Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine

Autor: Shuang-Qi Tang, Frédéric Bihel, Delphine Garnier, Martine Schmitt, Jacques Bricard, Séverine Schneider, Maeva Leloire, Julie Mohr, Patrick Gizzi

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, In press, ⟨10.1021/acs.joc.0c01764⟩
Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.0c01764⟩

International audience; Herein, we report the diastereoselective synthesis of a 3-amino-1,2,4-oxadiazine (AOXD) scaffold. The presence of a N–O bond in the ring prevents the planar geometry of the aromatic system and induces a strong decrease in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b72e269e2f2c2b67b432e748bbfa018
https://doi.org/10.1021/acs.joc.0c01764