Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maeva Dutilleul"'
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Caroline Le Guiner, Laurent Servais, Marie Montus, Thibaut Larcher, Bodvaël Fraysse, Sophie Moullec, Marine Allais, Virginie François, Maeva Dutilleul, Alberto Malerba, Taeyoung Koo, Jean-Laurent Thibaut, Béatrice Matot, Marie Devaux, Johanne Le Duff, Jack-Yves Deschamps, Inès Barthelemy, Stéphane Blot, Isabelle Testault, Karim Wahbi, Stéphane Ederhy, Samia Martin, Philippe Veron, Christophe Georger, Takis Athanasopoulos, Carole Masurier, Federico Mingozzi, Pierre Carlier, Bernard Gjata, Jean-Yves Hogrel, Oumeya Adjali, Fulvio Mavilio, Thomas Voit, Philippe Moullier, George Dickson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy is a progressive degenerative disease of muscles caused by mutations in the dystrophin gene. Here the authors use AAV vectors to deliver microdystrophin to dogs with muscular dystrophy, and show restoration of dystrophin e
Externí odkaz:
https://doaj.org/article/d425f7f6bf364aa99c6850ae61ecdd6b
Akademický článek
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Autor:
Arnaud Paré, Baptiste Charbonnier, Joëlle Veziers, Caroline Vignes, Maeva Dutilleul, Gonzague De Pinieux, Boris Laure, Adeline Bossard, Annaëlle Saucet-Zerbib, Gwenola Touzot-Jourde, Pierre Weiss, Pierre Corre, Olivier Gauthier, David Marchat
Publikováno v:
Acta biomaterialia. 154
The reconstruction of massive segmental mandibular bone defects (SMDs) remains challenging even today; the current gold standard in human clinics being vascularized bone transplantation (VBT). As alternative to this onerous approach, bone tissue engi
Autor:
Pascal Janvier, Jean-Michel Bouler, Maeva Dutilleul, Elise Verron, Manon Dupleichs, Olivier Gauthier, M. Masson
Publikováno v:
The Journal of Pain
The Journal of Pain, 2018, 00, pp.1-12. ⟨10.1016/j.jpain.2018.04.014⟩
The Journal of Pain, 2018, 00, pp.1-12. ⟨10.1016/j.jpain.2018.04.014⟩
International audience; Abstract: Postoperative pain after bone reconstruction is a serious complication that could jeopardize the global success of a surgery. This pain must be controlled and minimized during the first 3 to 4 postoperative days to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da863f17292591f1345770c04ee4344f
https://www.hal.inserm.fr/inserm-01848181
https://www.hal.inserm.fr/inserm-01848181
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Virginie François, Oumeya Adjali, Jean-Yves Hogrel, George Dickson, Thibaut Larcher, Maeva Dutilleul, Taeyoung Koo, Marie Montus, Stéphane Ederhy, Stéphane Blot, M. Allais, Carole Masurier, Alberto Malerba, Marie Devaux, B. Matot, Karim Wahbi, Sophie Moullec, Bernard Gjata, Bodvael Fraysse, Laurent Servais, Fulvio Mavilio, Inès Barthélémy, Pierre G. Carlier, Takis Athanasopoulos, Isabelle Testault, Samia Martin, Jack-Yves Deschamps, Philippe Moullier, Federico Mingozzi, Philippe Veron, Christophe Georger, Johanne Le Duff, Caroline Le Guiner, Thomas Voit, Jean-Laurent Thibaut
Publikováno v:
Nature Communications
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy (DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin gene. Gene therapy using highly functional microdystrophin genes and recombinant adeno-associated virus (rAAV) vectors is an attra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c348d77df95e4b68a2b7f4ada280b2b
https://univ-evry.hal.science/hal-02179396
https://univ-evry.hal.science/hal-02179396
Autor:
Myriam Le Ferrec, Jean-Michel Bouler, Franck Fayon, Charlotte Mellier, Alain Walcarius, Christelle Despas, Pascal Janvier, Olivier Gauthier, Florian Boukhechba, Bruno Bujoli, Maeva Dutilleul, François-Xavier Lefèvre, Valérie Montouillout
Publikováno v:
Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2017, 62, pp.328-339. ⟨10.1016/j.actbio.2017.08.040⟩
Acta Biomaterialia, 2017, 62, pp.328-339. ⟨10.1016/j.actbio.2017.08.040⟩
Acta Biomaterialia, Elsevier, 2017, 62, pp.328-339. ⟨10.1016/j.actbio.2017.08.040⟩
Acta Biomaterialia, 2017, 62, pp.328-339. ⟨10.1016/j.actbio.2017.08.040⟩
