Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Magali Breckler"'
Autor:
Johanna Sigaux, Christophe Junot, Marie-Christophe Boissier, Mylène Petit, Magali Breckler, Florence Castelli, François Fenaille, Paul-Henri Roméo, Luca Semerano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Using a new red blood cell (RBC) metabolite extraction protocol, we performed a metabolomic analysis on RBCs in rheumatoid arthritis (RA) patients treated or not with methotrexate (MTX), with the two following objectives: to compare the RBC
Externí odkaz:
https://doaj.org/article/70f13b2d3953432ba82a48b514092aa6
Autor:
Majda Lyna Mebrek, Tessnime Abaab, Delphine Lemeiter, Magali Breckler, Roxane Hervé, Mylène Petit, Gaëlle Clavel, Johanna Sigaux, Marie-Christophe Boissier, Luca Semerano, Jérôme Biton, Natacha Bessis
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and objectivesAxial spondyloarthritis (axSpA) is a chronic inflammatory disease involving the spine, peripheral joints, and entheses. Functional impairment of regulatory T cells (Treg) is linked to inflammatory diseases, but limited data i
Externí odkaz:
https://doaj.org/article/f0eeb61240364a7da9d12c6de065592a
Autor:
Baptiste Hervier, Matthieu Ribon, Nadine Tarantino, Julie Mussard, Magali Breckler, Vincent Vieillard, Zahir Amoura, Alexander Steinle, Reinhild Klein, Ina Kötter, Patrice Decker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is a severe autoimmune disease of unknown etiology. The major histocompatibility complex (MHC) class I-related chain A (MICA) and B (MICB) are stress-inducible cell surface molecules. MICA and MICB label malfunction
Externí odkaz:
https://doaj.org/article/41ec9e83eb674cb8be52e3461cdbcea1
Autor:
Jasmin Felux, Annika Erbacher, Magali Breckler, Roxane Hervé, Delphine Lemeiter, Hans Georg Mannherz, Markus Napirei, Hans-Georg Rammensee, Patrice Decker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Increased concentrations of circulating chromatin, especially oligo-nucleosomes, are observed in sepsis, cancer and some inflammatory autoimmune diseases like systemic lupus erythematosus (SLE). In SLE, circulating nucleosomes mainly result from incr
Externí odkaz:
https://doaj.org/article/52da05a20e3049fe837f567d8813ae04
Autor:
M. Petit, Luca Semerano, Johanna Sigaux, F. Fenaille, C. Junot, P.H. Roméo, F. Castelli, MC Boissier, Magali Breckler
Publikováno v:
Revue du Rhumatisme. 87:A26-A27
Introduction L’analyse metabolomique reflete l’etat d’un systeme biologique et peut discriminer entre sujets sains et malades et predire la reponse aux traitements. Dans les etudes de metabolomique faites dans la polyarthrite rhumatoide (PR), l
Autor:
Natacha Bessis, Luca Semerano, Marianne Ziol, Jérôme Biton, Jörg Tost, Magali Breckler, Roxane Hervé, Marie-Christophe Boissier, Maxime Batignes, Florence Busato, Patrice Decker, Delphine Lemeiter, Gaëlle Clavel, Majda Lyna Mebrek, François Santinon
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)References. 72(4)
OBJECTIVE To study the involvement of Treg cells expressing tumor necrosis factor receptor type II (TNFRII) in exerting control of inflammation in experimental models and in the response to anti-TNF treatments in patients with rheumatoid arthritis (R
Autor:
Claire, Deback, Antoine, Rousseau, Magali, Breckler, Lucie, Molet, David, Boutolleau, Sonia, Burrel, Anne-Marie, Roque-Afonso, Marc, Labetoulle
Publikováno v:
Antiviral therapy. 23(8)
CacicolCacicolThe vehicle had no effect, dose-dependent effects were demonstrated when HSV-1 SC16, HSV-1 PSLR, VZV ATH and VZV FLO were inoculated in the presence of CacicolCacicol
Publikováno v:
Current Heart Failure Reports
Current Heart Failure Reports, Current Medicine Group, 2011, 8 (3), pp.159-67. ⟨10.1007/s11897-011-0062-8⟩
Current Heart Failure Reports, 2011, 8 (3), pp.159-67. ⟨10.1007/s11897-011-0062-8⟩
Current Heart Failure Reports, Current Medicine Group, 2011, 8 (3), pp.159-67. ⟨10.1007/s11897-011-0062-8⟩
Current Heart Failure Reports, 2011, 8 (3), pp.159-67. ⟨10.1007/s11897-011-0062-8⟩
International audience; Cyclic adenosine 3',5'-monophosphate (cAMP) mediates the biological effects of various hormones and neurotransmitters. Stimulation of cardiac β-adrenergic receptors (β-AR) via catecholamines leads to activation of adenylyl c
Autor:
Eric Morel, Bertrand Crozatier, Anne-Coline Laurent, Isabelle Hmitou, Mélanie Métrich, Nicolas Duquesnes, Magali Breckler, Delphine Courillau, Jean-Paul Blondeau, Frank Lezoualc'h
Publikováno v:
Cellular Signalling. 22:1459-1468
Epac (Exchange protein directly activated by cAMP) is a sensor for cAMP and represents a novel mechanism for governing cAMP signalling. Epac is a guanine nucleotide exchange factor (GEF) for the Ras family of small GTPases, Rap. Previous studies demo
Autor:
Claudine Deloménie, Anne-Coline Laurent, Maxime Branchereau, Frank Lezoualc'h, Olivier Cazorla, Loubina Fazal, Alexandre Lucas, Pauline Soulas-Sprauel, Florence Tortosa, Magali Breckler, Pauline Marck, Christophe Heymes, Eric Morel, Magali Berthouze-Duquesnes, Bertrand Crozatier, Audrey Varin, Jean-Nicolas Schickel, Malik Bisserier, Annélie de Régibus
Publikováno v:
Circulation. 131(4)
Background— Cardiac hypertrophy is an early hallmark during the clinical course of heart failure and is regulated by various signaling pathways. However, the molecular mechanisms that negatively regulate these signal transduction pathways remain po