Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Madoka Ikemoto‐Uezumi"'
Autor:
Takashi Chaen, Tamaki Kurosawa, Kazuhisa Kishi, Noriyuki Kaji, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Masatoshi Hori
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101478- (2023)
Mesenchymal stromal cells in the muscle layer of the large intestine are essential for the regulation of intestinal motility. They form electrogenic syncytia with the smooth muscle and interstitial cells of Cajal (ICCs) to regulate smooth muscle cont
Externí odkaz:
https://doaj.org/article/6018e1343e3b4eb98474719727043fa8
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101593- (2022)
Summary: We recently demonstrated that mesenchymal progenitors play a critical role in regulating satellite cell-dependent myonuclear accretion during overload-induced muscle hypertrophy. Here, we describe the detailed protocol for whole-mount immuno
Externí odkaz:
https://doaj.org/article/99b4de64e6e64eee8defc10f74f8f609
Autor:
Tamaki Kurosawa, Momo Goto, Noriyuki Kaji, Satoshi Aikiyo, Taiki Mihara, Madoka Ikemoto-Uezumi, Masashi Toyoda, Nobuo Kanazawa, Tatsu Nakazawa, Masatoshi Hori, Akiyoshi Uezumi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Liver cirrhosis is a critical health problem associated with several complications, including skeletal muscle atrophy, which adversely affects the clinical outcome of patients independent of their liver functions. However, the precise mechan
Externí odkaz:
https://doaj.org/article/868eb41be18642779815025de666f20d
Autor:
Akihiro Kaneshige, Takayuki Kaji, Hayato Saito, Tatsuyoshi Higashimoto, Ayasa Nakamura, Tamaki Kurosawa, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, So-ichiro Fukada
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101307- (2022)
Summary: Muscle satellite cells (MuSCs) supply nuclei to existing myofibers in response to mechanical loading. This myonuclear accretion is critical for efficient muscle hypertrophy. Herein, we present protocols for the detection of MuSC-derived new
Externí odkaz:
https://doaj.org/article/d58ac40377aa4dabb61c12f982ab7c79
Autor:
Yuki Yoshimoto, Akiyoshi Uezumi, Madoka Ikemoto-Uezumi, Kaori Tanaka, Xinyi Yu, Tamaki Kurosawa, Shinsei Yambe, Kazumitsu Maehara, Yasuyuki Ohkawa, Yusuke Sotomaru, Chisa Shukunami
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The musculoskeletal system is integrated by tendons that are characterized by the expression of scleraxis (Scx), a functionally important transcription factor. Here, we newly developed a tenocyte induction method using induced pluripotent stem cells
Externí odkaz:
https://doaj.org/article/1d3079a60d864623becd1ac8a7366eaf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Adult skeletal muscle has a remarkable ability to regenerate. Regeneration of mature muscle fibers is dependent on muscle stem cells called satellite cells. Although they are normally in a quiescent state, satellite cells are rapidly activated after
Externí odkaz:
https://doaj.org/article/df36b5fc57ca47b0832c3e08c240693d
Autor:
Lidan Zhang, Yu-taro Noguchi, Hiroyuki Nakayama, Takayuki Kaji, Kazutake Tsujikawa, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Yoshiaki Okada, Takefumi Doi, Shuichi Watanabe, Thomas Braun, Yasushi Fujio, So-ichiro Fukada
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2154-2163.e5 (2019)
Summary: Quiescence is a fundamental property of adult stem cells. Recent evidence indicates that quiescence is not a default state but requires active signaling that prevents accidental or untimely activation of stem cells. The calcitonin receptor (
Externí odkaz:
https://doaj.org/article/99cda14a19464c3f9dc5a5a5a47ba523
Autor:
Akiyoshi Uezumi, Masashi Nakatani, Madoka Ikemoto-Uezumi, Naoki Yamamoto, Mitsuhiro Morita, Asami Yamaguchi, Harumoto Yamada, Takehiro Kasai, Satoru Masuda, Asako Narita, Yuko Miyagoe-Suzuki, Shin’ichi Takeda, So-ichiro Fukada, Ichizo Nishino, Kunihiro Tsuchida
Publikováno v:
Stem Cell Reports, Vol 7, Iss 2, Pp 263-278 (2016)
Skeletal muscle contains two distinct stem/progenitor populations. One is the satellite cell, which acts as a muscle stem cell, and the other is the mesenchymal progenitor, which contributes to muscle pathogeneses such as fat infiltration and fibrosi
Externí odkaz:
https://doaj.org/article/1ed32a83306f4a04a97862709baae44e
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb9f5956e51b00cf6877c2a2d14af0f
https://doi.org/10.1007/978-1-0716-3036-5_9
https://doi.org/10.1007/978-1-0716-3036-5_9
Autor:
Yuki Nagata, Tohru Kiyono, Kikuo Okamura, Yu-Ichi Goto, Masafumi Matsuo, Madoka Ikemoto-Uezumi, Naohiro Hashimoto
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188821 (2017)
Duchenne muscular dystrophy (DMD) is a severe X-linked recessive muscle disorder caused by mutations in the dystrophin gene. Nonetheless, secondary processes involving perturbation of muscle regeneration probably exacerbate disease progression, resul
Externí odkaz:
https://doaj.org/article/5a9b1f09c7f04db2a63cc93a52fac9e0