Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Madoka Taniai"'
Autor:
Mutsuko Taniguchi, Shigeharu Fukuda, Madoka Taniai, Toshio Ariyasu, Daiki Nagatomo, Miho Aga, Tsunetaka Ohta, Harumi Ariyasu
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
We encapsulated tumor necrosis factor-α(TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147ba5a879f9fcd2c36d95c6254896f4
https://doi.org/10.1155/2015/471468
https://doi.org/10.1155/2015/471468
Autor:
Akiko Ohkawa, Kyoko Minowa, Yasuhiro Abe, Shin-ichi Tsunoda, Tetsuya Nomura, Shinsaku Nakagawa, Haruhiko Kamada, Yohei Mukai, Tsunetaka Ohta, Yasuo Yoshioka, Yasuo Tsutsumi, Hiroko Shibata, Madoka Taniai
Publikováno v:
Biomaterials. 30:6638-6647
Blocking the binding of TNF-alpha to TNF receptor subtype-1 (TNFR1) is an important strategy for the treatment of rheumatoid arthritis (RA). We recently succeeded in developing a TNFR1-selective antagonistic TNF mutant, R1antTNF. Here, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a80d1fe84312a5b3f67deb427ff5951
https://doi.org/10.1016/j.biomaterials.2009.08.041
https://doi.org/10.1016/j.biomaterials.2009.08.041
Autor:
Akira Yamamoto, Peter Vandenabeele, Haruhiko Kamada, Yuriko Yamagata, Tomoaki Yoshikawa, Toshiki Sugita, Bharat B. Aggarwal, Tetsuya Nomura, Yasuo Tsutsumi, Tadanori Mayumi, Madoka Taniai, Yasuhiro Abe, Takao Hayakawa, Kyoko Minowa, Teruya Nakamura, Hiroko Shibata, Shinsaku Nakagawa, Hiroyuki Kayamuro, Shin-ichi Tsunoda, Tsunetaka Ohta, Yasuo Yoshioka, Yohei Mukai, Hiromi Nabeshi, Kazuya Nagano, Akiko Ohkawa, Sunao Imai, Takuya Fujita
Publikováno v:
Journal of Biological Chemistry. 283:998-1007
Tumor necrosis factor-alpha (TNF) induces inflammatory response predominantly through the TNF receptor-1 (TNFR1). Thus, blocking the binding of TNF to TNFR1 is an important strategy for the treatment of many inflammatory diseases, such as hepatitis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17c623646bc30f8d4fc6069de88a777
https://doi.org/10.1074/jbc.m707933200
https://doi.org/10.1074/jbc.m707933200
Autor:
Mutsuko Taniguchi, Toshio Ariyasu, Madoka Taniai, Harumi Ariyasu, Yasuo Tsutsumi, Miho Aga, Shigeto Yamamoto, Yohei Mukai, Tsunetaka Ohta, Chie Ushio, Shigeharu Fukuda, Tadao Tanimoto
Publikováno v:
Journal of Interferon & Cytokine Research. 27:517-524
Although there are at least 13 interferon-alpha (IFN-alpha) subtypes in humans, interactions between the subtypes remain unknown. To understand IFN-alpha interactions, we examined the antiproliferative activities and the receptor binding affinities o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98106b195dc2304389393c000c4e1a3b
https://doi.org/10.1089/jir.2007.0155
https://doi.org/10.1089/jir.2007.0155
Autor:
Hiroko Shibata, Yasuo Yoshioka, Haruhiko Kamada, Maki Kawamura, Takao Hayakawa, Yasuhiro Abe, Takayuki Okamoto, Yoko Yamamoto, Yuriko Yamagata, Yasuo Tsutsumi, Satoshi Nagata, Shinji Ikemizu, Tadanori Mayumi, Yohei Mukai, Kyoko Kobayashi, Shinsaku Nakagawa, Madoka Taniai
Publikováno v:
Clinical Cancer Research. 10:8293-8300
Purpose: In this study, the optimization of antitumor therapy with tumor necrosis factor-α (TNF-α) was attempted. Experimental Design: Using the phage display technique, we created a lysine-deficient mutant TNF-α (mTNF-K90R). This mutant had highe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d71d4062869e0f93e0f8ecf69ce22b
https://doi.org/10.1158/1078-0432.ccr-04-0770
https://doi.org/10.1158/1078-0432.ccr-04-0770
