Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Magda Negrão"'
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Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic Colorectal Cancer
Autor: Raquel Cruz-Duarte, Cátia Rebelo de Almeida, Magda Negrão, Afonso Fernandes, Paula Borralho, Daniel Sobral, Lina M. Gallego-Paez, Daniel Machado, João Gramaça, José Vílchez, Ana T. Xavier, Miguel Godinho Ferreira, Ana R. Miranda, Helder Mansinho, Maria J. Brito, Teresa R. Pacheco, Catarina Abreu, Ana Lucia-Costa, André Mansinho, Rita Fior, Luís Costa, Marta Martins
Publikováno v: Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 2022, pp.clincanres.1992.2021. ⟨10.1158/1078-0432.CCR-21-1992⟩
© 2022 The Authors; Published by the American Association for Cancer Research. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 International (CC BY-NC-ND)
Purpose: Cetuximab is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8c83eb18a02ddfbb46b4b0884da178
https://doi.org/10.1158/1078-0432.ccr-21-1992
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5
The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma
Autor: Pierre Bedossa, Magda Negrão, Jerome Raffenne, Jérôme Cros, Miguel Godinho Ferreira, Rita Fior, Nicolas Poté, Samira Laouirem, Valérie Paradis, Slimane Ait Si Ali, Miguel Albuquerque
Publikováno v: Liver International
Liver International, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
Liver International, Wiley-Blackwell, 2020, 40 (4), pp.956-967. ⟨10.1111/liv.14381⟩
Liver International, Wiley-Blackwell, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
International audience; BACKGROUND & AIMS:Vascular invasion is a major prognostic factor in hepatocellular carcinoma (HCC). We previously identified histone H4 acetylated at lysine 16 (H4K16ac), a histone modification involved in transcription activa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e294b1b9bdb0059bfff5011fe1fc0f
https://www.hal.inserm.fr/inserm-02532680
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6
Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo
Autor: Gonçalo Bernardes, Rita Fior, Miguel Godinho Ferreira, Magda Negrão, João Conde, Bruno Oliveira, Benjamin Stenton
Creating ways to control drug activation at specific tissues while sparing healthy tissues remains a major challenge. The administration of exogenous triggers offers the possibility for precise and traceless drug activation. However, ensuring localiz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33773ebd89883d9de52c3cb18ebeebfa
https://doi.org/10.26434/chemrxiv.7327904
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7
Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N -Propargyl Handles for Drug-Activation
Autor: João Conde, Rita Fior, Gonçalo J. L. Bernardes, Felipe S. S. Schneider, Magda Negrão, Bruno L. Oliveira, Josiel B. Domingos, Giovanni F. Caramori, Cátia Rebelo de Almeida, Carlos Cordeiro, Benjamin J Stenton, V B Unnikrishnan, Miguel Godinho Ferreira
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, 142 (24), pp.10869-10880. ⟨10.1021/JACS.0C01622⟩
Journal of the American Chemical Society, 2020, 142 (24), pp.10869-10880. ⟨10.1021/JACS.0C01622⟩
International audience; The ability to create ways to control drug activation at specific tissues while sparing healthy tissues remains a major challenge. The administration of exogenous target-specific triggers offers the potential for traceless rel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c64a5248ab9f1f500fc35a8813d8d9
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