Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Magali Saint-Geniez"'
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract The endothelial glycocalyx, located at the luminal surface of the endothelium, plays an important role in the regulation of leukocyte adhesion, vascular permeability, and vascular homeostasis. Endomucin (EMCN), a component of the endothelial
Externí odkaz:
https://doaj.org/article/f866f4dfaaaf46d7b2fa5d0f1a92f343
Autor:
Margarete M. Karg, May Moorefield, Emma Hoffmann, Hannah Philipose, Drenushe Krasniqi, Cindy Hoppe, Daisy Y. Shu, Shintaro Shirahama, Bruce R. Ksander, Magali Saint-Geniez
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Increased age is a risk factor for the development and progression of retinal diseases including age-related macular degeneration (AMD). Understanding the changes that occur in the eye due to aging is important in enhancing our un
Externí odkaz:
https://doaj.org/article/c95cd76dd86c4d5198c16417aa0be33a
Autor:
Michael Twarog, Joshua Schustak, YongYao Xu, Matthew Coble, Katie Dolan, Robert Esterberg, Qian Huang, Magali Saint-Geniez, Yi Bao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Increasing evidence suggests that chronic inflammation plays an important role in the pathogenesis of age-related macular degeneration (AMD); however, the precise pathogenic stressors and sensors, and their impact on disease progression rema
Externí odkaz:
https://doaj.org/article/c705bd4509e74127925f63bc280d986c
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ef97b5cde9c343d295b5fbf0c2c25d32
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301239 (2024)
The retinal pigment epithelium (RPE) is essential to maintain retinal function, and RPE cell death represents a key pathogenic stage in the progression of several blinding ocular diseases, including age-related macular degeneration (AMD). To identify
Externí odkaz:
https://doaj.org/article/e9f868a54af74dfdac6d332528ec960f
Autor:
Margarete M. Karg, May Moorefield, Emma Hoffmann, Hannah Philipose, Drenushe Krasniqi, Cindy Hoppe, Daisy Y. Shu, Shintaro Shirahama, Bruce R. Ksander, Magali Saint-Geniez
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5ac7dca8046f4015b09628d2d9dcaf67
Autor:
Cindy Park-Windhol, Yin Shan Ng, Jinling Yang, Vincent Primo, Magali Saint-Geniez, Patricia A. D’Amore
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/94659447fca44762934706f78bb20464
Autor:
Daisy Y. Shu, Scott I. Frank, Tessa C. Fitch, Margarete M. Karg, Erik R. Butcher, Emmanuella Nnuji-John, Leo A. Kim, Magali Saint-Geniez
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The retinal pigment epithelium (RPE) acts as a metabolic gatekeeper between photoreceptors and the choroidal vasculature to maintain retinal function. RPE dysfunction is a key feature of age-related macular degeneration (AMD), the leading cause of bl
Externí odkaz:
https://doaj.org/article/3648d0b4c0e048b698aee8e295c6130e
Publikováno v:
Metabolites, Vol 13, Iss 2, p 213 (2023)
Epithelial-mesenchymal transition (EMT) is a dedifferentiation program in which polarized, differentiated epithelial cells lose their cell-cell adhesions and transform into matrix-producing mesenchymal cells. EMT of retinal pigment epithelial (RPE) c
Externí odkaz:
https://doaj.org/article/94a8d54f68b74f5b8c62b9496afaed19
Autor:
Issahy Cano, Zhengping Hu, Dina B. AbuSamra, Magali Saint-Geniez, Yin Shan Eric Ng, Pablo Argüeso, Patricia A. D’Amore
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Galectin-3 (Gal3) is a carbohydrate-binding protein reported to promote angiogenesis by influencing vascular endothelial growth factor-A receptor 2 (VEGFR2) signal transduction. Here we evaluated whether the ability of Gal3 to function as an angiogen
Externí odkaz:
https://doaj.org/article/84a4bf57a94d4616893c2374dcd0a098