Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mae M. Lewis"'
Autor:
Melissa R. Soto, Mae M. Lewis, Jasmim Leal, Yuting Pan, Rashmi P. Mohanty, Arian Veyssi, Esther Y. Maier, Brittany J. Heiser, Debadyuti Ghosh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102375- (2024)
For cystic fibrosis patients, a lung-targeted gene therapy would significantly alleviate pulmonary complications associated with morbidity and mortality. However, mucus in the airways and cell entry pose huge delivery barriers for local gene therapy.
Externí odkaz:
https://doaj.org/article/e8f77c73d20b47b7862c329c25cf9246
Autor:
Mae M. Lewis, Melissa R. Soto, Esther Y. Maier, Steven D. Wulfe, Sandy Bakheet, Hannah Obregon, Debadyuti Ghosh
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract Although mRNA lipid nanoparticles (LNPs) are highly effective as vaccines, their efficacy for pulmonary delivery has not yet fully been established. A major barrier to this therapeutic goal is their instability during aerosolization for loca
Externí odkaz:
https://doaj.org/article/09f8130523b74f9c9988e235a0ec8305
Autor:
Madeleine J. Sitton, Charles A. Gersbach, Luke C. Bartelt, Chase L. Beisel, Mae M. Lewis, Kylie A. Gilcrest, Tyler S. Klann, Adrian Pickar-Oliver, Rodolphe Barrangou, Joshua B. Black, Christopher E. Nelson, Alejandro Barrera, Kevin J. Mutchnick, Timothy E. Reddy
Publikováno v:
Nature biotechnology
Class 2 CRISPR-Cas systems, such as Cas9 and Cas12, have been widely used to target DNA sequences in eukaryotic genomes. However, class 1 CRISPR-Cas systems, which represent about 90% of all CRISPR systems in nature, remain largely unexplored for gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12dde971f84f74d0b28d242dc7e1032
https://doi.org/10.1038/s41587-019-0235-7
https://doi.org/10.1038/s41587-019-0235-7
Autor:
Michael Dzuricky, Davoud Mozhdehi, Christian D. Colby, Mae M. Lewis, Fred C. Huang, Kelli M. Luginbuhl, Sinan Xiong, Ashutosh Chilkoti, Stephanie R. Zelenetz, Simone A. Costa
Publikováno v:
Journal of the American Chemical Society. 141(2)
Biological systems use post-translational modifications (PTMs) to control the structure, location, and function of proteins after expression. Despite the ubiquity of PTMs in biology, their use to create genetically encoded recombinant biomaterials is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2823c01368d7862bf339deee8d4d21
https://pubmed.ncbi.nlm.nih.gov/30608674
https://pubmed.ncbi.nlm.nih.gov/30608674
Autor:
White L; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX USA., Lewis M; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX USA., Mastronardi M; Department of Curriculum and Instruction, The University of Texas at Austin, Austin, TX USA., Borrego M; Department of Curriculum and Instruction, The University of Texas at Austin, Austin, TX USA.; Walker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX USA., Rylander HG 3rd; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX USA., Markey MK; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX USA.
Publikováno v:
Biomedical engineering education [Biomed Eng Educ] 2022; Vol. 2 (2), pp. 197-202. Date of Electronic Publication: 2022 Jun 29.