Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Madushan Fernando"'
Autor:
Shivam Vora, Ariel Andrew, Ramyashree Prasanna Kumar, Deborah Nazareth, Alexis Bonfim-Melo, Yoon Lim, Xin Yee Ong, Madushan Fernando, Yaowu He, John D. Hooper, Nigel AJ McMillan, Jelena Urosevic, Jon Travers, Jamal Saeh, Sharad Kumar, Mathew JK Jones, Brian Gabrielli
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-9 (2024)
Abstract Aurora B kinase (AURKB) inhibitors have been trialled in a range of different tumour types but are not approved for any indication. Expression of the human papilloma virus (HPV) oncogenes and loss of retinoblastoma (RB) protein function has
Externí odkaz:
https://doaj.org/article/3d015f58b83e447f8885ff4062e043e7
Autor:
Sile F. Yang, Christopher B. Nelson, Jadon K. Wells, Madushan Fernando, Robert Lu, Joshua A. M. Allen, Lisa Malloy, Noa Lamm, Vincent J. Murphy, Joel P. Mackay, Andrew J. Deans, Anthony J. Cesare, Alexander P. Sobinoff, Hilda A. Pickett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The ATR-CHK1 DNA damage response pathway becomes activated by the exposure of RPA-coated single-stranded DNA (ssDNA) that forms as an intermediate during DNA damage and repair, and as a part of the replication stress response. Here, we ident
Externí odkaz:
https://doaj.org/article/a2cf012d392f4eca877ee8790143a0a5
Autor:
Madushan Fernando, Pascal H. G. Duijf, Martina Proctor, Alexander J. Stevenson, Anna Ehmann, Shivam Vora, Dubravka Skalamera, Mark Adams, Brian Gabrielli
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-11 (2021)
Abstract Defective DNA repair is being demonstrated to be a useful target in cancer treatment. Currently, defective repair is identified by specific gene mutations, however defective repair is a common feature of cancers without these mutations. DNA
Externí odkaz:
https://doaj.org/article/1232e95c12aa4baf83e1909df39172e3
Autor:
Zay Yar Oo, Martina Proctor, Alexander J. Stevenson, Deborah Nazareth, Madushan Fernando, Sheena M. Daignault, Catherine Lanagan, Sebastian Walpole, Vanessa Bonazzi, Dubravka Škalamera, Cameron Snell, Nikolas K. Haass, Jill E. Larsen, Brian Gabrielli
Publikováno v:
Molecular Oncology, Vol 13, Iss 7, Pp 1503-1518 (2019)
Drugs such as gemcitabine that increase replication stress are effective chemotherapeutics in a range of cancer settings. These drugs effectively block replication and promote DNA damage, triggering a cell cycle checkpoint response through the ATR–
Externí odkaz:
https://doaj.org/article/f030e16cdb874773a4afb382b8266e37
Publikováno v:
Cleaner Logistics and Supply Chain, Vol 10, Iss , Pp 100137- (2024)
The Vehicle Routing Problem (VRP) represents a thoroughly investigated domain within operations research, yielding substantial cost savings in global transportation. The fundamental objective of the VRP is to determine the optimal route plan that min
Externí odkaz:
https://doaj.org/article/0013e5b4b7144861b6dbb47aca5bc685
Autor:
Mei Jing Piao, Kyoung Ah Kang, Madushan Fernando, Pincha Devage Sameera, Lakmini Herath, Herath Mudiyanselage Udari, Young Sang Koh, Hee Kyoung Kang, Yung Hyun Choi, Jin Won Hyun
Publikováno v:
International Journal of Medical Sciences; 2024, Vol. 21 Issue 5, p937-948, 12p
Autor:
Herath Mudiyanselage Udari Lakmini Herath, Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Jin Won Hyun
Publikováno v:
International Journal of Medical Sciences; 2024, Vol. 21 Issue 4, p681-689, 9p
Publikováno v:
Journal of Applied Engineering Science. :1-9
Traffic-related analyses are essential to implementing traffic management approaches to create mobility more convenient. In this context, Passenger Car Unit (PCU) values as a uniform measure of vehicles are instrumental in analysis such as traffic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f39b7adff2ce7ae3fdee23a906ce47
https://doi.org/10.5937/jaes0-36600
https://doi.org/10.5937/jaes0-36600
Autor:
Anurag Adhikari, Arunasingam Abayasingam, Chaturaka Rodrigo, David Agapiou, Elvis Pandzic, Nicholas A. Brasher, Bentotage Samitha Madushan Fernando, Elizabeth Keoshkerian, Hui Li, Ha Na Kim, Megan Lord, Gordona Popovic, William Rawlinson, Michael Mina, Jeffrey J. Post, Bernard Hudson, Nicky Gilroy, Dominic Dwyer, Sarah C. Sasson, Branka Grubor-Bauk, Andrew R. Lloyd, Marianne Martinello, Rowena A. Bull, Nicodemus Tedla
Publikováno v:
The Journal of Immunology. 209:1499-1512
Phagocytic responses by effector cells to opsonized viruses have been recognized to play a key role in antiviral immunity. Limited data on coronavirus disease 2019 suggest that the role of Ab-dependent and -independent phagocytosis may contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579649a1d0384f1eebddcf9eeb1f3e31
https://doi.org/10.4049/jimmunol.2200272
https://doi.org/10.4049/jimmunol.2200272
3-Bromo-4,5-dihydroxybenzaldehyde Protects Keratinocytes from Particulate Matter 2.5-Induced Damages
Autor:
Hyun, Ao-Xuan Zhen, Mei-Jing Piao, Kyoung-Ah Kang, Pincha-Devage-Sameera-Madushan Fernando, Herath-Mudiyanselage-Udari-Lakmini Herath, Suk-Ju Cho, Jin-Won
Publikováno v:
Antioxidants; Volume 12; Issue 6; Pages: 1307
Cellular senescence can be activated by several stimuli, including ultraviolet radiation and air pollutants. This study aimed to evaluate the protective effect of marine algae compound 3-bromo-4,5-dihydroxybenzaldehyde (3-BDB) on particulate matter 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9295f4f33161c3e4f7cb68dedfc2c1ac