Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Madison Schank"'
Autor:
Ling Wang, Juan Zhao, Madison Schank, Addison C. Hill, Puja Banik, Yi Zhang, Xiao Y. Wu, Janet W. Lightner, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Despite effective control of HIV replication by antiretroviral therapy (ART), a significant number of people living with HIV (PLWH) fail to achieve complete immune reconstitution and thus are deemed immune non-responders (INRs). Compared with immune
Externí odkaz:
https://doaj.org/article/ddb58edf242448ef8caf4bdb5f38788c
Autor:
Xindi Dang, Dechao Cao, Juan Zhao, Madison Schank, Sushant Khanal, Lam Ngoc Thao Nguyen, Xiao Y. Wu, Yi Zhang, Jinyu Zhang, Yong Jiang, Shunbin Ning, Ling Wang, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
T cells are crucial for controlling viral infections; however, the mechanisms that dampen their responses during viral infections remain incompletely understood. Here, we studied the role and mechanisms of mitochondrial topoisomerase 1 (Top1mt) inhib
Externí odkaz:
https://doaj.org/article/948e813200ce459ca33cd08c161976bc
Autor:
Dechao Cao, Sushant Khanal, Ling Wang, Zhengke Li, Juan Zhao, Lam Nhat Nguyen, Lam Ngoc Thao Nguyen, Xindi Dang, Madison Schank, Bal Krishna Chand Thakuri, Jinyu Zhang, Zeyuan Lu, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f201fe86fcd94344ba8ecb91226cf6e8
Autor:
Ling Wang, Juan Zhao, Lam N. T. Nguyen, James L. Adkins, Madison Schank, Sushant Khanal, Lam N. Nguyen, Xindi Dang, Dechao Cao, Bal Krishna Chand Thakuri, Zeyuan Lu, Jinyu Zhang, Yi Zhang, Xiao Y. Wu, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The recent COVID-19 pandemic poses a serious threat to global public health, thus there is an urgent need to define the molecular mechanisms involved in SARS-CoV-2 spike (S) protein-mediated virus entry that is essential for preventing and/o
Externí odkaz:
https://doaj.org/article/65f0c6e757e64853a3c6e721271fd6cb
Autor:
Madison Schank, Juan Zhao, Ling Wang, Lam Ngoc Thao Nguyen, Yi Zhang, Xiao Y. Wu, Jinyu Zhang, Yong Jiang, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Viruses, Vol 15, Iss 5, p 1061 (2023)
We have previously demonstrated mitochondrial dysfunction in aging CD4 T cells from antiretroviral therapy (ART)-controlled people living with HIV (PLWH). However, the underlying mechanisms by which CD4 T cells develop mitochondrial dysfunction in PL
Externí odkaz:
https://doaj.org/article/99ff10a6770e4f6ba07291c74d1a1e02
Autor:
Bal Krishna Chand Thakuri, Jinyu Zhang, Juan Zhao, Lam N. Nguyen, Lam N. T. Nguyen, Sushant Khanal, Dechao Cao, Xindi Dang, Madison Schank, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Zhengke Li, Yong Jiang, Shunbin Ning, Ling Wang, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myel
Externí odkaz:
https://doaj.org/article/a4a3ec38509049228aa48ba468be63bc
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Effectively treating infectious diseases often requires a multi-step approach to target different components involved in disease pathogenesis. Similarly, the COVID-19 pandemic has become a global health crisis that requires a comprehensive understand
Externí odkaz:
https://doaj.org/article/e8ba637fdc454f9599e680f6142436a3
Autor:
Madison Schank, Juan Zhao, Ling Wang, Lam Ngoc Thao Nguyen, Dechao Cao, Xindi Dang, Sushant Khanal, Jinyu Zhang, Yi Zhang, Xiao Y. Wu, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We have previously shown that chronic Hepatitis C virus (HCV) infection can induce DNA damage and immune dysfunctions with excessive oxidative stress in T cells. Furthermore, evidence suggests that HCV contributes to increased susceptibility to metab
Externí odkaz:
https://doaj.org/article/6c22ac2c11054b8986dc0390a4c80550
Autor:
Yingjie Ji, Xindi Dang, Lam Ngoc Thao Nguyen, Lam Nhat Nguyen, Juan Zhao, Dechao Cao, Sushant Khanal, Madison Schank, Xiao Y. Wu, Zheng D. Morrison, Yue Zou, Mohamed El Gazzar, Shunbin Ning, Ling Wang, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Immunity & Ageing, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood. Here, we used CD4 T cells derived from individual
Externí odkaz:
https://doaj.org/article/92ef9d25a39141c98ca35d7cc14daaac
Autor:
Sushant Khanal, Dechao Cao, Jinyu Zhang, Yi Zhang, Madison Schank, Xindi Dang, Lam Ngoc Thao Nguyen, Xiao Y. Wu, Yong Jiang, Shunbin Ning, Juan Zhao, Ling Wang, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Viruses, Vol 14, Iss 9, p 1902 (2022)
The current antiretroviral therapy (ART) for human immunodeficiency virus (HIV) can halt viral replication but cannot eradicate HIV infection because proviral DNA integrated into the host genome remains genetically silent in reservoir cells and is re
Externí odkaz:
https://doaj.org/article/d65d4e59012044a984f9973fd087a43b