Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Magali De Koninck"'
Autor:
Ana Cuadrado, Daniel Giménez-Llorente, Magali De Koninck, Miguel Ruiz-Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background The cohesin complex organizes the genome-forming dynamic chromatin loops that impact on all DNA-mediated processes. There are two different cohesin complexes in vertebrate somatic cells, carrying the STAG1 or STAG2 subunit, and tw
Externí odkaz:
https://doaj.org/article/cbd5044393304a70b93f6e514254c882
Autor:
Magali De Koninck, Eleonora Lapi, Claudio Badía-Careaga, Itziar Cossío, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Elena Andrada, Andrés Hidalgo, Miguel Manzanares, Francisco X. Real, Ana Losada
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108014- (2020)
Summary: Cohesin mediates sister chromatid cohesion and 3D genome folding. Two versions of the complex carrying STAG1 or STAG2 coexist in somatic vertebrate cells. STAG2 is commonly mutated in cancer, and germline mutations have been identified in co
Externí odkaz:
https://doaj.org/article/4fc2b6de40da498d9e73ce3ab9b6fc0f
Autor:
Miriam Rodríguez-Corsino, Ana Losada, Daniel Giménez-Llorente, Andrés Hidalgo, Francisco X. Real, Claudio Badia-Careaga, Magali De Koninck, Itziar Cossío, Miguel Manzanares, Elena Andrada, Eleonora Lapi
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108014-(2020)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
Universitat Politècnica de Catalunya (UPC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
Universitat Politècnica de Catalunya (UPC)
Cohesin mediates sister chromatid cohesion and 3D genome folding. Two versions of the complex carrying STAG1 or STAG2 coexist in somatic vertebrate cells. STAG2 is commonly mutated in cancer, and germline mutations have been identified in cohesinopat
Autor:
Ana Losada, Daniel Giménez-Llorente, Magali De Koninck, Miriam Rodríguez-Corsino, François Le Dily, Marc A. Marti-Renom, Ana Cuadrado, Aleksandar Kojic, Gonzalo Gómez-López
Publikováno v:
Nature structural & molecular biology
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology
Two variant cohesin complexes containing SMC1, SMC3, RAD21 and either SA1 (also known as STAG1) or SA2 (also known as STAG2) are present in all cell types. We report here their genomic distribution and specific contributions to genome organization in
Autor:
Aleksandar Kojic, Miriam Rodríguez-Corsino, Marc A. Marti-Renom, Ana Losada, Magali De Koninck, Gonzalo Gómez-López, Ana Cuadrado, François Le Dily
In addition to mediating sister chromatid cohesion, cohesin plays a central role in DNA looping and segmentation of the genome into contact domains (TADs). Two variant cohesin complexes that contain either STAG/SA1 or SA2 are present in all cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7c58464d59c4e3f764659596f971dd
Autor:
Magali De Koninck, Ana Losada
Cohesin is a large ring-shaped protein complex, conserved from yeast to human, which participates in most DNA transactions that take place in the nucleus. It mediates sister chromatid cohesion, which is essential for chromosome segregation and homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c0ba02c57b7829bf40cea1ac01063c
https://europepmc.org/articles/PMC5131750/
https://europepmc.org/articles/PMC5131750/