Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Magalie Larcher"'
Autor:
Jing Liu, Daniela Ottaviani, Meriem Sefta, Céline Desbrousses, Elodie Chapeaublanc, Rosario Aschero, Nanor Sirab, Fabiana Lubieniecki, Gabriela Lamas, Laurie Tonon, Catherine Dehainault, Clément Hua, Paul Fréneaux, Sacha Reichman, Narjesse Karboul, Anne Biton, Liliana Mirabal-Ortega, Magalie Larcher, Céline Brulard, Sandrine Arrufat, André Nicolas, Nabila Elarouci, Tatiana Popova, Fariba Némati, Didier Decaudin, David Gentien, Sylvain Baulande, Odette Mariani, Florent Dufour, Sylvain Guibert, Céline Vallot, Livia Lumbroso-Le Rouic, Alexandre Matet, Laurence Desjardins, Guillem Pascual-Pasto, Mariona Suñol, Jaume Catala-Mora, Genoveva Correa Llano, Jérôme Couturier, Emmanuel Barillot, Paula Schaiquevich, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Lisa Golmard, Claude Houdayer, Hervé Brisse, Isabelle Bernard-Pierrot, Eric Letouzé, Alain Viari, Simon Saule, Xavier Sastre-Garau, François Doz, Angel M. Carcaboso, Nathalie Cassoux, Celio Pouponnot, Olivier Goureau, Guillermo Chantada, Aurélien de Reyniès, Isabelle Aerts, François Radvanyi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Retinoblastoma is the most frequent intraocular paediatric malignancy whose molecular basis remains poorly understood. Here, the authors perform multi-omic analysis and identify two subtypes; one in a cone differentiated state and one more aggressive
Externí odkaz:
https://doaj.org/article/92fda6743ce64715a5b5d4c807ca5ced
Autor:
Coralie Dorard, Charlène Estrada, Céline Barbotin, Magalie Larcher, Alexandra Garancher, Jessy Leloup, Friedrich Beermann, Manuela Baccarini, Celio Pouponnot, Lionel Larue, Alain Eychène, Sabine Druillennec
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The melanoma-driver mutations in NRAS and BRAF are mutually exclusive but the contribution of RAF signalling downstream of NRAS remains to be clarified. Here, using mouse models, the authors show specific roles of each member of the RAF family at dif
Externí odkaz:
https://doaj.org/article/3790148bc8624695bd1b7e49449d5c3a
Autor:
Morgane Morabito, Magalie Larcher, Florence MG Cavalli, Chloé Foray, Antoine Forget, Liliana Mirabal‐Ortega, Mamy Andrianteranagna, Sabine Druillennec, Alexandra Garancher, Julien Masliah‐Planchon, Sophie Leboucher, Abel Debalkew, Alessandro Raso, Olivier Delattre, Stéphanie Puget, François Doz, Michael D Taylor, Olivier Ayrault, Franck Bourdeaut, Alain Eychène, Celio Pouponnot
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 8, Pp n/a-n/a (2019)
Abstract Medulloblastoma (MB) is a pediatric tumor of the cerebellum divided into four groups. Group 3 is of bad prognosis and remains poorly characterized. While the current treatment involving surgery, radiotherapy, and chemotherapy often fails, no
Externí odkaz:
https://doaj.org/article/953a146597434510bae487e93455a269
Autor:
Agathe Valluet, Sabine Druillennec, Céline Barbotin, Coralie Dorard, Anne H. Monsoro-Burq, Magalie Larcher, Celio Pouponnot, Manuela Baccarini, Lionel Larue, Alain Eychène
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 774-780 (2012)
B-Raf and C-Raf kinases have emerged as critical players in melanoma. However, little is known about their role during development and homeostasis of the melanocyte lineage. Here, we report that knockout of B-raf and C-raf genes in this lineage resul
Externí odkaz:
https://doaj.org/article/87e3b144f5804b57be06e297b7455ca7
Autor:
Agathe Valluet, Isabelle Hmitou, Sabrina Davis, Sabine Druillennec, Magalie Larcher, Serge Laroche, Alain Eychène
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15272 (2010)
The B-raf proto-oncogene exerts essential functions during development and adulthood. It is required for various processes, such as placental development, postnatal nervous system myelination and adult learning and memory. The mouse B-raf gene encode
Externí odkaz:
https://doaj.org/article/54b5eadecc9c4e5e9a8fc7aca6189301
FigureS3 from AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Effect of the combination of treatments in preclinical high-risk HDMB03 models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0545bd0508683a13750c883231be19da
https://doi.org/10.1158/1078-0432.22477776
https://doi.org/10.1158/1078-0432.22477776
Autor:
Caroline Robert, Nicolas Dumaz, Alain Eychène, Stephan Vagner, Sabine Druillennec, Alexander M. Eggermont, Alain Spatz, Ludovic Lacroix, Lise Boussemart, Nyam Kamsu-Kom, Jocelyne André, Magalie Larcher, Alain Sarasin, David Malka, Jean-Charles Soria, Emilie Hollville, Janine Wechsler, Gorana Tomasic, Bernard Escudier, Christine Mateus, Jean Philippe Arnault
PDF file - 208K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b14c5740a026d255c8835730c846eba
https://doi.org/10.1158/1078-0432.22446047.v1
https://doi.org/10.1158/1078-0432.22446047.v1
Autor:
Caroline Robert, Nicolas Dumaz, Alain Eychène, Stephan Vagner, Sabine Druillennec, Alexander M. Eggermont, Alain Spatz, Ludovic Lacroix, Lise Boussemart, Nyam Kamsu-Kom, Jocelyne André, Magalie Larcher, Alain Sarasin, David Malka, Jean-Charles Soria, Emilie Hollville, Janine Wechsler, Gorana Tomasic, Bernard Escudier, Christine Mateus, Jean Philippe Arnault
Purpose: The emergence of skin tumors in patients treated with sorafenib or with more recent BRAF inhibitors is an intriguing and potentially serious event. We carried out a clinical, pathologic, and molecular study of skin lesions occurring in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b64f100253a531af17307af6e6bb76
https://doi.org/10.1158/1078-0432.c.6520631.v1
https://doi.org/10.1158/1078-0432.c.6520631.v1
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Legends for supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d79c3526e1c9de55d91a003816598a
https://doi.org/10.1158/1078-0432.22477770.v1
https://doi.org/10.1158/1078-0432.22477770.v1
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Purpose:Medulloblastoma is an important cause of mortality and morbidity in pediatric oncology. Here, we investigated whether the DNA repair inhibitor, AsiDNA, could help address a significant unmet clinical need in medulloblastoma care, by improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9da6f13b4476dea6cfe675e8466d02
https://doi.org/10.1158/1078-0432.c.6529755.v1
https://doi.org/10.1158/1078-0432.c.6529755.v1