Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Magda R. Hamczyk"'
Autor:
Magda R. Hamczyk, Vicente Andrés
Publikováno v:
Nucleus, Vol 10, Iss 1, Pp 48-54 (2019)
Lamin A, a product of the LMNA gene, is an essential nuclear envelope component in most differentiated cells. Mutations in LMNA have been linked to premature aging disorders, including Hutchinson-Gilford progeria syndrome (HGPS). HGPS is caused by pr
Externí odkaz:
https://doaj.org/article/f44fdf8a65c245f1b6a1e4410d172064
Publikováno v:
Cells, Vol 9, Iss 10, p 2252 (2020)
Hutchinson–Gilford progeria syndrome (HGPS) is among the most devastating of the laminopathies, rare genetic diseases caused by mutations in genes encoding nuclear lamina proteins. HGPS patients age prematurely and die in adolescence, typically of
Externí odkaz:
https://doaj.org/article/916c15b0db634249ba9b9d708475498d
Autor:
Magda R Hamczyk, Ricardo Villa‐Bellosta, Víctor Quesada, Pilar Gonzalo, Sandra Vidak, Rosa M Nevado, María J Andrés‐Manzano, Tom Misteli, Carlos López‐Otín, Vicente Andrés
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 4, Pp 1-13 (2019)
Abstract Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder caused by progerin, a mutant lamin A variant. HGPS patients display accelerated aging and die prematurely, typically from atherosclerosis complications. Recently, we de
Externí odkaz:
https://doaj.org/article/90fa5e8960124fb793cbbc7fdd07bf46
Autor:
Magda R. Hamczyk, Rosa M. Nevado
Publikováno v:
Clínica e Investigación en Arteriosclerosis (English Edition). 35:42-51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf8294df4d0e047782b94716b8d8382a
https://doi.org/10.1016/j.artere.2023.02.005
https://doi.org/10.1016/j.artere.2023.02.005
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174998 (2017)
PURPOSE:Phosphorus is an essential nutrient involved in many pathobiological processes. Less than 1% of phosphorus is found in extracellular fluids as inorganic phosphate ion (Pi) in solution. High serum Pi level promotes ectopic calcification in man
Externí odkaz:
https://doaj.org/article/01c0bc8cd19f4ed29d278dfafdeccae9
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2419
Aging is associated with alterations in the arterial wall that promote vascular disease development and its clinical manifestations, including myocardial infarction, stroke, and arterial dissection. The arterial wall is comprised of three layers, int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cb02669ecd1c6c6a356a2d4da1998b1
https://pubmed.ncbi.nlm.nih.gov/35237992
https://pubmed.ncbi.nlm.nih.gov/35237992
Publikováno v:
Journal of the American College of Cardiology. 75:919-930
Aging is the main risk factor for vascular disease and ensuing cardiovascular and cerebrovascular events, the leading causes of death worldwide. In a progressively aging population, it is essential to develop early-life biomarkers that efficiently id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257bdeb8d09959fcb4769ced8758f690
https://doi.org/10.1016/j.jacc.2019.11.062
https://doi.org/10.1016/j.jacc.2019.11.062
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21e67eaccee8af4136421516dbb11980
https://doi.org/10.1007/978-1-0716-1924-7_38
https://doi.org/10.1007/978-1-0716-1924-7_38
Autor:
Sussan Nourshargh, Loïc Rolas, María J. Andrés-Manzano, Beatriz Dorado, Víctor Fanjul, Ignacio Benedicto, Carla Espinós-Estévez, Pilar Gonzalo, Magda R. Hamczyk, Raquel Riquelme-Borja, Lara Del Campo, Jesús Vázquez, Alvaro Macias, Emilio Camafeita, Amanda Sánchez-López, Cristina González-Gómez, Anna Barkaway, Vicente Andrés
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized by premature aging and death mainly because of myocardial infarction, stroke, or heart failure. The d
Background: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized by premature aging and death mainly because of myocardial infarction, stroke, or heart failure. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b306bba104ae2c185182e39402ab1be
https://pubmed.ncbi.nlm.nih.gov/34694158
https://pubmed.ncbi.nlm.nih.gov/34694158
Autor:
Martine de Boer, Frank Rühle, Vicente Andrés, Leon J. De Windt, Erika Hilbold, Christian Bär, Jana-Charlotte Hegenbarth, Monika Stoll, Rosa M Nevado, Blanche Schroen, Leonie Martens, Dirk J. Duncker, Anne-Sophie Armand, Federica De Majo, Thomas Thum, Magda R. Hamczyk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118(36):e2022974118. National Academy of Sciences
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Genomic instability, the unresolved accumulation of DNA variants, is hypothesized as one of the contributors to the natural aging process. We assessed the frequency of unresolved DNA damage reaching the transcriptome of the murine myocardium during t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2bfad205c1fe062cc23760a694be55
https://cris.maastrichtuniversity.nl/en/publications/cb4a6312-19ed-49a3-b368-2108e21f0804
https://cris.maastrichtuniversity.nl/en/publications/cb4a6312-19ed-49a3-b368-2108e21f0804