Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mads Gabrielsen"'
Autor:
Kok Lian Ho, Mads Gabrielsen, Poay Ling Beh, Chare Li Kueh, Qiu Xian Thong, James Streetley, Wen Siang Tan, David Bhella
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e3000038 (2018)
Macrobrachium rosenbergii nodavirus (MrNV) is a pathogen of freshwater prawns that poses a threat to food security and causes significant economic losses in the aquaculture industries of many developing nations. A detailed understanding of the MrNV v
Externí odkaz:
https://doaj.org/article/a6b0a234275a418db02ace10ea451fd0
Autor:
James P R Connolly, Mads Gabrielsen, Robert J Goldstone, Rhys Grinter, Dai Wang, Richard J Cogdell, Daniel Walker, David G E Smith, Andrew J Roe
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005359 (2016)
The ability of any organism to sense and respond to challenges presented in the environment is critically important for promoting or restricting colonization of specific sites. Recent work has demonstrated that the host metabolite D-serine has the ab
Externí odkaz:
https://doaj.org/article/1dc284a719ef49db90922620316798bb
Autor:
Mads Gabrielsen, Katherine S H Beckham, Victoria A Feher, Caroline E Zetterström, Dai Wang, Sylke Müller, Mikael Elofsson, Rommie E Amaro, Olwyn Byron, Andrew J Roe
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32217 (2012)
Thiol peroxidase, Tpx, has been shown to be a target protein of the salicylidene acylhydrazide class of antivirulence compounds. In this study we present the crystal structures of Tpx from Y. pseudotuberculosis (ypTpx) in the oxidised and reduced sta
Externí odkaz:
https://doaj.org/article/f1d1bcf768034b47ad2805c83446d23a
Autor:
Jayde A Gawthorne, L Evan Reddick, Snezhana N Akpunarlieva, Katherine S H Beckham, John M Christie, Neal M Alto, Mads Gabrielsen, Andrew J Roe
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52962 (2012)
In this work, we describe the utility of Light, Oxygen, or Voltage-sensing (LOV) flavoprotein domains from plant phototropins as a reporter for protein expression and function. Specifically, we used iLOV, an enhanced and more photostable variant of L
Externí odkaz:
https://doaj.org/article/e4119eba0a0a4a3eaec859a4c3afe9bd
Autor:
Michael F. Olson, Joanne Edwards, Emma Shanks, Rachana Patel, Clare Orange, Lynn McGarry, Mads Gabrielsen, Katerina Mardilovich
Supplementary Figure S1: Antibody validation data, disease free progression data, and LIMK1, LIMK2 and metalloproteinase protein expression data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177a1ecceb6d8503fedbd75fc7d63cca
https://doi.org/10.1158/1535-7163.22501720.v1
https://doi.org/10.1158/1535-7163.22501720.v1
Autor:
Michael F. Olson, Joanne Edwards, Emma Shanks, Rachana Patel, Clare Orange, Lynn McGarry, Mads Gabrielsen, Katerina Mardilovich
Supplemental Table S1. Demographic, clinicopathological and outcome data. Supplemental Table S2. LIMK1 association with prostate cancer patient survival. Supplemental Table S3. LIMK2 association with prostate cancer patient survival. Supplemental Tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0be0e55b21900790e54042fa59eb11d
https://doi.org/10.1158/1535-7163.22501717
https://doi.org/10.1158/1535-7163.22501717
Autor:
Michael F. Olson, Joanne Edwards, Emma Shanks, Rachana Patel, Clare Orange, Lynn McGarry, Mads Gabrielsen, Katerina Mardilovich
Prostate cancer affects a large proportion of the male population, and is primarily driven by androgen receptor (AR) activity. First-line treatment typically consists of reducing AR signaling by hormone depletion, but resistance inevitably develops o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::149eac5d49cea0d1a1df03377095c773
https://doi.org/10.1158/1535-7163.c.6536881.v1
https://doi.org/10.1158/1535-7163.c.6536881.v1
Autor:
Michael F. Olson, Joanne Edwards, Emma Shanks, Rachana Patel, Clare Orange, Lynn McGarry, Mads Gabrielsen, Katerina Mardilovich
Legend for Supplementary Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd33fb945aba024350dfb11fb119f96
https://doi.org/10.1158/1535-7163.22501723
https://doi.org/10.1158/1535-7163.22501723
Autor:
Tobias Schmidt, Adrianna Dabrowska, Joseph A Waldron, Kelly Hodge, Grigorios Koulouras, Mads Gabrielsen, June Munro, David C Tack, Gemma Harris, Ewan McGhee, David Scott, Leo M Carlin, Danny Huang, John Le Quesne, Sara Zanivan, Ania Wilczynska, Martin Bushell
Publikováno v:
Nucleic acids research, vol 51, iss 4
Altered eIF4A1 activity promotes translation of highly structured, eIF4A1-dependent oncogene mRNAs at root of oncogenic translational programmes. It remains unclear how these mRNAs recruit and activate eIF4A1 unwinding specifically to facilitate thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd30af1f43661cd10c2521513853ddd
https://escholarship.org/uc/item/6xx8242v
https://escholarship.org/uc/item/6xx8242v
Autor:
Mark A. Nakasone, Karolina A. Majorek, Mads Gabrielsen, Gary J. Sibbet, Brian O. Smith, Danny T. Huang
Publikováno v:
Nature Chemical Biology. 18:422-431
Ubiquitin (Ub) chain types govern distinct biological processes. K48-linked polyUb chains target substrates for proteasomal degradation, but the mechanism of Ub chain synthesis remains elusive due to the transient nature of Ub handover. Here, we pres