Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maeve Long"'
Autor:
Sara Feola, Manlio Fusciello, Beatriz Martins, Erkko Ylösmäki, Vincenzo Cerullo, Firas Hamdan, Jacopo Chiaro, Yvonne Giannoula, Maeve Long, Michaela Feodoroff, Gabriella Antignani, Salvatore Russo, Otto Kari, Petrus Järvinen, Harry Nisen, Anna Kreutzman, Satu Mustjoki, Thomas G McWilliams, Mikaela Grönholm, Moon Hee Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background Despite the success of immune checkpoint inhibitors against PD-L1 in the clinic, only a fraction of patients benefit from such therapy. A theoretical strategy to increase efficacy would be to arm such antibodies with Fc-mediated effector m
Externí odkaz:
https://doaj.org/article/75228aef30a64c3b90f489f356c51753
Publikováno v:
Cells, Vol 9, Iss 5, p 1089 (2020)
In the endomembrane system of mammalian cells, membrane traffic processes require a high degree of regulation in order to ensure their specificity. The range of molecules that participate in trafficking events is truly vast, and much attention to dat
Externí odkaz:
https://doaj.org/article/468e1a41267344da988f96deb27ef79a
Autor:
Alanna C. Green, Petra Marttila, Nicole Kiweler, Christina Chalkiadaki, Elisée Wiita, Victoria Cookson, Antoine Lesur, Kim Eiden, François Bernardin, Karl S. A. Vallin, Sanjay Borhade, Maeve Long, Elahe Kamali Ghahe, Julio J. Jiménez-Alonso, Ann-Sofie Jemth, Olga Loseva, Oliver Mortusewicz, Marianne Meyers, Elodie Viry, Annika I. Johansson, Ondřej Hodek, Evert Homan, Nadilly Bonagas, Louise Ramos, Lars Sandberg, Morten Frödin, Etienne Moussay, Ana Slipicevic, Elisabeth Letellier, Jérôme Paggetti, Claus Storgaard Sørensen, Thomas Helleday, Martin Henriksson, Johannes Meiser
Cancer cells fuel their increased need for nucleotide supply by upregulating one-carbon (1C) metabolism, including the enzymes methylenetetrahydrofolate dehydrogenase-cyclohydrolase 1 and 2 (MTHFD1 and MTHFD2). TH9619 is a potent inhibitor of dehydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef4c9b031ee478e94f3df8742d2401f
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206656
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206656
Autor:
Maeve Long, Thomas G. McWilliams
Publikováno v:
Seminars in Cancer Biology. 66:12-21
Autophagy refers to an essential mechanism that evolved to sustain eukaryotic homeostasis and metabolism during instances of nutrient deprivation. During autophagy, intracellular cargo is encapsulated and delivered to the lysosome for elimination. Lo
Autor:
Maeve Long, Thomas G. McWilliams
Publikováno v:
Autophagy. 19:724-725
Mitophagy neutralizes defective mitochondria
Publikováno v:
Journal for ImmunoTherapy of Cancer
Autor:
Petrus Järvinen, Manlio Fusciello, Sara Feola, Jacopo Chiaro, Otto K. Kari, Harry Nisen, Firas Hamdan, Mikaela Grönholm, Erkko Ylösmäki, Yvonne Giannoula, Anna Kreutzman, Moon Hee Lee, Thomas G. McWilliams, Satu Mustjoki, Gabriella Antignani, Beatriz Martins, Michaela Feodoroff, Vincenzo Cerullo, Maeve Long
Publikováno v:
Cancer Research. 81:1867-1867
Despite the success of immune checkpoint inhibitors in the clinic, they only benefit a fraction of patients. A theoretical strategy to increase efficacy would be to enhance such antibodies with Fc-mediated effector mechanisms. Current IgG1 antibodies
Autor:
Jeremy C. Simpson, Maeve Long
Publikováno v:
Tissue and Cell. 49:163-169
The Golgi complex is the central unit of the secretory pathway, modifying, processing and sorting proteins and lipids to their correct cellular localisation. Changes to proteins at the Golgi complex can have deleterious effects on the function of thi
Publikováno v:
Cells, Vol 9, Iss 1089, p 1089 (2020)
Cells
Volume 9
Issue 5
Cells
Volume 9
Issue 5
In the endomembrane system of mammalian cells, membrane traffic processes require a high degree of regulation in order to ensure their specificity. The range of molecules that participate in trafficking events is truly vast, and much attention to dat