Autor:
Toshihide Nishibata, Yuriko Yamagata, Hiroko Shibata, Yoko Yamamoto, Takayuki Okamoto, Shinsaku Nakagawa, Yasuhiro Abe, Satoshi Nagata, Tadanori Mayumi, Madoka Taniai, Yasuo Tsutsumi, Yasuo Yoshioka, Yohei Mukai, Maki Kawamura, Shinji Ikemizu
Publikováno v:
Biochemical and Biophysical Research Communications. 315:808-814
Recently, we created a lysine-deficient mutant tumor necrosis factor-alpha [mTNF-alpha-Lys(-)] with full bioactivity in vitro compared with wild-type TNF-alpha (wTNF-alpha), and site-specific PEGylation of mTNF-alpha-Lys(-) was found to selectively e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59775f1bbdb236aadaac4fd8a16f51a3
https://doi.org/10.1016/j.bbrc.2004.01.125
https://doi.org/10.1016/j.bbrc.2004.01.125
Autor:
Masashi Kurimoto, Hiroshi Yamauchi, Tadao Tanimoto, Yasukazu Ohmoto, Madoka Taniai, Yoshitaka Morita, Masahiro Yamamura, Masanori Kawashima, Hirofumi Makino
Publikováno v:
Arthritis & Rheumatism. 44:275-285
Objective To examine the levels of interleukin-18 (IL-18) bioactivity within the rheumatoid arthritis (RA) joint, and the differential effects of IL-12 and IL-18 on interferon-γ (IFNγ) production by T cell infiltrates. Methods Expression of IL-18 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90652f4c25cef4e15c453ed4fa979520
https://doi.org/10.1002/1529-0131(200102)44:2<275::aid-anr44>3.0.co
https://doi.org/10.1002/1529-0131(200102)44:2<275::aid-anr44>3.0.co
Autor:
Tetsuki Amano, Masashi Kurimoto, Hirofumi Makino, Tsutomu Takeuchi, Hiroshi Yamauchi, Masanori Kawashima, Tadao Tanimoto, Masahiro Yamamura, Shoji Miyawaki, Madoka Taniai
Publikováno v:
Arthritis & Rheumatism. 44:550-560
Objective Interleukin-18 (IL-18) is a proinflammatory cytokine that is involved in immunologically mediated tissue damage, but its bioactivity is regulated in vivo by its soluble decoy receptor, IL-18 binding protein (IL-18BP). This study was underta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe37aea844121a901861fa274029b5c3
https://doi.org/10.1002/1529-0131(200103)44:3<550::aid-anr103>3.0.co
https://doi.org/10.1002/1529-0131(200103)44:3<550::aid-anr103>3.0.co
Autor:
Toshio Kunikata, Hirotada Kojima, Shimpei Ushio, Takanori Okura, Masashi Kurimoto, Mitsukiyo Fujii, Osamu Sanou, Hakuo Ikegami, Susumu Kobayashi, Tadatoshi Murakami, Kakuji Torigoe, Madoka Taniai, Tsunetaka Ohta, Masao Ikeda
Publikováno v:
Journal of Biological Chemistry. 272:25737-25742
Interleukin (IL)-18 was identified as a molecule that induces IFN-γ production and enhances NK cell cytotoxicity. In this paper, we report upon the purification and characterization of human IL-18 receptor (hIL-18R). We selected the Hodgkin’s dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef41e4401927783baf9a252467fe2ad
https://doi.org/10.1074/jbc.272.41.25737
https://doi.org/10.1074/jbc.272.41.25737
Autor:
Kanso Iwaki, Shimpei Ushio, Tsunetaka Ohta, Kazuhisa Sugimura, Masashi Kurimoto, Madoka Taniai, Shigeharu Fukuda
Publikováno v:
Microbiology and Immunology. 39:393-400
We found that mycoplasma-infected cells have a higher ability to metastasize in vivo than non-mycoplasma-infected cells. To investigate this phenomenon, we obtained a monoclonal antibody, MAb 243-5, by immunization with Mycoplasma arginini-infected R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48a2a54da143967a046af30598e2040
https://doi.org/10.1111/j.1348-0421.1995.tb02218.x
https://doi.org/10.1111/j.1348-0421.1995.tb02218.x