minnion, Bernadette O. Fernandez, Cosma Mirella Spalluto, Denny Levett, Andrew Bates, Timothy Wallis, Alastair Watson, Sandy Jack, Karl J. Staples, Michael P. W. Grocott, Martin Feelisch, Tom M. A. Wilkinson
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1926 (2021)
Redox dysregulation and oxidative stress have been implicated in asthma pathogenesis. Exercise interventions improve symptoms and reduce inflammation in asthma patients, but the underlying mechanisms remain unclear. We hypothesized that a personalise
Externí odkaz:
https://doaj.org/article/6966a5e69d804666a0b1f3956220dc2a
Autor:
Andrew F. Cumpstey, Magdalena Minnion, Bernadette O. Fernandez, Monika Mikus-Lelinska, Kay Mitchell, Daniel S. Martin, Michael P.W. Grocott, Martin Feelisch
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
The chemical and functional interactions between Reactive Oxygen (ROS), Nitrogen (RNS) and Sulfur (RSS) species allow organisms to detect and respond to metabolic and environmental stressors, such as exercise and altitude exposure. Whether redox mark
Externí odkaz:
https://doaj.org/article/4f44156f38eb4800a340f8f913540863
Autor:
Fieke Terstappen, Sinéad M. Clarke, Jaap A. Joles, Courtney A Ross, Michael R. Garrett, Magdalena Minnion, Martin Feelisch, Harry van Goor, Jennifer M. Sasser, A. Titia Lely
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 302 (2020)
Aberrant production of hydrogen sulfide (H2S) has been linked to preeclampsia. We hypothesized that sodium thiosulfate (STS), a H2S donor, reduces hypertension and proteinuria, and diminishes fetal growth restriction in the Dahl salt-sensitive (S) ra
Externí odkaz:
https://doaj.org/article/98ae780af3034a358f44e24492c6e4dc
Autor:
Sonam Gurung, Oskar V. Timmermand, Dany Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Abigail R. Barber, Richard S. Edwards, Patrick F. Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G.V. Martini, Philippa B. Mills, Simon N. Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H. Witney, Julien Baruteau
Argininosuccinate lyase (ASL) is a key enzyme integral to the hepatic urea cycle which is required for ammonia detoxification, and the citrulline-nitric oxide (NO) cycle for NO production. ASL deficient patients present with argininosuccinic aciduria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8192b71655c57665732e2f7516f7ad84
https://doi.org/10.1101/2022.10.19.512931
https://doi.org/10.1101/2022.10.19.512931
