Výsledky vyhledávání - "Magali Cremel"

Innovative approach in Pompe disease therapy: Induction of immune tolerance by antigen-encapsulated red blood cells

Autor: Willy Berlier, Quitterie Barthe, Gaelle Campello, Yann Godfrin, Nathalie Guerin, Françoise Horand, Magali Cremel

Publikováno v: International Journal of Pharmaceutics. 491:69-77

Pompe disease is a glycogen storage disease caused by acid α-glucosidase enzyme deficiency. Currently, the unique treatment is lifelong enzyme replacement therapy ERT with frequent intravenous administration of the recombinant analog alglucosidase-�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc25f8459b43ddbce5924691a0123d38
https://doi.org/10.1016/j.ijpharm.2015.05.062

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In situ targeting of dendritic cells by antigen-loaded red blood cells: A novel approach to cancer immunotherapy

Autor: Yann Godfrin, Alice Banz, Audrey Rembert, Magali Cremel

Publikováno v: Vaccine. 28:2965-2972

Red blood cells (RBCs) were shown to be efficient antigen carriers to target dendritic cells (DCs) and induce cytotoxic T-cell responses. Mouse RBCs were loaded with ovalbumin (RBC-OVA) and injected with Poly (I:C) into mice. Phagocytosis of RBC-OVA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bef66b021f2a7815d7c39159eae8af4
https://doi.org/10.1016/j.vaccine.2010.02.013

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Female genital tract immunization: Evaluation of candidate immunoadjuvants on epithelial cell secretion of CCL20 and dendritic/Langerhans cell maturation

Autor: Christian Genin, Olivier Delézay, Hind Hamzeh-Cognasse, Magali Cremel

Publikováno v: Vaccine. 24:5744-5754

The female genital tract is an important site for numerous pathogens entry. Local immunization, generating specific mucosal IgA and systemic IgG, represents an interesting alternative immunization pathway. However, such a vaccine strategy needs mucos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f84f511152fc491c2059b6e2320ec93
https://doi.org/10.1016/j.vaccine.2006.04.044

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Can red blood cells prove to be a useful tool in tumor immunotherapy?

Autor: Françoise Horand, Yann Godfrin, Magali Cremel

Publikováno v: Immunotherapy. 4:871-873

of migrating to the secondary lymphoid organs and of inducing an effective cytotoxic T‐cell response. In the second strategy, a variety of approaches have been explored to load and mature DCs directly in vivo such as generating TAAs linked to an an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1843dc4ded49bc89e6a57c16c7afce8
https://doi.org/10.2217/imt.12.88

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Abstract 2356: Erythrocytes used as tumor antigen delivery system to target antigen-presenting cells embody an innovative approach for in situ cancer immunotherapy

Autor: Willy Berlier, Yann Godfrin, Françoise Horand, Nathalie Guerin, Magali Cremel, Vanessa Bourgeaux, Quitterie Barthe

Publikováno v: Cancer Research. 76:2356-2356

Introduction: In current vaccine therapy, efficient delivery of tumor antigens (TA) to antigen-presenting cells (APC) represents a major step toward the development of strong TA-specific immune response including cytotoxic T lymphocyte (CTL) inductio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e5a18a94bd2c9efd23c2713db9dae72
https://doi.org/10.1158/1538-7445.am2016-2356

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Red blood cells as innovative antigen carrier to induce specific immune tolerance

Autor: Nathalie Guerin, Françoise Horand, Alice Banz, Magali Cremel, Yann Godfrin

Publikováno v: International journal of pharmaceutics. 443(1-2)

The route of administration, the dose of antigen as well as the type of antigen-presenting cells (APCs) targeted are important factors to induce immune tolerance. Despite encouraging results obtained in animal models, intravenous injection of soluble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e8f93635196a46d31c8352797bd16
https://pubmed.ncbi.nlm.nih.gov/23305866

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Sublingual immunization with an HIV subunit vaccine induces antibodies and cytotoxic T cells in the mouse female genital tract

Autor: Fabienne Anjuère, Carmelo Luci, Concepción Marañón, Nicolas Çuburu, Catherine Hervouet, Anne Hosmalin, Cecil Czerkinsky, Lene Vimeux, Selma Bekri, Magali Cremel

Publikováno v: Vaccine
Vaccine, 2010, 28 (34), pp.5582-90. ⟨10.1016/j.vaccine.2010.06.033⟩
Vaccine, Elsevier, 2010, 28 (34), pp.5582-90. ⟨10.1016/j.vaccine.2010.06.033⟩
Vaccine, Elsevier, 2010, 28 (34), pp.5582-90. 〈10.1016/j.vaccine.2010.06.033〉

International audience; A vaccine against heterosexual transmission by human immunodeficiency virus (HIV) should generate cytotoxic and antibody responses in the female genital tract and in extra-genital organs. We report that sublingual immunization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8a10ea887159b0ebf1b2eb2c246b88
https://hal.science/hal-00545804

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Characterization of CCL20 secretion by human epithelial vaginal cells: involvement in Langerhans cell precursor attraction

Autor: Magali Cremel, Jean-Claude Bernengo, Hind Hamzeh, Willy Berlier, Philip Lawrence, Olivier Delézay, Marie-Caroline Dieu-Nosjean, Fabrice Cognasse, Christian Genin, Claude Lambert

Publikováno v: Journal of leukocyte biology. 78(1)

Mucosa represents the main site of pathogen/cell interactions. The two main types of cells forming the epithelial structure [epithelial cells and Langerhans cells (LC)] coordinate the first defense responses to avoid infection. To evaluate the involv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8af19409493aadd9a4ba6b224d2f4b
https://pubmed.ncbi.nlm.nih.gov/15831560

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