Výsledky vyhledávání - "Madoka Terashima"

Akademický článek

KD-409, a Respiratory Syncytial Virus FG Chimeric Protein without the CX3C Chemokine Motif, Is an Efficient Respiratory Syncytial Virus Vaccine Preparation for Passive and Active Immunization in Mice

Autor: Ryo Yamaue, Masaharu Torikai, Madoka Terashima, Hiroaki Mori

Publikováno v: Vaccines, Vol 12, Iss 7, p 753 (2024)

Although respiratory syncytial virus (RSV) vaccine development initiatives have existed for half a century, no candidate has been approved for application at all ages from neonates to children. Developing an effective and safe RSV vaccine for pediatr

Externí odkaz: https://doaj.org/article/26bb458594c6450fa4702b9ec0f545f0

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Akademický článek

Pluripotent stem cell‐based screening identifies CUDC‐907 as an effective compound for restoring the in vitro phenotype of Nakajo‐Nishimura syndrome

Autor: Naoya Kase, Madoka Terashima, Akira Ohta, Akira Niwa, Fumiko Honda‐Ozaki, Yuri Kawasaki, Tatsutoshi Nakahata, Nobuo Kanazawa, Megumu K. Saito

Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 455-464 (2021)

Abstract Nakajo‐Nishimura syndrome (NNS) is an autoinflammatory disorder caused by a homozygous mutations in the PSMB8 gene. The administration of systemic corticosteroids is partially effective, but continuous treatment causes severe side effects.

Externí odkaz: https://doaj.org/article/ab2d0a8881024d599625298f42662775

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Pluripotent stem cell‐based screening identifies CUDC‐907 as an effective compound for restoring the in vitro phenotype of Nakajo‐Nishimura syndrome

Autor: Nobuo Kanazawa, Naoya Kase, Fumiko Honda-Ozaki, Madoka Terashima, Megumu K. Saito, Yuri Kawasaki, Akira Ohta, Tatsutoshi Nakahata, Akira Niwa

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 455-464 (2021)

Nakajo‐Nishimura syndrome (NNS) is an autoinflammatory disorder caused by a homozygous mutations in the PSMB8 gene. The administration of systemic corticosteroids is partially effective, but continuous treatment causes severe side effects. We previ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9843f26617f87d64bce53f6a317cd1
http://europepmc.org/articles/PMC7900583

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High-throughput Screening with Pluripotent Stem Cells Identifies CUDC-907 as an Effective Compound for Restoring the Proinflammatory Phenotype of Nakajo-Nishimura Syndrome

Autor: Yuri Kawasaki, Akira Ohta, Naoya Kase, Tatsutoshi Nakahata, Akira Niwa, Fumiko Honda-Ozaki, Megumu K. Saito, Madoka Terashima, Nabuo Kanazawa

Nakajo-Nishimura syndrome (NNS) is an autoinflammatory disorder caused by a homozygous mutations in PSMB8 gene. The administration of systemic corticosteroids is partially effective, but continuous treatment causes severe side effects. We previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1a73f9e856347ac1143d2ffd031a8ba
https://doi.org/10.1101/2020.06.01.113894

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Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress

Autor: Fumiko Honda-Ozaki, Haruna Ito, Hongmei Lisa Li, Nobuo Kanazawa, Isao Asaka, Ayako Nagahashi, Tatsutoshi Nakahata, Fukumi Furukawa, Akitsu Hotta, Yuri Kawasaki, Megumu K. Saito, Masakatsu Yanagimachi, Norikazu Saiki, Koichi Igura, Madoka Terashima, Akira Niwa

Publikováno v: Stem Cell Reports

Summary Nakajo-Nishimura syndrome (NNS) is an immunoproteasome-associated autoinflammatory disorder caused by a mutation of the PSMB8 gene. Although dysfunction of the immunoproteasome causes various cellular stresses attributed to the overproduction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab881a61442bbaf07dff09dee4f2b512
http://hdl.handle.net/2433/233014

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983 Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress

Autor: Fumiko Honda-Ozaki, Nobuo Kanazawa, Madoka Terashima, Akira Niwa, Tatsutoshi Nakahata, Megumu K. Saito, Masakatsu Yanagimachi, Fukumi Furukawa

Publikováno v: Journal of Investigative Dermatology. 138:S167

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16d9f3a97ac65aebfe395d2c70360e31
https://doi.org/10.1016/j.jid.2018.03.995

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Photoexcited Crystallography of Diplatinum Complex by Multiple-exposure IP Method

Autor: Madoka Terashima, Minoru Mitsumi, Yoshiki Ozawa, Hidehiro Uekusa, Koshiro Toriumi, Nobuhiro Yasuda, Yuji Ohashi

Publikováno v: Chemistry Letters. 32:62-63

Molecular distortion of a photoexcited diplatinum(II) complex in a single crystal has been directly observed by accurate synchrotron radiation diffraction studies. Photoexcited crystallographic analysis has revealed that a small portion of [Pt2(pop)4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a9c52a0472166f17d9d50c94c05c40c
https://doi.org/10.1246/cl.2003.62

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