Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Madusha Goonewardena"'
Autor:
S.J. Linnane, Saly Al-Taei, Malcolm David Mason, Josephine Salimu, Richard Harrop, Madusha Goonewardena, Zsuzsanna Tabi, Jason F. Lester
Publikováno v:
Lung Cancer. 77:312-318
Malignant pleural mesothelioma (MPM) is resistant to conventional treatments. Novel, targeted treatments are hampered by the relative lack of MPM-associated tumour antigens. The aim of this study was to evaluate the level of expression and the releva
Autor:
Stuart Naylor, Joan Hernandez-McClain, Robert J. Amato, Richard Harrop, Jackie de Belin, Madusha Goonewardena, J. P. Willis, Somyata Saxena, J. Jac, William Shingler
Publikováno v:
Journal of Immunotherapy. 32:765-772
Attenuated vaccinia virus, modified vaccinia Ankara (MVA) has been engineered to deliver the tumor antigen 5T4 (TroVax). MVA-5T4 has been evaluated in an open-label phase 2 trial in metastatic renal cell cancer patients in which the vaccine was admin
Autor:
Madusha Goonewardena, Stuart Naylor, Robert J. Amato, Richard Harrop, Robert E. Hawkins, Peter Treasure, Michelle Kelleher, Jackie de Belin, Howard L. Kaufman, William Shingler, M. McDonald
Publikováno v:
Cancer immunology, immunotherapy : CII. 60(6)
Few immunotherapy compounds have demonstrated a direct link between the predicted mode of action of the product and benefit to the patient. Since cancer vaccines are thought to have a delayed therapeutic effect, identification of the active moiety ma
Autor:
Sarah Eastty, Piotr Tomczak, Howard L. Kaufman, William Shingler, M. McDonald, Stuart Naylor, Robert J. Amato, Richard Harrop, Madusha Goonewardena, Cezary Szczylik, Jackie de Belin, Robert E. Hawkins, John A. Thompson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(22)
Purpose: The TroVax Renal Immunotherapy Survival Trial was a randomized, placebo-controlled phase III study that investigated whether modified vaccinia Ankara encoding the tumor antigen 5T4 (MVA-5T4) prolonged survival of patients receiving first-lin
Autor:
Surinder S. Sahota, Alison H. Banham, Christopher D.O. Cooper, Kamal Ait-Tahar, Niklas Zojer, Karen Pulford, C. Madusha Goonewardena, Freda K. Stevenson, Amanda P. Liggins
Publikováno v:
Blood. 108(12)
Immunotherapy is an important treatment option in multiple myeloma (MM), with allotransplantation demonstrating an inducible graft-versus-myeloma effect.[1][1] This could be potentiated by vaccination, first requiring knowledge of tumor-associated an
Autor:
Charles Kelly, Jenny Nobes, Paul Nathan, Ruth E Board, Madusha Goonewardena, Stephen Houston, Steve Nicholson, Neville Davidson, Mark R. Middleton, Sarah Danson, Philippa Corrie, Paul Lorigan, Martin Gore, Andrea Marshall, Jim Barber, Ashita Waterston, Maria Marples, Janet A. Dunn, Ernest Marshall, Mark Harries
Publikováno v:
ResearcherID
LBA9000 Background: Bevacizumab (Bev) is a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF) shown to improve survival in several advanced solid tumors. Multiple adjuvant trials are underway, but trials that have
Autor:
Paul Nathan, Ruth E Board, Neville Davidson, Andrea Marshall, Paul Lorigan, Mark R. Middleton, Charles Kelly, Martin Gore, Janet A. Dunn, Jenny Nobes, Steve Nicholson, Jim Barber, Stephen Houston, Mark Harries, Ernest Marshall, Sarah Danson, Ashita Waterston, Madusha Goonewardena, Philippa Corrie, Maria Marples
Publikováno v:
ResearcherID
LBA9000 The full, final text of this abstract will be available at abstract.asco.org at 7:30 AM (EDT) on Saturday, June, 1, 2013, and in the Annual Meeting Proceedings online supplement to the June 20, 2013, issue of Journal of Clinical Oncology. Ons
Autor:
M. McDonald, Robert J. Amato, Stuart Naylor, J. de Belin, Peter Treasure, Madusha Goonewardena, William Shingler, Howard L. Kaufman, Robert E. Hawkins, Richard Harrop
Publikováno v:
Journal of Clinical Oncology. 29:2542-2542
2542 Background: Few immunotherapy compounds have demonstrated a direct link between the predicted mode of action of the product and benefit to the patient. Since cancer vaccines are thought to hav...
Autor:
Peter Treasure, Richard Harrop, J. de Belin, Madusha Goonewardena, Stuart Naylor, N. Drury, William Shingler
Publikováno v:
European Journal of Cancer Supplements. 6:188
Autor:
Harrop, Richard, Shingler, William, McDonald, Mike, Treasure, Peter, Amato, Robert, Hawkins, Robert, Kaufman, Howard, Belin, Jackie, Kelleher, Michelle, Goonewardena, Madusha, Naylor, Stuart
Publikováno v:
Cancer Immunology, Immunotherapy; Jun2011, Vol. 60 Issue 6, p829-837, 9p