Výsledky vyhledávání - "Maedeh Sherafati"

Structure-based drug discovery and antimicrobial activity of ciprofloxacin‐grafted Ugi adducts

Autor: Behnam, Tahmasebi, Aida, Iraji, Maedeh, Sherafati, Ali, Moazzam, Seyed Alireza, Akhlagh, Mehdi, Adib, Mohammad, Mahdavi

Publikováno v: Journal of Biomolecular Structure and Dynamics. :1-10

A new series of ciprofloxacin-derived Ugi adducts were rationally designed and synthesized. The synthesized molecules were explored for their potential antimicrobial activities against four pathogenic microorganisms. Among these derivatives, compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6ed4db45ed008284e5a593cbd9cb58
https://doi.org/10.1080/07391102.2022.2130985

Zobrazit plný text záznamu

Design, synthesis, α‐glucosidase inhibition, pharmacokinetic, and cytotoxic studies of new indole‐carbohydrazide‐phenoxy‐ N ‐phenylacetamide derivatives

Autor: Haleh Hamedifar, Maryam Mohammadi‐Khanaposhtani, Maedeh Sherafati, Milad Noori, Ali Moazam, Samanesadat Hosseini, Bagher Larijani, Mir H. Hajimiri, Mohammad Mahdavi, Mehmet K. Erdogan, Ramazan Gundogdu, Mahinur Kirici, Parham Taslimi, İlhami Gülçin

Publikováno v: Archiv der Pharmazie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::040f7c062cf4e5db86406dfcf4aaa6df
https://doi.org/10.1002/ardp.202200571

Zobrazit plný text záznamu

Design, synthesis and biological evaluation of novel phthalimide-Schiff base-coumarin hybrids as potent α-glucosidase inhibitors

Autor: Mir Hamed Hajimiri, Mohammad Mahdavi, Haleh Hamedifar, Mohammad Ali Faramarzi, Maedeh Sherafati, Shahram Moradi, Nadia Najafabadipour, Mohammad Sadegh Asgari, Mahmood Biglar, Bagher Larijani, Maryam Mohammadi-Khanaposhtani

Publikováno v: Chemical Papers. 74:4379-4388

We have designed and synthesized phthalimide-Schiff base-coumarin hybrids 8a–b, 9a–d, 10a–b, and 11a–d and evaluated them for α-glucosidase inhibitory potential against yeast form of this enzyme. For the synthesis of title compounds 4-hydrox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::039cece2827ea55d9dbdd64bd618eb30
https://doi.org/10.1007/s11696-020-01246-7

Zobrazit plný text záznamu

New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

Autor: Maryam Mohammadi-Khanaposhtani, Hossein Rastegar, İlhami Gülçin, Parham Taslimi, Maedeh Sherafati, Keyvan Pedrood, Ebrahim Barzegari, Bagher Larijani, Roghieh Mirzazadeh, Hojjat Rahmani, Mohammad Sadegh Asgari, Mohammad Mahdavi, Eda M. Üç

Publikováno v: ARCHIV DER PHARMAZIE

A new series of quinoxalin-1,3,4-oxadiazole (10a-l) derivatives was synthesized and evaluated against some metabolic enzymes including human carbonic anhydrase (hCA) isoenzymes I and II (carbonic anhydrases I and II), cholinesterase (acetylcholineste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450b2f71b31186dfe570d183f88ac0b8
https://pubmed.ncbi.nlm.nih.gov/33999440

Zobrazit plný text záznamu

Quinazolinone-dihydropyrano[3,2-b]pyran hybrids as new α-glucosidase inhibitors: Design, synthesis, enzymatic inhibition, docking study and prediction of pharmacokinetic

Autor: Somayeh Mojtabavi, Homa Azizian, Ebrahim Barzegari, Hossein Rastegar, Roghieh Mirzazadeh, Mohammad Sadegh Asgari, Samanesadat Hosseini, Maedeh Sherafati, Mohammad Mahdavi, Ebrahim Zabihi, Mohammad Ali Faramarzi, Bagher Larijani, Maryam Mohammadi-Khanaposhtani, Mir Hamed Hajimiri, Haleh Hamedifar

Publikováno v: Bioorganic chemistry. 109

A series of new quinazolinone-dihydropyrano[3,2-b]pyran derivatives 10A-L were synthesized by simple chemical reactions and were investigated for inhibitory activities against α-glucosidase and α-amylase. New synthesized compounds showed high α-gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5e581649122da5ae6b37792cfca2b1
https://pubmed.ncbi.nlm.nih.gov/33609917

Zobrazit plný text záznamu