Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Magda Liczmanska"'
Autor:
Magda Liczmanska, Michael H. Tatham, Barbara Mojsa, Ania Eugui-Anta, Alejandro Rojas-Fernandez, Adel F.M. Ibrahim, Ronald T. Hay
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112960- (2023)
Summary: The small ubiquitin-like modifier (SUMO) protease SENP6 disassembles SUMO chains from cellular substrate proteins. We use a proteomic method to identify putative SENP6 substrates based on increased apparent molecular weight after SENP6 deple
Externí odkaz:
https://doaj.org/article/f01633d461d14c478619856e26e9f9e0
Autor:
Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay
Publikováno v:
Journal of Cell Biology. 222
Acute Promyelocytic Leukemia is caused by expression of the oncogenic Promyelocytic Leukemia (PML)–Retinoic Acid Receptor Alpha (RARA) fusion protein. Therapy with arsenic trioxide results in degradation of PML-RARA and PML and cures the disease. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b838c2b7933d353cf342d4404059e47
https://doi.org/10.1083/jcb.202201027
https://doi.org/10.1083/jcb.202201027
Autor:
Emma Branigan, Ronald T. Hay, Magda Liczmanska, Lindsay Davidson, Barbara Mojsa, Michael H. Tatham
Publikováno v:
bioRxiv
To determine the role of SUMO modification in the maintenance of pluripotent stem cells we used ML792, a potent and selective inhibitor of SUMO Activating Enzyme. Treatment of human induced pluripotent stem cells with ML792 initiated changes associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5436c3b0086cc43af5cd96eab98152d5
https://doi.org/10.1101/2020.12.22.423944
https://doi.org/10.1101/2020.12.22.423944
Autor:
Barbara Mojsa, Michael H. Tatham, Lindsay Davidson, Magda Liczmanska, Jane E. Wright, Nicola Wiechens, Marek Gierlinski, Tom Owen-Hughes, Ronald T. Hay
Pluripotent stem cells represent a powerful system to identify the mechanisms governing cell fate decisions during early mammalian development. Covalent attachment of the Small Ubiquitin Like Modifier (SUMO) to proteins has emerged as an important fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::f27ef6d9170b1ab92ae510ef93a37301
https://zenodo.org/record/4733591
https://zenodo.org/record/4733591
Autor:
Ronald T. Hay, Lindsay Davidson, Magda Liczmanska, Emma Branigan, Barbara Mojsa, Michael H. Tatham
Publikováno v:
Molecular & Cellular Proteomics : MCP
To investigate the role of SUMO modification in the maintenance of pluripotent stem cells, we used ML792, a potent and selective inhibitor of SUMO Activating Enzyme. Treatment of human induced pluripotent stem cells with ML792 resulted in the loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24080892cfd007ed232a37337620ae0
https://doi.org/10.1016/j.mcpro.2021.100164
https://doi.org/10.1016/j.mcpro.2021.100164