Prevalence, correlates, tolerability-related outcomes, and efficacy-related outcomes of antipsychotic polypharmacy: a systematic review and meta-analysis.

Autor: Højlund M; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark; Clinical Pharmacology, Pharmacy, and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark; Child and Adolescent Mental Health Centre, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark. Electronic address: mhoejlund@health.sdu.dk., Köhler-Forsberg O; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Gregersen AT; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark; Clinical Pharmacology, Pharmacy, and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark., Rohde C; Department of Affective Disorders, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Mellentin AI; Brain Research-Inter-Disciplinary Guided Excellence (BRIDGE), Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Center of Digitalized Psychiatry, Mental Health Services in the Region of Southern Denmark, Odense, Denmark; Department of Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark., Anhøj SJ; Brain Research-Inter-Disciplinary Guided Excellence (BRIDGE), Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Research Unit of Psychiatry, Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Research Unit of Psychiatry, Mental Health Services West, Slagelse, Denmark., Kemp AF; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark; Department of Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark., Fuglsang NB; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Wiuff AC; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Affective Disorders, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Nissen L; Department of Psychiatry Vejle, Mental Health Services in the Region of Southern Denmark, Vejle, Denmark., Sørensen MA; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Madsen NM; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Wagner CB; Early Multimodular Prevention and Intervention Research Institution (EMPIRI), Mental Health Centre, Northern Zealand-Mental Health Services CPH, Copenhagen, Denmark; Mental Health Center Glostrup, Copenhagen University Hospital, Mental Health Services CPH, Copenhagen, Denmark., Agharazi A; Department of Psychiatry Odense, Mental Health Services in the Region of Southern Denmark, Odense, Denmark., Søndergaard C; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark., Sandmark M; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark., Reinhart J; Department of Psychiatry Aabenraa, Mental Health Services in the Region of Southern Denmark, Aabenraa, Denmark., Correll CU; Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA; Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany; German Center for Mental Health (DZPG), partner site Berlin, Germany.

Publikováno v: The lancet. Psychiatry [Lancet Psychiatry] 2024 Dec; Vol. 11 (12), pp. 975-989. Date of Electronic Publication: 2024 Nov 12.

An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders.

Autor: Solmi M; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin Berlin, Berlin, Germany.; Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada.; On Track: The Champlain First Episode Psychosis Program, Department of Mental Health, The Ottawa Hospital, Ottawa, ON, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program University of Ottawa, Ottawa, ON, Canada.; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada., Cortese S; Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.; Solent NHS Trust, Southampton, UK.; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York, NY, USA.; Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.; DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University of Bari 'Aldo Moro', Bari, Italy., Vita G; WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., De Prisco M; Bipolar and Depressive Disorders Unit, Hospìtal Clinic de Barcelona, c. Villarroel, 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Radua J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Imaging of Mood- and Anxiety-Related Disorders (IMARD), CIBERSAM, University of Barcelona, Barcelona, Spain., Dragioti E; University of Ioannina, Research Laboratory Psychology of Patients, Families & Health Professionals, Department of Nursing, School of Health Sciences, Ioannina, Greece.; Linköping University, Pain and Rehabilitation Centre and Department of Health, Medicine and Caring Sciences, Linköping, Sweden., Köhler-Forsberg O; Psychosis Research Unit, Aarhus University Hospital Psychiatry, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Madsen NM; Psychosis Research Unit, Aarhus University Hospital Psychiatry, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Rohde C; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Affective Disorders, Aarhus University Hospital - Psychiatry, Aarhus, Denmark., Eudave L; Faculty of Education and Psychology, University of Navarra, Pamplona, Spain., Aymerich C; Biobizkaia Health Research Institute, Basurto University Hospital, OSI Bilbao-Basurto. University of the Basque Country UPV/EHU. Centro de Investigación en Red de Salud Mental. (CIBERSAM), Instituto de Salud Carlos III. Plaza de Cruces 12, 48903, Barakaldo, Bizkaia, Spain., Pedruzo B; Psychiatry Department, Basurto University Hospital, Bilbao, Spain., Rodriguez V; Department of Psychosis Studies, King's College London, London, UK., Rosson S; Mental Health Department, Local Health Unit ULSS3 Serenissima, Venice, Italy., Sabé M; Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 2, Chemin du Petit-Bel-Air, CH-1226, Thonex, Switzerland., Hojlund M; Department of Psychiatry Aabenraa, Mental Health Services Region of Southern Denmark, Aabenraa, Denmark.; Clinical Pharmacology, Pharmacy, and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Child and Adolescent Mental Health Centre, Mental Health Services Capital Region of Denmark, Copenhagen, Denmark., Catalan A; Biobizkaia Health Research Institute, Basurto University Hospital, OSI Bilbao-Basurto. University of the Basque Country UPV/EHU. Centro de Investigación en Red de Salud Mental. (CIBERSAM), Instituto de Salud Carlos III. Plaza de Cruces 12, 48903, Barakaldo, Bizkaia, Spain., de Luca B; WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., Fornaro M; Department of Psychiatry, Federico II of Naples, Naples, Italy., Ostuzzi G; WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., Barbui C; WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., Salazar-de-Pablo G; Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Child and Adolescent Mental Health Services, South London and Maudsley NHS Foundation Trust, London, UK.; Institute of Psychiatry and Mental Health. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón School of Medicine, Universidad Complutense, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), CIBERSAM, Madrid, Spain., Fusar-Poli P; Department of Psychosis Studies, King's College London, London, UK.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.; Outreach and Support in South London (OASIS) service, NHS South London and Maudsley Foundation Trust, London, UK.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, Munich, Germany., Correll CU; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin Berlin, Berlin, Germany. christoph.correll@charite.de.; The Zucker Hillside Hospital, Northwell Health, New York, NY, USA. christoph.correll@charite.de.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA. christoph.correll@charite.de.; The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Manhasset, NY, USA. christoph.correll@charite.de.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Sep; Vol. 28 (9), pp. 3671-3687. Date of Electronic Publication: 2023 Nov 13.