International audience; Two commercial formulations of apatitic calcium phosphate cements (CPCs), Graftys Ò Quickset (QS) and Graftys Ò HBS (HBS), similar in composition but with different initial setting time (7 and 15 min, respectively), were com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746c90c5146832b3c933395ebc829afd
https://www.hal.inserm.fr/inserm-01856304/file/1-s2.0-S1742706117305548-main.pdf
https://www.hal.inserm.fr/inserm-01856304/file/1-s2.0-S1742706117305548-main.pdf
Autor:
Antoine Henry, Pauline Colombier, Maeva Dutilleul, Florent Autrusseau, Jérôme Guicheux, Anne Camus
Publikováno v:
Gordon Research Conference on Cartilage Biology & Pathology
Gordon Research Conference on Cartilage Biology & Pathology, Apr 2017, Lucca, Italy
HAL
Gordon Research Conference on Cartilage Biology & Pathology, Apr 2017, Lucca, Italy
HAL
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a13b5c5f4edd8475672a8507729e01f6
https://hal.archives-ouvertes.fr/hal-01611468
https://hal.archives-ouvertes.fr/hal-01611468
Autor:
Laurent Tesson, Helicia Goubin, Jean-Baptiste Renaud, Thibaut Larcher, Caroline Le Guiner, Yan Cherel, Carine Giovannangeli, Corinne Huchet, Maeva Dutilleul, Ignacio Anegon, Gilles Toumaniantz, Anne De Cian, Lydie Guigand, Jean-Paul Concordet, Séverine Remy, Charlotte Boix, A. Lafoux, Virginie François, Virginie Thepenier
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, Vol 9, Iss 10, p e110371 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
Plos One 10 (9), 13 p.. (2014)
PLoS ONE, Public Library of Science, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, Vol 9, Iss 10, p e110371 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
PLoS ONE, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
Plos One 10 (9), 13 p.. (2014)
International audience; A few animal models of Duchenne muscular dystrophy (DMD) are available, large ones such as pigs or dogs being expensive and difficult to handle. Mdx (X-linked muscular dystrophy) mice only partially mimic the human disease, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c4413cbd0bf7a3aecc2986c1e1475b
https://hal.archives-ouvertes.fr/hal-01190124/document
https://hal.archives-ouvertes.fr/hal-01190124/document
Autor:
Gwladys Gernoux, Marie Devaux, Laurence Dubreil, Nicolas Jaulin, Mickaël Guilbaud, Jack-Yves Deschamps, Thibaut Larcher, Lydie Guigand, Maeva Dutilleul, Caroline Le Guiner, Yan Cherel, Philippe Moullier, Oumeya Adjali
Publikováno v:
16th annual meeting, Salt Lake City, USA, 2013-05-15-2013-05-18
16th annual meeting
16th annual meeting, May 2013, Salt Lake City, United States. 2013
HAL
Molecular Therapy
16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT)
16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States
16th annual meeting
16th annual meeting, May 2013, Salt Lake City, United States. 2013
HAL
Molecular Therapy
16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT)
16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States
After LR delivery of an AAV8 vector expressing GFP in non-human primates, we showed detection of transgene expression until at least 8 months post-injection in contrast to IM where GFP was lost at 3 months post-injection. Interestingly, GFP persisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::82c4f746fa6ab43f7f9119b92ff8865d
http://prodinra.inra.fr/record/191213
http://prodinra.inra.fr/record/191213
Autor:
Yan Cherel, Philippe Veron, F. Barnay-Toutain, Virginie Latournerie, Christian Leborgne, Jean-Laurent Thibaud, Marie Montus, Claire Wary, Nicolas Jaulin, C. Le Guiner, Claire Domenger, Christel Rivière, Oumeya Adjali, H. Goubin, T. Voit, Carole Masurier, Lydie Guigand, N. Delaunay, Philippe Moullier, Sylvie Boutin, Diana Desgue, B. Matot, Gisèle Bonne, Virginie François, J.Y. Hogrel, Maeva Dutilleul, L. Servais, Pierre G. Carlier, Marie Devaux, M. Allais, Sophie Moullec, J. Le Duff, Mickaël Guilbaud, Jack-Yves Deschamps, T. Larche
Publikováno v:
Neuromuscular Disorders. 24:822
We have previously demonstrated that a recombinant adeno-associated virus vector, serotype 8 (rAAV8) carrying a modified U7snRNA sequence promoting exon skipping injected in GRMD by locoregional transvenous perfusion of the forelimb, restores up to 8