Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical Development.

Autor: Maeba T; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.; Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan., Hirata K; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Kotoku M; Akros Pharma Inc., Boston Office, One Broadway, 14th Floor, Cambridge, Massachusetts 02142, United States., Seki N; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Maeda K; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Hirashima S; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Yamanaka H; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Sakai T; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Obika S; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Hori A; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Hara Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Noji S; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Suwa Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Yokota M; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Fujioka S; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Yamaguchi T; Pharmaceutical Division, Japan Tobacco Inc., 3-4-1, Nihonbashi-Honcho, Chuo-ku, Tokyo 103-0023, Japan., Katsuda Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Hata T; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Miyagawa N; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Arita K; Pharmaceutical Division, Japan Tobacco Inc., 3-4-1, Nihonbashi-Honcho, Chuo-ku, Tokyo 103-0023, Japan., Nomura Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Taniguchi T; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Asahina K; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Aratsu Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Naka Y; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Adachi T; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Nomura A; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Akai S; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan., Oshida SI; Central Pharmaceutical Research Institute, Yokohama Research Center, Japan Tobacco Inc., 1-13-2, Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan., Pai S; Akros Pharma Inc., 302 Carnegie Center, Suite 300, Princeton, New Jersey 08540, United States., Crowe P; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Bradley E; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Steensma R; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Tao H; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Fenn M; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Babine R; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Li X; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Thacher S; Orphagen Pharmaceuticals, 11558 Sorrento Valley Road, Suite 4, San Diego, California 92121, United States., Soeta T; Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan., Ukaji Y; Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan., Shiozaki M; Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Jan 25; Vol. 67 (2), pp. 952-970. Date of Electronic Publication: 2024 Jan 03.

SARS-CoV-2 Testing of the Maxillary Sinus Immediately after COVID-19 Recovery.

Autor: Maeba T; Department of Plastic Surgery, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan., Watanabe H; Department of Infectious Disease, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan., Wakuta N; Department of Neurosurgery, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan.

Publikováno v: Plastic and reconstructive surgery. Global open [Plast Reconstr Surg Glob Open] 2023 Apr 26; Vol. 11 (4), pp. e4959. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).

Immunohistochemically Detected Expression of ATRX, TSC2, and PTEN Predicts Clinical Outcomes in Patients With Grade 1 and 2 Pancreatic Neuroendocrine Tumors.

Autor: Uemura J; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Okano K; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Oshima M; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Suto H; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Ando Y; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Kumamoto K; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan., Kadota K; Department of Pathology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Ichihara S; Department of Gastroenterological Surgery, Kagawa Prefectural Central Hospital, Kagawa, Japan., Kokudo Y; Department of Surgery, Kagawa Rosai Hospital, Kagawa, Japan., Maeba T; Department of Surgery, Japan Community Health Care Organization Ritsurin Hospital, Kagawa, Japan., Nanno Y; Division of Hepato-biliary-pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Toyama H; Division of Hepato-biliary-pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Takada Y; Department of Hepato-Biliary-Pancreatic and Brest Surgery, Ehime University Graduate School of Medicine, Ehime, Japan., Shimada M; Department of Digestive and Transplant Surgery, Tokushima University, Tokushima, Japan., Hanazaki K; Department of First Surgery, Kochi University School of Medicine, Kochi, Japan., Masaki T; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Suzuki Y; Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Publikováno v: Annals of surgery [Ann Surg] 2021 Dec 01; Vol. 274 (6), pp. e949-e956.

Long-term follow up of heterotopic liver allograft survival with or without hepatic arterial reconstruction

Autor: Hossain, M.A ^*, Hamamoto, I, Wakabayashi, H, Goda, F, Kobayashi, S, Maeba, T, Maeta, H

Publikováno v: In Transplantation Proceedings 2000 32(7):2254-2257

Lack of collagen α6(IV) chain in mice does not cause severe-to-profound hearing loss or cochlear malformation, a distinct phenotype from nonsyndromic hearing loss with COL4A6 missense mutation.

Autor: Tang S; Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Yonezawa T; Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Maeda Y; Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Ono M; Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Maeba T; Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Miyoshi T; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Momota R; Department of Human Morphology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Tomono Y; Division of Molecular and Cell Biology, Shigei Medical Research Institute, Okayama, Japan., Oohashi T; Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Publikováno v: PloS one [PLoS One] 2021 Apr 13; Vol. 16 (4), pp. e0249909. Date of Electronic Publication: 2021 Apr 13 (Print Publication: 2021).