Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Magda S Santos"'
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109824 (2014)
Exocytotic release of glutamate depends upon loading of the neurotransmitter into synaptic vesicles by vesicular glutamate transporters, VGLUTs. The major isoforms, VGLUT1 and 2, exhibit a complementary pattern of expression in synapses of the adult
Externí odkaz:
https://doaj.org/article/c56dbae7ef434f348c8e4e7baa1930a9
Autor:
Cristina Martins-Silva, Xavier De Jaeger, Monica S Guzman, Ricardo D F Lima, Magda S Santos, Christopher Kushmerick, Marcus V Gomez, Marc G Caron, Marco A M Prado, Vania F Prado
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17611 (2011)
Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly because of the difficulty in generating suitable animal models of cholinergic dysfunction. We have recently shown that, by targeting the vesicular acetylcho
Externí odkaz:
https://doaj.org/article/4ac73b1ec9294da192a0874c76d99dd4
Autor:
Marwan Shinawi, Malay A. Phoong, Angela E. Scheuerle, Susan M. Voglmaier, Nitin Khandelwal, Magda S. Santos, Elliott H. Sherr, Roxanne Simmons, Ege T. Kavalali, Michael Chez, Ruiji Jiang, Haiyan Li, Bethany Smith-Packard, Kendall C. Parks, Shaun A. Hussain, Audrey Cortesi, Baris Alten, Brianna M. Paul, Sanam J. Lalani, Heather G. Fisher
Publikováno v:
Human Mutation. 41:1999-2011
Clinical and genetic features of five unrelated patients with de novo pathogenic variants in the synaptic vesicle-associated membrane protein 2 (VAMP2) reveal common features of global developmental delay, autistic tendencies, behavioral disturbances
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Release of the major excitatory neurotransmitter glutamate by synaptic vesicle exocytosis depends on glutamate loading into synaptic vesicles by vesicular glutamate transporters (VGLUTs). The two principal isoforms, VGLUT1 and 2, exhibit a complement
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 33, iss 26
The vesicular glutamate transporters (VGLUTs) package glutamate into synaptic vesicles, and the two principal isoforms VGLUT1 and VGLUT2 have been suggested to influence the properties of release. To understand how a VGLUT isoform might influence tra
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 33, iss 26
Increasing evidence indicates that individual synaptic vesicle proteins may use different signals, endocytic adaptors, and trafficking pathways for sorting to distinct pools of synaptic vesicles. Here, we report the identification of a unique amino a
Publikováno v:
Neuroscience. 158:189-203
Expression of the integral and associated proteins of synaptic vesicles is subject to regulation over time, by region, and in response to activity. The process by which changes in protein levels and isoforms result in different properties of neurotra
Autor:
Eduardo Candelario-Jalil, Antônio Carlos Pinheiro de Oliveira, Bernd L. Fiebich, Helton José Reis, Magda S. Santos, András Palotás
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
For many years, the brain had been regarded as an immune-privileged organ because of an old tenet which stated that no classical immune activation or inflammation could take place intrathecally. However, this theory has quickly changed with the adven
Autor:
Marco A. M. Prado, Cristina Martins-Silva, Stephen S. G. Ferguson, Marcus Vinicius Gomez, Lucimar T. Ferreira, Magda S. Santos, J. Barbosa, Marc G. Caron, Vania F. Prado, Gonzalo E. Torres
Publikováno v:
Journal of Neurochemistry. 82:1221-1228
The pathways by which synaptic vesicle proteins reach their destination are not completely defined. Here we investigated the traffic of a green fluorescent protein (GFP)-tagged version of the vesicular acetylcholine transporter (VAChT) in cholinergic
Visualization and Trafficking of the Vesicular Acetylcholine Transporter in Living Cholinergic Cells
Autor:
Magda S. Santos, Vania F. Prado, Christopher Kushmerick, J. Barbosa, Marco A. M. Prado, Marcus Vinicius Gomez
Publikováno v:
Journal of Neurochemistry. 74:2425-2435
The present experiments investigated the trafficking of the vesicular acetylcholine transporter (VAChT) tagged with the enhanced green fluorescent protein (EGFP) in living cholinergic cells (SN56). The EGFP-VAChT chimera was located in endosomal-like