Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Magali Champion"'
Autor:
Mathilde Pacault, Camille Verebi, Magali Champion, Lucie Orhant, Alexandre Perrier, Emmanuelle Girodon, France Leturcq, Dominique Vidaud, Claude Férec, Thierry Bienvenu, Romain Daveau, Juliette Nectoux
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280976 (2023)
Non-invasive prenatal diagnosis of single-gene disorders (SGD-NIPD) has been widely accepted, but is mostly limited to the exclusion of either paternal or de novo mutations. Indeed, it is still difficult to infer the inheritance of the maternal allel
Externí odkaz:
https://doaj.org/article/924e81eb10694715866e532df5d26618
Autor:
Magali Champion, Kevin Brennan, Tom Croonenborghs, Andrew J. Gentles, Nathalie Pochet, Olivier Gevaert
Publikováno v:
EBioMedicine, Vol 27, Iss C, Pp 156-166 (2018)
The availability of increasing volumes of multi-omics profiles across many cancers promises to improve our understanding of the regulatory mechanisms underlying cancer. The main challenge is to integrate these multiple levels of omics profiles and es
Externí odkaz:
https://doaj.org/article/e7ca88bede014fee8a3481f7d2f5569d
Autor:
Rajat Rohatgi, Jan E. Carette, Branimir I. Sikic, Olivier Gevaert, Magali Champion, Caleb Marceau, Zahra Bahrami-Nejad, Andres M. Lebensohn, Ramin Dubey
Overview of the screening strategy in haploid cells (S1); Correlation between ABCB1 and SMARCB1 mRNA expression levels across multiple human cancers represented in the TCGA database (S2); Correlation between SMARCB1 expression and doxorubicin resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b784cc4eb7a39463b4cdd52319299ce0
https://doi.org/10.1158/0008-5472.22412193
https://doi.org/10.1158/0008-5472.22412193
Autor:
Rajat Rohatgi, Jan E. Carette, Branimir I. Sikic, Olivier Gevaert, Magali Champion, Caleb Marceau, Zahra Bahrami-Nejad, Andres M. Lebensohn, Ramin Dubey
Anthracyclines are among the most effective yet most toxic drugs used in the oncology clinic. The nucleosome-remodeling SWI/SNF complex, a potent tumor suppressor, is thought to promote sensitivity to anthracyclines by recruiting topoisomerase IIa (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e18818ab1e7c5118b38b7bfdb79eaf4
https://doi.org/10.1158/0008-5472.c.6508380.v1
https://doi.org/10.1158/0008-5472.c.6508380.v1
Autor:
Rajat Rohatgi, Jan E. Carette, Branimir I. Sikic, Olivier Gevaert, Magali Champion, Caleb Marceau, Zahra Bahrami-Nejad, Andres M. Lebensohn, Ramin Dubey
Top 35 hits from the doxorubicin screen based on a False Discovery Rate corrected p-value threshold of 0.01.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941a54cc9f74bb82eed23039b2516f32
https://doi.org/10.1158/0008-5472.22412184
https://doi.org/10.1158/0008-5472.22412184
Autor:
Rajat Rohatgi, Jan E. Carette, Branimir I. Sikic, Olivier Gevaert, Magali Champion, Caleb Marceau, Zahra Bahrami-Nejad, Andres M. Lebensohn, Ramin Dubey
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308c33a69f36bc173b013d4ea086a688
https://doi.org/10.1158/0008-5472.22412187
https://doi.org/10.1158/0008-5472.22412187
Autor:
Pierre Neuvial, Mohamed Elati, Etienne Birmelé, Julien Chiquet, Magali Champion, François Radvanyi
Publikováno v:
Journal of bioinformatics and computational biology. 19(1)
In many cancers, mechanisms of gene regulation can be severely altered. Identification of deregulated genes, which do not follow the regulation processes that exist between transcription factors and their target genes, is of importance to better unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4611772066c51d99fdd54b4f89ff8d2b
https://pubmed.ncbi.nlm.nih.gov/33653235
https://pubmed.ncbi.nlm.nih.gov/33653235
Publikováno v:
Statistics and Computing. 28:905-921
We address the issue of recovering the structure of large sparse directed acyclic graphs from noisy observations of the system. We propose a novel procedure based on a specific formulation of the $$\ell _1$$ -norm regularized maximum likelihood, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05fb1e90198a5ec8930cebe5bf200bee
https://doi.org/10.1007/s11222-017-9769-z
https://doi.org/10.1007/s11222-017-9769-z
Publikováno v:
Journal of Statistical Planning and Inference. 155:19-41
This paper focuses on the analysis of L2L2-Boosting algorithms for linear regressions. Consistency results were obtained for high-dimensional models when the number of predictors grows exponentially with the sample size nn. We propose a new result fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a65309c0a42142d4f4579f7f6b1913
https://doi.org/10.1016/j.jspi.2014.07.006
https://doi.org/10.1016/j.jspi.2014.07.006
Autor:
Andres M. Lebensohn, Olivier Gevaert, Magali Champion, Jan E. Carette, Zahra Bahrami-Nejad, Rajat Rohatgi, Caleb D. Marceau, Branimir I. Sikic, Ramin Dubey
Publikováno v:
Cancer research. 76(19)
Anthracyclines are among the most effective yet most toxic drugs used in the oncology clinic. The nucleosome-remodeling SWI/SNF complex, a potent tumor suppressor, is thought to promote sensitivity to anthracyclines by recruiting topoisomerase IIa (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d3050dfd115a6762e2aae65b6113ac
https://pubmed.ncbi.nlm.nih.gov/27503929
https://pubmed.ncbi.nlm.nih.gov/27503929