Recombinant mycobacterial DNA-binding protein 1 with post-translational modifications boosts IFN-gamma production from BCG-vaccinated individuals' blood cells in combination with CpG-DNA.

Autor: Ozeki Y; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan. yuriozeki@med.niigata-u.ac.jp., Yokoyama A; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan.; Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8654, Japan., Nishiyama A; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Yoshida Y; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Ohara Y; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Mashima T; Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan., Tomiyama C; Graduate School of Health Sciences, Niigata University, 2-746, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8518, Japan., Shaban AK; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Takeishi A; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Osada-Oka M; Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, 1-5, Shimogamo-Nakaragi-Cho, Sakyo-Ku, Kyoto, 606-8522, Japan., Yamaguchi T; Department of Bacteriology 1, National Institute of Infectious Disease, 1-23-1, Sinjuku-Ku, Tokyo, 162-8640, Japan., Tateishi Y; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Maeyama JI; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan.; Reseach Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, 4-7-1, Musashimurayama, Tokyo, 208-0011, Japan., Hakamata M; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan.; Department of Respiratory Medicine and Infectious Disease, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Moro H; Department of Respiratory Medicine and Infectious Disease, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Kikuchi T; Department of Respiratory Medicine and Infectious Disease, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan., Hayashi D; Central Laboratory, Japan BCG Laboratory, 3-1-5 Matsuyama, Kiyose, Tokyo, 204-0022, Japan., Suzuki F; Faculty of Medical Sciences, University of Fukui, 23-3, Matsuokashimoaizuki, Eiheiji-Cho, Yoshida-Gun, Fukui, 910-1193, Japan., Yamamoto T; Central Laboratory, Japan BCG Laboratory, 3-1-5 Matsuyama, Kiyose, Tokyo, 204-0022, Japan.; Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, 4-2-1 Aobacho, Higashi-Murayama, Tokyo, 189-0002, Japan., Iho S; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan.; Faculty of Medical Sciences, University of Fukui, 23-3, Matsuokashimoaizuki, Eiheiji-Cho, Yoshida-Gun, Fukui, 910-1193, Japan.; Louis Pasteur Center for Medical Research, 103-5 Tanaka Monzen-cho, Sakyo-ku, Kyoto, 606-8225, Japan., Katahira M; Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan., Yamamoto S; Central Laboratory, Japan BCG Laboratory, 3-1-5 Matsuyama, Kiyose, Tokyo, 204-0022, Japan.; Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, 4-2-1 Aobacho, Higashi-Murayama, Tokyo, 189-0002, Japan., Matsumoto S; Department of Bacteriology, Niigata University School of Medicine, 1-757, Asahimachi-Dori, Chuo-Ku, Niigata, 951-8510, Japan. sohkichi@med.niigata-u.ac.jp.; Laboratory of Tuberculosis, Institute of Tropical Disease, Universitas Airlangga, Kampus C JI. Mulyorejo, Surabaya, 60113, Indonesia. sohkichi@med.niigata-u.ac.jp.; Division of Research Aids, Hokkaido University Institute for Vaccine Research and Development, Kita 20, Nishi 10, Kita-Ku, Sapporo, 001-0020, Japan. sohkichi@med.niigata-u.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2024 Apr 21; Vol. 14 (1), pp. 9141. Date of Electronic Publication: 2024 Apr 21.

Streptococcus pyogenes TrxSR Two-Component System Regulates Biofilm Production in Acidic Environments.

Autor: Isaka M; Department of Bacteriology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan., Okamoto A; Department of School Health Sciences, Aichi University of Education, Kariya, Japan., Miura Y; Faculty of Wellness, Department of Nutrition, Shigakkan University, Ohbu, Japan., Tatsuno I; Department of Bacteriology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan., Maeyama JI; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan., Hasegawa T; Department of Bacteriology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.

Publikováno v: Infection and immunity [Infect Immun] 2021 Oct 15; Vol. 89 (11), pp. e0036021. Date of Electronic Publication: 2021 Aug 23.

Comparative Study of the Susceptibility to Oxidative Stress between Two Types of Mycobacterium bovis BCG Tokyo 172.

Autor: Taniguchi K; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Hayashi D; Japan BCG Laboratory, Kiyose, Tokyo, Japan., Yasuda N; Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan., Nakayama M; Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan., Yazawa K; Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan., Ogawa S; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Miyatake Y; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Suda S; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Tomita H; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Tokuda M; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Itoh S; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Maeyama JI; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan., Ohara N; Department of Oral Microbiology, Graduated School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Yamamoto S; Japan BCG Laboratory, Kiyose, Tokyo, Japan., Hida S; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Onozaki K; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan., Takii T; Department of Molecular Health Sciences, Graduated School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan t-takii@jata.or.jp.; Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Tokyo, Japan.

Publikováno v: MSphere [mSphere] 2021 Mar 10; Vol. 6 (2). Date of Electronic Publication: 2021 Mar 10.

CpG ODN G9.1 as a novel nasal ODN adjuvant elicits complete protection from influenza virus infection without causing inflammatory immune responses.

Autor: Tateishi K; Influenza Virus Research Center, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashi-murayama-shi, Tokyo 208-0011, Japan; Japan Agency for Medical Research and Development, 1-7-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan., Fujihashi K; Division of Clinical Vaccinology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo 108-8639, Japan; Department of Pediatric Dentistry, The Institute of Oral Health Research, The University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA., Yamamoto N; Influenza Virus Research Center, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashi-murayama-shi, Tokyo 208-0011, Japan; Department of Infection Control Science, Juntendo University, Tokyo, Japan., Hasegawa H; Department of Pathology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan., Ainai A; Department of Pathology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan., Sato K; Influenza Virus Research Center, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashi-murayama-shi, Tokyo 208-0011, Japan., Iho S; Division of Medicine, Faculty of Medical Sciences, University of Fukui, Yoshida-gun, Fukui and Department of Bacteriology, Niigata University Graduate School of Medicine, Niigata-shi, Niigata, Japan., Yamamoto S; Central Laboratory, Japan BCG Laboratory, Kiyose-shi, Tokyo, Japan., Maeyama JI; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Musashi-murayama-shi, Tokyo, Japan., Odagiri T; Influenza Virus Research Center, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashi-murayama-shi, Tokyo 208-0011, Japan., Asanuma H; Influenza Virus Research Center, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashi-murayama-shi, Tokyo 208-0011, Japan; Department of Pathology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan. Electronic address: asa@nih.go.jp.

Publikováno v: Vaccine [Vaccine] 2019 Aug 23; Vol. 37 (36), pp. 5382-5389. Date of Electronic Publication: 2019 Jul 22.