Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Magdalena, Huber"'
Autor:
Tim Böttrich, Pascal Bauer, Vincent Gröβer, Magdalena Huber, Hartmann Raifer, Torsten Frech, Svenja Nolte, Theresa Dombrowski, Franz Cemic, Natascha Sommer, Robert Ringseis, Klaus Eder, Karsten Krüger, Christopher Weyh
Publikováno v:
Journal of Sport and Health Science, Vol 13, Iss 3, Pp 288-296 (2024)
Background: Atherosclerosis forms the pathological basis for the development of cardiovascular disease. Since pathological processes initially develop without clinically relevant symptoms, the identification of early markers in the subclinical stage
Externí odkaz:
https://doaj.org/article/e58ccd71a67e46b5b75615be62a8c963
Autor:
Clara Simon, Inka D Brunke, Bastian Stielow, Ignasi Forné, Anna Mary Steitz, Merle Geller, Iris Rohner, Lisa Marie Weber, Sabrina Fischer, Lea Marie Jeude, Theresa Huber, Andrea Nist, Thorsten Stiewe, Magdalena Huber, Malte Buchholz, Robert Liefke
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002739 (2024)
Pancreatic ductal adenocarcinoma (PDAC) poses a significant threat due to its tendency to evade early detection, frequent metastasis, and the subsequent challenges in devising effective treatments. Processes that govern epithelial-mesenchymal transit
Externí odkaz:
https://doaj.org/article/0154901bedc94acf98fd143354555040
T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms
Autor:
Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian B. Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl, Ingo Burtscher, Sonja Dehnert, Chege Kuria, Alexandra Kupke, Stephanie Paul, Thomas Liehr, Marcus Lechner, Markus Schnare, Andreas Kaufmann, Magdalena Huber, Thomas H. Winkler, Stefan Bauer, Philipp Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their function as anti-cancer immune targets or drivers of autoimmune disease. Here, we genera
Externí odkaz:
https://doaj.org/article/614f814272ae48b086e1c7fdf428b850
Autor:
Janessa Hofeichner, Bernd Martin Gahr, Magdalena Huber, Alena Boos, Wolfgang Rottbauer, Steffen Just
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Nexilin (NEXN) plays a crucial role in stabilizing the sarcomeric Z-disk of striated muscle fibers and, when mutated, leads to dilated cardiomyopathy in humans. Due to its early neonatal lethality in mice, the detailed impact of the constitu
Externí odkaz:
https://doaj.org/article/e08620d4a73f433e931fbe5cc9844ed3
Autor:
Felix Neuhaus, Sonja Lieber, Veronika Shinkevich, Anna Mary Steitz, Hartmann Raifer, Kathrin Roth, Florian Finkernagel, Thomas Worzfeld, Andreas Burchert, Corinna Keber, Andrea Nist, Thorsten Stiewe, Silke Reinartz, Vanessa M. Beutgen, Johannes Graumann, Kim Pauck, Holger Garn, Matthias Gaida, Rolf Müller, Magdalena Huber
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Abstract Background IL‐17A and TNF synergistically promote inflammation and tumorigenesis. Their interplay and impact on ovarian carcinoma (OC) progression are, however, poorly understood. We addressed this question focusing on mesothelial cells, w
Externí odkaz:
https://doaj.org/article/34a4cb60682e4aa7997d2f9cd82ee079
Autor:
Anna Mary Steitz, Clarissa Schröder, Isabel Knuth, Corinna U. Keber, Leah Sommerfeld, Florian Finkernagel, Julia M. Jansen, Uwe Wagner, Sabine Müller-Brüsselbach, Thomas Worzfeld, Magdalena Huber, Vanessa M. Beutgen, Johannes Graumann, Elke Pogge von Strandmann, Rolf Müller, Silke Reinartz
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108401- (2023)
Summary: A crucial requirement for metastasis formation in ovarian high-grade serous carcinoma (HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems of primary human cells, we discovered that tumor-associated NK
Externí odkaz:
https://doaj.org/article/e9c08e3135684fc89cfce67f8891a099
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/7e1f900e4a0f4af8aee7ba1090beabf3
Autor:
Jefferson Antônio Leite, Luísa Menezes, Eloisa Martins, Tamara Silva Rodrigues, Lucas Tavares, Anna Ebering, Carsten Schelmbauer, Guilherme C. Martelossi Cebinelli, Valeriya Zinina, Artemiy Golden, Natalia Soshnikova, Dario S. Zamboni, Fernando Q. Cunha, Magdalena Huber, João Santana Silva, Ari Waisman, Daniela Carlos, Niels Olsen Saraiva Câmara
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108134- (2023)
Summary: AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA sensor. Recent studies have highlighted AIM2’s function on regulatory T cells (Treg) and follicular T ce
Externí odkaz:
https://doaj.org/article/4aa4b8055f9049c997033944049dce04
Autor:
Jana Palmowski, Sarah Kohnhorst, Pascal Bauer, Christian Puta, Simon Haunhorst, Kristina Gebhardt, Thomas Reichel, Christian Keller, Magdalena Huber, Hartmann Raifer, Karsten Krüger
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Guidelines for medical clearing after SARS-CoV-2 infection in elite athletes do not include T-cell immunity aspects despite its relevance in the course of COVID-19 disease. Therefore, we aimed to analyze T-cell-related cytokines before and after in-v
Externí odkaz:
https://doaj.org/article/977d2ee5b76d4bab93bdbed290e7a044
Autor:
Tamara Kaleta, Lisa Kern, Samuel Leandro Hong, Martin Hölzer, Georg Kochs, Julius Beer, Daniel Schnepf, Martin Schwemmle, Nena Bollen, Philipp Kolb, Magdalena Huber, Svenja Ulferts, Sebastian Weigang, Gytis Dudas, Alice Wittig, Lena Jaki, Abdou Padane, Adamou Lagare, Mounerou Salou, Egon Anderson Ozer, Ndodo Nnaemeka, John Kofi Odoom, Robert Rutayisire, Alia Benkahla, Chantal Akoua-Koffi, Abdoul-Salam Ouedraogo, Etienne Simon-Lorière, Vincent Enouf, Stefan Kröger, Sébastien Calvignac-Spencer, Guy Baele, Marcus Panning, Jonas Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The A.27 SARS-CoV-2 lineage spread globally in 2021 but did not become dominant. Here, the authors show that A.27 shares some mutations in the spike gene that are present in variants of concern, but lacks the D614G mutation, indicating independent ev
Externí odkaz:
https://doaj.org/article/95413bc995ee4d938afb0a7f4c3cfaa7