Effects of a carbohydrate-reduced high-protein diet delivered with meal kits to Danish people with type 2 diabetes: protocol for a 12-month randomised controlled trial

Autor: Sten Madsbad, Faidon Magkos, Jens J Holst, Esben Budtz-Jørgensen, Thure Krarup, Brice Ozenne, Luise H P Kopp, Christina M Søgaard-Hansen, Karen M Zachhau, Rasmus M Bastkjær, Barbara V Andersen, Derek V Byrne, Nora Chaaban, Trine B Klindt, Amirsalar Samkani, Mads J Skytte, Mads N Thomsen

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Introduction The cornerstone in the management of type 2 diabetes (T2D) is lifestyle modification including a healthy diet, typically one in which carbohydrate provides 45%–60% of total energy intake (E%). Nevertheless, systematic reviews and meta-

Externí odkaz: https://doaj.org/article/6c1c8b0897d74876955bc1c5d8c21a1f

Effects of Carbohydrate Restriction on Body Weight and Glycemic Control in Individuals with Type 2 Diabetes:A Randomized Controlled Trial of Efficacy in Real-Life Settings

Autor: Philip Weber, Mads N. Thomsen, Mads Juul Skytte, Amirsalar Samkani, Martin Hansen Carl, Arne Astrup, Jan Frystyk, Jens J. Holst, Bolette Hartmann, Sten Madsbad, Faidon Magkos, Thure Krarup, Steen B. Haugaard

Publikováno v: Weber, P, Thomsen, M N, Skytte, M J, Samkani, A, Carl, M H, Astrup, A, Frystyk, J, Holst, J J, Hartmann, B, Madsbad, S, Magkos, F, Krarup, T & Haugaard, S B 2022, ' Effects of Carbohydrate Restriction on Body Weight and Glycemic Control in Individuals with Type 2 Diabetes : A Randomized Controlled Trial of Efficacy in Real-Life Settings ', Nutrients, vol. 14, no. 24, 5244 . https://doi.org/10.3390/nu14245244
Weber, P, Thomsen, M N, Skytte, M J, Samkani, A, Carl, M H, Astrup, A, Frystyk, J, Holst, J J, Hartmann, B, Madsbad, S, Magkos, F, Krarup, T & Haugaard, S B 2022, ' Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings ', Nutrients, vol. 14, no. 24, 5244 . https://doi.org/10.3390/nu14245244
Nutrients; Volume 14; Issue 24; Pages: 5244

A fully provided, hypocaloric, carbohydrate-reduced high-protein (CRHP) diet compared to a hypocaloric conventional diabetes (CD) diet for 6 weeks improved glycemic control to a greater extent in face of an intended 6% weight loss in individuals with

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Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes:A 6-week randomized controlled trial

Autor: Mads N. Thomsen, Mads J. Skytte, Amirsalar Samkani, Arne Astrup, Mogens Fenger, Jan Frystyk, Bolette Hartmann, Jens J. Holst, Thomas M. Larsen, Sten Madsbad, Faidon Magkos, Jens F. Rehfeld, Steen B. Haugaard, Thure Krarup

Publikováno v: Thomsen, M N, Skytte, M J, Samkani, A, Astrup, A, Fenger, M, Frystyk, J, Hartmann, B, Holst, J J, Larsen, T M, Madsbad, S, Magkos, F, Rehfeld, J F, Haugaard, S B & Krarup, T 2022, ' Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes : A 6-week randomized controlled trial ', Frontiers in nutrition, vol. 9, 933118 . https://doi.org/10.3389/fnut.2022.933118
Thomsen, M N, Skytte, M J, Samkani, A, Astrup, A, Fenger, M, Frystyk, J, Hartmann, B, Holst, J J, Larsen, T M, Madsbad, S, Magkos, F, Rehfeld, J F, Haugaard, S B & Krarup, T 2022, ' Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial ', Frontiers in Nutrition, vol. 9, 933118 . https://doi.org/10.3389/fnut.2022.933118

BackgroundCarbohydrate restriction may benefit β-cell function and glucose metabolism in type 2 diabetes (T2D) but also leads to weight loss which in itself is beneficial.MethodsIn order to determine the additional effect of carbohydrate restriction

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Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes:a randomised controlled trial

Autor: Mads N. Thomsen, Mads J. Skytte, Amirsalar Samkani, Martin H. Carl, Philip Weber, Arne Astrup, Elizaveta Chabanova, Mogens Fenger, Jan Frystyk, Bolette Hartmann, Jens J. Holst, Thomas M. Larsen, Sten Madsbad, Faidon Magkos, Henrik S. Thomsen, Steen B. Haugaard, Thure Krarup

Publikováno v: Thomsen, M N, Skytte, M J, Samkani, A, Carl, M H, Weber, P, Astrup, A, Chabanova, E, Fenger, M, Frystyk, J, Hartmann, B, Holst, J J, Larsen, T M, Madsbad, S, Magkos, F, Thomsen, H S, Haugaard, S B & Krarup, T 2022, ' Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes : a randomised controlled trial ', Diabetologia, vol. 65, no. 3, pp. 506-517 . https://doi.org/10.1007/s00125-021-05628-8
Diabetologia

Aims/hypothesis: Lifestyle modification and weight loss are cornerstones of type 2 diabetes management. However, carbohydrate restriction may have weight-independent beneficial effects on glycaemic control. This has been difficult to demonstrate beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77317e38e35943b9a8e26c805e9ed41
https://portal.findresearcher.sdu.dk/da/publications/0db09eda-adcb-4f0f-a5ac-00df9a1a2bb0

Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

Autor: Amirsalar Samkani, Faidon Magkos, Elizaveta Chabanova, Mads N. Thomsen, Steen B. Haugaard, Arne Astrup, Thomas Larsen, Ahmad Hasan A Alzahrani, Mads J. Skytte, Christian Ritz, Sten Madsbad, Jan Frystyk, Henrik S. Thomsen, Thure Krarup, Jens J. Holst

Publikováno v: Alzahrani, A H A, Skytte, M J, Samkani, A, Thomsen, M N, Astrup, A, Ritz, C, Chabanova, E, Frystyk, J, Holst, J J, Thomsen, H S, Madsbad, S, Haugaard, S B, Krarup, T, Larsen, T M & Magkos, F 2021, ' Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet ', European Journal of Nutrition, vol. 60, no. 8, pp. 4473-4482 . https://doi.org/10.1007/s00394-021-02605-0
Alzahrani, A H, Skytte, M J, Samkani, A, Thomsen, M N, Astrup, A, Ritz, C, Chabanova, E, Frystyk, J, Holst, J J, Thomsen, H S, Madsbad, S, Haugaard, S B, Krarup, T, Larsen, T M & Magkos, F 2021, ' Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet ', European Journal of Nutrition, vol. 60, no. 8, pp. 4473-4482 . https://doi.org/10.1007/s00394-021-02605-0

Purpose: We previously reported beneficial glucoregulatory effects of a fully provided carbohydrate-reduced, high-protein (CRHP) diet in patients with type 2 diabetes mellitus (T2DM) in a crossover 2 × 6-week trial, in which patients maintained thei

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https://portal.findresearcher.sdu.dk/da/publications/edf9b67e-6b04-41a5-a2e2-a974791e6251