Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Magali R. VanLinden"'
Autor:
Øyvind Strømland, Mathias Ziegler, Andrey Nikiforov, Marc Niere, Magali R. VanLinden, Ines Heiland
Publikováno v:
Biochemical Society Transactions. 47:119-130
Research over the last few decades has extended our understanding of nicotinamide adenine dinucleotide (NAD) from a vital redox carrier to an important signalling molecule that is involved in the regulation of a multitude of fundamental cellular proc
Autor:
Mathias Ziegler, Barbara van den Hoeven, Jörn Dietze, Mikhail V. Makarov, Roberto Megias Perez, Roland Sauter, Lars Jansen Sverkeli, Karl Johan Tronstad, Ines Heiland, Marie E. Migaud, Christian Dölle, Lena Elise Høyland, Magali R. VanLinden, Ina Katrine Nitschke Pettersen, Øyvind Strømland, Marc Niere, Camila Cimadamore-Werthein, Ingvill Tolås, Cedric Davidsen, Svein Mjøs
The coenzyme NAD is consumed by signaling enzymes including poly-ADP-ribose-polymerases (PARPs) and sirtuins. Understanding the mechanisms of aging-associated NAD decline and how cells cope with decreased NAD concentrations requires model systems ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff43d9053c8d23e7a6b34e53ee07627c
https://doi.org/10.21203/rs.3.rs-116850/v1
https://doi.org/10.21203/rs.3.rs-116850/v1
Publikováno v:
The Biochemist. 37:9-13
Nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) are two major players in metabolism as they participate as electron carriers in a multitude of redox reactions. Moreover, they act in life and death decisi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1608
Nicotinamide adenine dinucleotide (NAD) is vital to many cellular processes and is distributed between distinct subcellular pools in the compartmentalized eukaryotic cell. The detection and relative quantification of these individual pools is difficu
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969920
Nicotinamide adenine dinucleotide (NAD) is vital to many cellular processes and is distributed between distinct subcellular pools in the compartmentalized eukaryotic cell. The detection and relative quantification of these individual pools is difficu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f50ac6ed0a23df8c3e1d8787dcf87ae
https://doi.org/10.1007/978-1-4939-6993-7_4
https://doi.org/10.1007/978-1-4939-6993-7_4
Publikováno v:
Current Topics in Medicinal Chemistry. 13:2907-2917
NAD plays a major role in all cells as substrate for signal transduction and as cofactor in metabolic redox reactions. Since NAD-dependent signaling involves degradation of the nucleotide, continuous restoration of cellular NAD pools is essential. Mo
Autor:
Karl Johan Tronstad, Ferdinando Palmieri, Gennaro Agrimi, Magali R. VanLinden, Christian Dölle, Marc Niere, Andrey Nikiforov, Veronika Kulikova, Mathias Ziegler, Ina Katrine Nitschke Pettersen, Sissel E. Dyrstad
The mitochondrial NAD pool is particularly important for the maintenance of vital cellular functions. Although at least in some fungi and plants, mitochondrial NAD is imported from the cytosol by carrier proteins, in mammals, the mechanism of how thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb49f799ea9c633d624c38a7a385f848
https://europepmc.org/articles/PMC4646015/
https://europepmc.org/articles/PMC4646015/
Autor:
Mathias Ziegler, Timo Lutter, Johannes Gregor Matthias Rack, Rein Aasland, Magali R. VanLinden
Publikováno v:
Journal of molecular biology. 426(8)
Sirtuin-2 (SIRT2), the cytoplasmic member of the sirtuin family, has been implicated in the deacetylation of nuclear proteins. Although the enzyme has been reported to be located to the nucleus during G2/M phase, its spectrum of targets suggests func