Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mafalda Bessa-Gonçalves"'
Autor:
Ana J. Silva, Joana R. Ferreira, Carla Cunha, João V. Corte-Real, Mafalda Bessa-Gonçalves, Mario A. Barbosa, Susana G. Santos, Raquel M. Gonçalves
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Low back pain is a highly prevalent clinical problem and intervertebral disc (IVD) degeneration is now accepted as the major pathophysiological mechanism responsible for this condition. Accumulating evidence suggests that inflammation plays a crucial
Externí odkaz:
https://doaj.org/article/57849c3c0f164ecdb9461aaa488d9d1f
Autor:
José H. Teixeira, Andreia M. Silva, Maria Inês Almeida, Mafalda Bessa-Gonçalves, Carla Cunha, Mário A. Barbosa, Susana G. Santos
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5436 (2019)
Rheumatoid arthritis (RA) is a systemic disease that affects the osteoarticular system, associated with bone fragility and increased risk of fractures. Herein, we aimed to characterize the systemic impact of the rat collagen-induced arthritis (CIA) m
Externí odkaz:
https://doaj.org/article/066b6f97504a4005b649741cc60fbd09
Autor:
Marco Araújo, Cristina C. Barrias, Susana G. Santos, Mafalda Bessa-Gonçalves, Aureliana Sousa, João Silveira
Publikováno v:
Biomaterials Science. 9:6510-6527
Healing of intestinal chronic wounds remains a major challenge as current therapies are ineffective in promoting proper regeneration of the damaged intestinal wall. An innovative concept, based on a bioinspired multifunctional alginate-melanin hybrid
Autor:
Susana G. Santos, Bérengère J.C. Luthringer-Feyerabend, Mário A. Barbosa, Heike Helmholz, Mafalda Bessa-Gonçalves, Regine Willumeit-Römer, Joao Paulo Bras, Andreia M. Silva
Publikováno v:
Bessa-Gonçalves, M.; Silva, A.; Brás, J.; Helmholz, H.; Luthringer-Feyerabend, B.; Willumeit-Römer, R.; Barbosa, M.; Santos, S.: Fibrinogen and magnesium combination biomaterials modulate macrophage phenotype, NF-kB signaling and crosstalk with mesenchymal stem/stromal cells. In: Acta Biomaterialia. Vol. 114 (2020) 471-484. (DOI: /10.1016/j.actbio.2020.07.028)
Macrophage behavior upon biomaterial implantation conditions the inflammatory response and subsequent tissue repair. The hypothesis behind this work was that fibrinogen (Fg) and magnesium (Mg) biomaterials, used in combination (FgMg) could act synerg
Autor:
Mário A. Barbosa, Ana Rita Almeida, Daniel M. Vasconcelos, Mafalda Bessa-Gonçalves, Susana G. Santos
Publikováno v:
Journal of Biomedical Materials Research Part A. 108:851-862
Fibrinogen (Fg) is a pro-inflammatory protein with pro-healing properties. Previous work showed that fibrinogen 3D scaffolds (Fg-3D) promote bone regeneration, but the cellular players were not identified. Osteoclasts are bone resorbing cells that pr
Autor:
Susana G. Santos, Andreia M. Silva, Carla Cunha, Mário A. Barbosa, José H. Teixeira, Mafalda Bessa-Gonçalves, Maria Inês Almeida
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 21
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5436 (2019)
Volume 20
Issue 21
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5436 (2019)
Rheumatoid arthritis (RA) is a systemic disease that affects the osteoarticular system, associated with bone fragility and increased risk of fractures. Herein, we aimed to characterize the systemic impact of the rat collagen-induced arthritis (CIA) m
Autor:
A.P. Fontes‐Sousa, Eduardo Martins-Dias, Mafalda Bessa-Gonçalves, Paulo Correia-de-Sá, Bruno Bragança
Publikováno v:
Drug Discovery Today. 23:1285-1292
Pulmonary arterial hypertension (PAH) is a maladaptive disorder characterized by increased pulmonary vascular resistance leading to right ventricular failure and death. Adenosine released by injured tissues, such as the lung and heart, influences tis
Autor:
Mafalda, Bessa-Gonçalves, Bruno, Bragança, Eduardo, Martins-Dias, Paulo, Correia-de-Sá, Ana Patrícia, Fontes-Sousa
Publikováno v:
Drug discovery today. 23(6)
Pulmonary arterial hypertension (PAH) is a maladaptive disorder characterized by increased pulmonary vascular resistance leading to right ventricular failure and death. Adenosine released by injured tissues, such as the lung and heart, influences tis