Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Magalie Celton"'
Autor:
Thomas Milan, Magalie Celton, Karine Lagacé, Élodie Roques, Safia Safa-Tahar-Henni, Eva Bresson, Anne Bergeron, Josée Hebert, Soheil Meshinchi, Sonia Cellot, Frédéric Barabé, Brian T Wilhelm
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
Chromosomal translocations involving the KMT2A gene are among the most common genetic alterations found in pediatric acute myeloid leukemias although the molecular mechanisms that initiate the disease remain incompletely defined. To elucidate these i
Externí odkaz:
https://doaj.org/article/3445885ee65c44fbb194a0e4415018f5
Autor:
Sonia Cellot, Josée Hébert, Elodie Roques, Anne Bergeron, Frédéric Barabé, Brian T. Wilhelm, Safia Safa-Tahar-Henni, Eva Bresson, Soheil Meshinchi, Thomas Milan, Karine Lagacé, Magalie Celton
Publikováno v:
Haematologica
Chromosomal translocations involving the KMT2A gene are among the most common genetic alterations found in pediatric acute myeloid leukemias although the molecular mechanisms that initiate the disease remain incompletely defined. To elucidate these i
Autor:
É Roques, Julie Pelloux, L Pécheux, Audrey Forest, J Simard, Magalie Celton, Josée Hébert, Etienne Gagnon, Radia M. Johnson, Brian T. Wilhelm, L Gil, Vikie Lamontagne, Sonia Cellot, Anne Bergeron, Angelique Bellemare-Pelletier, Frédéric Barabé, Karine Lagacé
Publikováno v:
Leukemia. 31:1166-1176
Acute myeloid leukemias (AMLs) result from a series of genetic events occurring in a stem or progenitor hematopoietic cell that gives rise to their clonal expansion and an impaired capacity to differentiate. To circumvent the genetic heterogeneity of
Autor:
Magalie Celton, Josée Hébert, Radia M. Johnson, Etienne Gagnon, Sonia Cellot, Audrey Forest, Frédéric Barabé, Anne Bergeron, Brian T. Wilhelm, Laurine Gil, Angelique Bellemare-Pelletier
Publikováno v:
Cancer Research. 75:A2-14
Next generation DNA sequencing has provided significant insights into the genetic determinants of acute myeloid leukemia (AML). Large scale sequencing studies of AML patient cohorts have revealed a remarkable level of genetic heterogeneity between pa
Autor:
Elodie Roques, Magalie Celton, Anne Bergeron, Eva Bresson, Josée Hébert, Sonia Cellot, Frédéric Barabé, Vikie Lamontagne, Brian T. Wilhelm, Karine Lagacé, Thomas Milan
Publikováno v:
Experimental Hematology. 76:S92-S93
Acute myeloid leukemia (AML) is a disease that results from the uncontrolled growth of primitive myeloid progenitor cells that are unable to undergo terminal differentiation. To better understand the genetic and epigenetic changes involved in leukemo
Publikováno v:
Leukemia research. 39(7)
Acute myeloid leukemia (AML) occurs when hematopoietic progenitor cells acquire genetic defects blocking the regulation of normal growth and differentiation. Although recurrent translocations have been identified in AML, almost half of adult AML pati
Autor:
Magalie Celton, Geraldine Gosse, Brian T. Wilhelm, Guy Sauvageau, Audrey Forest, Josée Hébert, Sébastien Lemieux
Publikováno v:
Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2014, 28 (8), pp.1617-1626. ⟨10.1038/leu.2014.67⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2014, 28 (8), pp.1617-1626. ⟨10.1038/leu.2014.67⟩
The GATA2 gene encodes a zinc-finger transcription factor that acts as a master regulator of normal hematopoiesis. Mutations in GATA2 have been implicated in the development of myelodysplastic syndrome and acute myeloid leukemia (AML). Using RNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b651b3467e780bcdbfd5f3c4c482d84b
https://hal.archives-ouvertes.fr/hal-01837733
https://hal.archives-ouvertes.fr/hal-01837733
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2013, 29 (17), pp.2075-2083. ⟨10.1093/bioinformatics/btt352⟩
Bioinformatics, Oxford University Press (OUP), 2013, 29 (17), pp.2075-2083. ⟨10.1093/bioinformatics/btt352⟩
Motivation: The growth of next-generation sequencing (NGS) has not only dramatically accelerated the pace of research in the field of genomics, but it has also opened the door to personalized medicine and diagnostics. The resulting flood of data has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292885debf476c1aa306d517c0f335d9
https://hal.archives-ouvertes.fr/hal-01837681
https://hal.archives-ouvertes.fr/hal-01837681
Publikováno v:
Metabolic Engineering
Metabolic Engineering, Elsevier, 2012, 14 (4), pp.366-379. ⟨10.1016/j.ymben.2012.03.008.⟩
Metabolic Engineering, Elsevier, 2012, 14 (4), pp.366-379. ⟨10.1016/j.ymben.2012.03.008.⟩
International audience; Controlling the amounts of redox cofactors to manipulate metabolic fluxes is emerging as a useful approach to optimizing byproduct yields in yeast biotechnological processes. Redox cofactors are extensively interconnected meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036fab4b8b588ba3401a6730fdc1336d
https://hal.inrae.fr/hal-02645850
https://hal.inrae.fr/hal-02645850
Autor:
Isabelle Sanchez, Vincent Fromion, Sylvie Dequin, Carole Camarasa, Anne Goelzer, Magalie Celton
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2012, 13 (1), pp.317. ⟨10.1186/1471-2164-13-317⟩
BMC Genomics, Vol 13, Iss 1, p 317 (2012)
BMC Genomics 1 (13), 317. (2012)
BMC Genomics, BioMed Central, 2012, 13 (1), pp.317. ⟨10.1186/1471-2164-13-317⟩
BMC Genomics, Vol 13, Iss 1, p 317 (2012)
BMC Genomics 1 (13), 317. (2012)
Background Redox homeostasis is essential to sustain metabolism and growth. We recently reported that yeast cells meet a gradual increase in imposed NADPH demand by progressively increasing flux through the pentose phosphate (PP) and acetate pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ec6147a06cd964d7c071fb11574a83
https://hal.inrae.fr/hal-02649995
https://hal.inrae.fr/hal-02649995