Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Mafalda Lopes"'
Publikováno v:
Geotecnia, Iss 160 (2024)
As formações argilosas do Miocénico de Lisboa foram alvo de um estudo extensivo de caracterização, com vista a estabelecer um conjunto de intervalos de valores para os principais índices físicos, parâmetros de compressibilidade e de resistên
Externí odkaz:
https://doaj.org/article/ae226b003b4f489e96b8487f6faccd45
Autor:
Rita Rosado-Ramos, Gonçalo M. Poças, Daniela Marques, Alexandre Foito, David M. Sevillano, Mafalda Lopes-da-Silva, Luís G. Gonçalves, Regina Menezes, Marcel Ottens, Derek Stewart, Alain Ibáñez de Opakua, Markus Zweckstetter, Miguel C. Seabra, César S. Mendes, Tiago Fleming Outeiro, Pedro M. Domingos, Cláudia N. Santos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
In this work, the authors identify Genipin as a small iridoid able to prevent alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.
Externí odkaz:
https://doaj.org/article/6e0052eb0e2b432c9b02cba0d241c7e9
Autor:
Karen M. Page, Jessica J. McCormack, Mafalda Lopes-da-Silva, Francesca Patella, Kimberly Harrison-Lavoie, Jemima J. Burden, Ying-Yi Bernadette Quah, Dominic Scaglioni, Francesco Ferraro, Daniel F. Cutler
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background In vertebrate cells, the Golgi functional subunits, mini-stacks, are linked into a tri-dimensional network. How this “ribbon” architecture relates to Golgi functions remains unclear. Are all connections between mini-stacks equ
Externí odkaz:
https://doaj.org/article/ea370c24b3234d728be9cf0d1e4f597f
Publikováno v:
SN Applied Sciences, Vol 4, Iss 1, Pp 1-14 (2021)
Abstract Undrained shear strength plays a fundamental role on the behaviour of clays. In overconsolidated clays, this parameter is largely influenced by test conditions, namely consolidation stress. “Prazeres Clay” is a Miocene overconsolidated f
Externí odkaz:
https://doaj.org/article/0ec63ca780f443108ec1b0c4a28efa00
Autor:
Ana F. Raimundo, Sofia Ferreira, Vânia Pobre, Mafalda Lopes-da-Silva, José A. Brito, Daniel J. V. A. dos Santos, Nuno Saraiva, Cláudia N. dos Santos, Regina Menezes
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionDiabetes is one of the major metabolic diseases worldwide. Despite being a complex systemic pathology, the aggregation and deposition of Islet Amyloid Polypeptide (IAPP), or amylin, is a recognized histopathological marker of the disease.
Externí odkaz:
https://doaj.org/article/a547e5291eb2421b9237abf1524f1d42
Autor:
Eva Alegre-Cortés, Alberto Giménez-Bejarano, Elisabet Uribe-Carretero, Marta Paredes-Barquero, André R. A. Marques, Mafalda Lopes-da-Silva, Otília V. Vieira, Saray Canales-Cortés, Pedro J. Camello, Guadalupe Martínez-Chacón, Ana Aiastui, Roberto Fernández-Torrón, Adolfo López de Munain, Patricia Gomez-Suaga, Mireia Niso-Santano, Rosa A. González-Polo, José M. Fuentes, Sokhna M. S. Yakhine-Diop
Publikováno v:
Cells, Vol 11, Iss 19, p 3018 (2022)
Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase gene. AKT dephosphorylation and autophagy are associated with DM1. Autophagy
Externí odkaz:
https://doaj.org/article/63ec18c48d0044c082b29aaa2f385fd7
Autor:
Silène T Wavre-Shapton, Tanya Tolmachova, Mafalda Lopes da Silva, Clare E Futter, Miguel C Seabra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57769 (2013)
The retinal pigment epithelium (RPE) is a pigmented monolayer of cells lying between the photoreceptors and a layer of fenestrated capillaries, the choriocapillaris. Choroideremia (CHM) is an X-linked progressive degeneration of these three layers ca
Externí odkaz:
https://doaj.org/article/453b2dad9d074a18b7e21757768e4d1a
Autor:
Silène T. Wavre-Shapton, Tanya Tolmachova, Mafalda Lopes da Silva, Clare E. Futter, Miguel C. Seabra
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/afcb7496b1ad49e6b2f83bc9beec83cc
Autor:
Fonseca, Ana Fragoso, Coelho, Rita, da-Silva, Mafalda Lopes-, Lemos, Luísa, Hall, Michael J., Oliveira, Daniela, Falcão, Ana Sofia, Tenreiro, Sandra, Seabra, Miguel C., Antas, Pedro
Publikováno v:
Stem Cells & Development; Oct2024, Vol. 33 Issue 19/20, p528-539, 12p